DPABH-09961

antibody from Creative Diagnostics

Targeting: RTN3 ASYIP, HAP, NSPL2, NSPLII, RTN3-A1

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

DPABH-09961

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-09961, RRID:AB_2523338

Product name

Rabbit Anti-Human RTN3 Polyclonal antibody

Antibody type

Polyclonal

Description

This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

50 uL