Antibody data
- Antibody Data
- Antigen structure
- References [19]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 18892-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18892-1-AP, RRID:AB_10596795
- Product name
- PTRF antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PTRF antibody (Cat. #18892-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Engineering Extracellular Vesicles Restore the Impaired Cellular Uptake and Attenuate Intervertebral Disc Degeneration.
Salidroside-Mediated Autophagic Targeting of Active Src and Caveolin-1 Suppresses Low-Density Lipoprotein Transcytosis across Endothelial Cells.
Homotrimer cavin1 interacts with caveolin1 to facilitate tumor growth and activate microglia through extracellular vesicles in glioma.
EphB1 interaction with caveolin-1 in endothelial cells modulates caveolae biogenesis.
A role for caveola-forming proteins caveolin-1 and CAVIN1 in the pro-invasive response of glioblastoma to osmotic and hydrostatic pressure.
CAV1-CAVIN1-LC3B-mediated autophagy regulates high glucose-stimulated LDL transcytosis.
Synaptotagmin-11 regulates the functions of caveolae and responds to mechanical stimuli in astrocytes.
Correlation of the invasive potential of glioblastoma and expression of caveola-forming proteins caveolin-1 and CAVIN1.
Cavin-1 regulates caveolae-mediated LDL transcytosis: crosstalk in an AMPK/eNOS/ NF-κB/Sp1 loop.
Inducible Fgf13 ablation enhances caveolae-mediated cardioprotection during cardiac pressure overload.
Reactive oxygen species mediate angiotensin II-induced transcytosis of low-density lipoprotein across endothelial cells.
Deciphering caveolar functions by syndapin III KO-mediated impairment of caveolar invagination.
Acetylation of Cavin-1 Promotes Lipolysis in White Adipose Tissue.
Src-dependent phosphorylation of caveolin-1 Tyr-14 promotes swelling and release of caveolae.
Non-caveolar caveolin-1 expression in prostate cancer cells promotes lymphangiogenesis.
Hypoxia inhibits Cavin-1 and Cavin-2 expression and down-regulates caveolae in adipocytes.
Cavin-1/PTRF alters prostate cancer cell-derived extracellular vesicle content and internalization to attenuate extracellular vesicle-mediated osteoclastogenesis and osteoblast proliferation.
Mitsugumin 53 protects the kidney from severe burn injury in mice.
PTRF/Cavin-1 decreases prostate cancer angiogenesis and lymphangiogenesis.
Liao Z, Liu H, Ma L, Lei J, Tong B, Li G, Ke W, Wang K, Feng X, Hua W, Li S, Yang C
ACS nano 2021 Sep 28;15(9):14709-14724
ACS nano 2021 Sep 28;15(9):14709-14724
Salidroside-Mediated Autophagic Targeting of Active Src and Caveolin-1 Suppresses Low-Density Lipoprotein Transcytosis across Endothelial Cells.
Bai X, Jia X, Lu Y, Zhu L, Zhao Y, Cheng W, Shu M, Jin S
Oxidative medicine and cellular longevity 2020;2020:9595036
Oxidative medicine and cellular longevity 2020;2020:9595036
Homotrimer cavin1 interacts with caveolin1 to facilitate tumor growth and activate microglia through extracellular vesicles in glioma.
Wang L, Yang C, Wang Q, Liu Q, Wang Y, Zhou J, Li Y, Tan Y, Kang C
Theranostics 2020;10(15):6674-6694
Theranostics 2020;10(15):6674-6694
EphB1 interaction with caveolin-1 in endothelial cells modulates caveolae biogenesis.
Tiruppathi C, Regmi SC, Wang DM, Mo GCH, Toth PT, Vogel SM, Stan RV, Henkemeyer M, Minshall RD, Rehman J, Malik AB
Molecular biology of the cell 2020 May 15;31(11):1167-1182
Molecular biology of the cell 2020 May 15;31(11):1167-1182
A role for caveola-forming proteins caveolin-1 and CAVIN1 in the pro-invasive response of glioblastoma to osmotic and hydrostatic pressure.
Pu W, Qiu J, Nassar ZD, Shaw PN, McMahon KA, Ferguson C, Parton RG, Riggins GJ, Harris JM, Parat MO
Journal of cellular and molecular medicine 2020 Mar;24(6):3724-3738
Journal of cellular and molecular medicine 2020 Mar;24(6):3724-3738
CAV1-CAVIN1-LC3B-mediated autophagy regulates high glucose-stimulated LDL transcytosis.
Bai X, Yang X, Jia X, Rong Y, Chen L, Zeng T, Deng X, Li W, Wu G, Wang L, Li Y, Zhang J, Xiong Z, Xiong L, Wang Y, Zhu L, Zhao Y, Jin S
Autophagy 2020 Jun;16(6):1111-1129
Autophagy 2020 Jun;16(6):1111-1129
Synaptotagmin-11 regulates the functions of caveolae and responds to mechanical stimuli in astrocytes.
