Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- ABIN954734 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Serotonin Receptor 2B (HTR2B) (C-Term), (AA 415-442) antibody
- Antibody type
- Polyclonal
- Antigen
- KLH conjugated synthetic peptide between 415-442 amino acids from the C-terminal region of Human HTR2B Genename: HTR2B
- Description
- Affinity Chromatography on Protein A
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- C-Term,AA 415-442
- Vial size
- 0.4 mL
- Concentration
- 0.25 mg/mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
The 5-HT(2B) receptor plays a key regulatory role in both neuroendocrine tumor cell proliferation and the modulation of the fibroblast component of the neoplastic microenvironment.
Genetic risk factors for hepatopulmonary syndrome in patients with advanced liver disease.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators
Diabetes care 2010 Oct;33(10):2250-3
Diabetes care 2010 Oct;33(10):2250-3
The 5-HT(2B) receptor plays a key regulatory role in both neuroendocrine tumor cell proliferation and the modulation of the fibroblast component of the neoplastic microenvironment.
Svejda B, Kidd M, Giovinazzo F, Eltawil K, Gustafsson BI, Pfragner R, Modlin IM
Cancer 2010 Jun 15;116(12):2902-12
Cancer 2010 Jun 15;116(12):2902-12
Genetic risk factors for hepatopulmonary syndrome in patients with advanced liver disease.
Roberts KE, Kawut SM, Krowka MJ, Brown RS Jr, Trotter JF, Shah V, Peter I, Tighiouart H, Mitra N, Handorf E, Knowles JA, Zacks S, Fallon MB, Pulmonary Vascular Complications of Liver Disease Study Group
Gastroenterology 2010 Jul;139(1):130-9.e24
Gastroenterology 2010 Jul;139(1):130-9.e24
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of HTR2B Antibody (C-term) Cat.-No AP52127PU-N in Mouse spleen tissue lysates (35ug/lane). This demonstrates the HTR2B antibody detected the HTR2B protein (arrow).
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Formalin fixed, paraffin embedded human thyroid tissue reacted with HTR2B Antibody (C-term) Cat.-No AP52127PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining.