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LearnABIN393482
antibody from antibodies-online
Targeting: RNF20
BRE1, BRE1A, FLJ11189, FLJ20382, hBRE1, KAIA2779
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- ELISA [1]
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- Product number
- ABIN393482 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Ring Finger Protein 20 (RNF20) (AA 177-277) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 177-277
- Isotype
- IgG
- Antibody clone number
- 1C6
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells.
Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair.
Human BRE1 is an E3 ubiquitin ligase for Ebp1 tumor suppressor.
The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression.
Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers.
Kim J, Guermah M, McGinty RK, Lee JS, Tang Z, Milne TA, Shilatifard A, Muir TW, Roeder RG
Cell 2009 May 1;137(3):459-71
Cell 2009 May 1;137(3):459-71
Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair.
Svendsen JM, Smogorzewska A, Sowa ME, O'Connell BC, Gygi SP, Elledge SJ, Harper JW
Cell 2009 Jul 10;138(1):63-77
Cell 2009 Jul 10;138(1):63-77
Human BRE1 is an E3 ubiquitin ligase for Ebp1 tumor suppressor.
Liu Z, Oh SM, Okada M, Liu X, Cheng D, Peng J, Brat DJ, Sun SY, Zhou W, Gu W, Ye K
Molecular biology of the cell 2009 Feb;20(3):757-68
Molecular biology of the cell 2009 Feb;20(3):757-68
The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression.
Shema E, Tirosh I, Aylon Y, Huang J, Ye C, Moskovits N, Raver-Shapira N, Minsky N, Pirngruber J, Tarcic G, Hublarova P, Moyal L, Gana-Weisz M, Shiloh Y, Yarden Y, Johnsen SA, Vojtesek B, Berger SL, Oren M
Genes & development 2008 Oct 1;22(19):2664-76
Genes & development 2008 Oct 1;22(19):2664-76
Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers.
Barber TD, McManus K, Yuen KW, Reis M, Parmigiani G, Shen D, Barrett I, Nouhi Y, Spencer F, Markowitz S, Velculescu VE, Kinzler KW, Vogelstein B, Lengauer C, Hieter P
Proceedings of the National Academy of Sciences of the United States of America 2008 Mar 4;105(9):3443-8
Proceedings of the National Academy of Sciences of the United States of America 2008 Mar 4;105(9):3443-8
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- ELISA