Yan S, Wang Y, Zhang Y, Wang L, Zhao X, Du C, Gao P, Yan F, Liu F, Gong X, Guan Y, Cui X, Wang X, Xi Zhang C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):2609-2624
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):2609-2624
Correlation of the invasive potential of glioblastoma and expression of caveola-forming proteins caveolin-1 and CAVIN1.
Pu W, Nassar ZD, Khabbazi S, Xie N, McMahon KA, Parton RG, Riggins GJ, Harris JM, Parat MO
Journal of neuro-oncology 2019 Jun;143(2):207-220
Journal of neuro-oncology 2019 Jun;143(2):207-220
Cavin-1 regulates caveolae-mediated LDL transcytosis: crosstalk in an AMPK/eNOS/ NF-κB/Sp1 loop.
Bai XL, Yang XY, Li JY, Ye-Li, Jia X, Xiong ZF, Wang YM, Jin S
Oncotarget 2017 Nov 28;8(61):103985-103995
Oncotarget 2017 Nov 28;8(61):103985-103995
Inducible Fgf13 ablation enhances caveolae-mediated cardioprotection during cardiac pressure overload.
Wei EQ, Sinden DS, Mao L, Zhang H, Wang C, Pitt GS
Proceedings of the National Academy of Sciences of the United States of America 2017 May 16;114(20):E4010-E4019
Proceedings of the National Academy of Sciences of the United States of America 2017 May 16;114(20):E4010-E4019
Reactive oxygen species mediate angiotensin II-induced transcytosis of low-density lipoprotein across endothelial cells.
Bian F, Cui J, Zheng T, Jin S
International journal of molecular medicine 2017 Mar;39(3):629-635
International journal of molecular medicine 2017 Mar;39(3):629-635
Deciphering caveolar functions by syndapin III KO-mediated impairment of caveolar invagination.
Seemann E, Sun M, Krueger S, Tröger J, Hou W, Haag N, Schüler S, Westermann M, Huebner CA, Romeike B, Kessels MM, Qualmann B
eLife 2017 Dec 5;6
eLife 2017 Dec 5;6
Acetylation of Cavin-1 Promotes Lipolysis in White Adipose Tissue.
Zhou SR, Guo L, Wang X, Liu Y, Peng WQ, Liu Y, Wei XB, Dou X, Ding M, Lei QY, Qian SW, Li X, Tang QQ
Molecular and cellular biology 2017 Aug 15;37(16)
Molecular and cellular biology 2017 Aug 15;37(16)
Src-dependent phosphorylation of caveolin-1 Tyr-14 promotes swelling and release of caveolae.
Zimnicka AM, Husain YS, Shajahan AN, Sverdlov M, Chaga O, Chen Z, Toth PT, Klomp J, Karginov AV, Tiruppathi C, Malik AB, Minshall RD
Molecular biology of the cell 2016 Jul 1;27(13):2090-106
Molecular biology of the cell 2016 Jul 1;27(13):2090-106
Non-caveolar caveolin-1 expression in prostate cancer cells promotes lymphangiogenesis.
Nassar ZD, Hill MM, Parton RG, Francois M, Parat MO
Oncoscience 2015;2(7):635-45
Oncoscience 2015;2(7):635-45
Hypoxia inhibits Cavin-1 and Cavin-2 expression and down-regulates caveolae in adipocytes.
Regazzetti C, Dumas K, Lacas-Gervais S, Pastor F, Peraldi P, Bonnafous S, Dugail I, Le Lay S, Valet P, Le Marchand-Brustel Y, Tran A, Gual P, Tanti JF, Cormont M, Giorgetti-Peraldi S
Endocrinology 2015 Mar;156(3):789-801
Endocrinology 2015 Mar;156(3):789-801
Cavin-1/PTRF alters prostate cancer cell-derived extracellular vesicle content and internalization to attenuate extracellular vesicle-mediated osteoclastogenesis and osteoblast proliferation.
Inder KL, Ruelcke JE, Petelin L, Moon H, Choi E, Rae J, Blumenthal A, Hutmacher D, Saunders NA, Stow JL, Parton RG, Hill MM
Journal of extracellular vesicles 2014;3
Journal of extracellular vesicles 2014;3
Mitsugumin 53 protects the kidney from severe burn injury in mice.
Wu Y, Huang J, Liu D, Tan J, Peng Y, Yang J, Cui Y, He W, Luo G, Wu J
Burns & trauma 2013;1(3):128-33
Burns & trauma 2013;1(3):128-33
PTRF/Cavin-1 decreases prostate cancer angiogenesis and lymphangiogenesis.
Nassar ZD, Moon H, Duong T, Neo L, Hill MM, Francois M, Parton RG, Parat MO
Oncotarget 2013 Oct;4(10):1844-55
Oncotarget 2013 Oct;4(10):1844-55
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A549 cells were subjected to SDS PAGE followed by western blot with 18892-1-AP(PTRF antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using PTRF antibody 18892-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-PTRF (IP:18892-1-AP, 3ug; Detection:18892-1-AP 1:800) with mouse lung tissue lysate 5160ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas using 18892-1-AP(PTRF antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue