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- References [9]
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- Western blot [3]
- Immunoprecipitation [1]
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- Product number
- 16258-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16258-1-AP, RRID:AB_2179918
- Product name
- RGS14 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RGS14 antibody (Cat. #16258-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Immunohistochemical field parcellation of the human hippocampus along its antero-posterior axis.
Hepatic regulator of G protein signaling 14 ameliorates NAFLD through activating cAMP-AMPK signaling by targeting Giα1/3.
Defining hippocampal area CA2 in the fox (Vulpes vulpes) brain.
RGS14 regulates PTH- and FGF23-sensitive NPT2A-mediated renal phosphate uptake via binding to the NHERF1 scaffolding protein.
Human genetic variants disrupt RGS14 nuclear shuttling and regulation of LTP in hippocampal neurons.
Modelling cognitive deficits in Parkinson's disease: Is CA2 a gateway for hippocampal synucleinopathy?
14-3-3γ binds regulator of G protein signaling 14 (RGS14) at distinct sites to inhibit the RGS14:Gα(i)-AlF(4)(-) signaling complex and RGS14 nuclear localization.
Regulator of G protein signaling 14 (RGS14) is expressed pre- and postsynaptically in neurons of hippocampus, basal ganglia, and amygdala of monkey and human brain.
Endogenous RGS14 is a cytoplasmic-nuclear shuttling protein that localizes to juxtanuclear membranes and chromatin-rich regions of the nucleus.
González-Arnay E, Pérez-Santos I, Jiménez-Sánchez L, Cid E, Gal B, de la Prida LM, Cavada C
Brain structure & function 2024 Mar;229(2):359-385
Brain structure & function 2024 Mar;229(2):359-385
Hepatic regulator of G protein signaling 14 ameliorates NAFLD through activating cAMP-AMPK signaling by targeting Giα1/3.
Wang J, Guo Y, He Y, Qin Y, Li X, Yang L, Liu K, Xiao L
Molecular metabolism 2024 Feb;80:101882
Molecular metabolism 2024 Feb;80:101882
Defining hippocampal area CA2 in the fox (Vulpes vulpes) brain.
Dudek SM, Phoenix AN, Scappini E, Shepeleva DV, Herbeck YE, Trut LN, Farris S, Kukekova AV
Hippocampus 2023 Jun;33(6):700-711
Hippocampus 2023 Jun;33(6):700-711
RGS14 regulates PTH- and FGF23-sensitive NPT2A-mediated renal phosphate uptake via binding to the NHERF1 scaffolding protein.
Friedman PA, Sneddon WB, Mamonova T, Montanez-Miranda C, Ramineni S, Harbin NH, Squires KE, Gefter JV, Magyar CE, Emlet DR, Hepler JR
The Journal of biological chemistry 2022 May;298(5):101836
The Journal of biological chemistry 2022 May;298(5):101836
Human genetic variants disrupt RGS14 nuclear shuttling and regulation of LTP in hippocampal neurons.
Squires KE, Gerber KJ, Tillman MC, Lustberg DJ, Montañez-Miranda C, Zhao M, Ramineni S, Scharer CD, Saha RN, Shu FJ, Schroeder JP, Ortlund EA, Weinshenker D, Dudek SM, Hepler JR
The Journal of biological chemistry 2021 Jan-Jun;296:100024
The Journal of biological chemistry 2021 Jan-Jun;296:100024
Modelling cognitive deficits in Parkinson's disease: Is CA2 a gateway for hippocampal synucleinopathy?
Cinar E, Yalcin-Cakmakli G, Saka E, Ulusoy A, Yuruker S, Elibol B, Tel BC
Experimental neurology 2020 Aug;330:113357
Experimental neurology 2020 Aug;330:113357
14-3-3γ binds regulator of G protein signaling 14 (RGS14) at distinct sites to inhibit the RGS14:Gα(i)-AlF(4)(-) signaling complex and RGS14 nuclear localization.
Gerber KJ, Squires KE, Hepler JR
The Journal of biological chemistry 2018 Sep 21;293(38):14616-14631
The Journal of biological chemistry 2018 Sep 21;293(38):14616-14631
Regulator of G protein signaling 14 (RGS14) is expressed pre- and postsynaptically in neurons of hippocampus, basal ganglia, and amygdala of monkey and human brain.
Squires KE, Gerber KJ, Pare JF, Branch MR, Smith Y, Hepler JR
Brain structure & function 2018 Jan;223(1):233-253
Brain structure & function 2018 Jan;223(1):233-253
Endogenous RGS14 is a cytoplasmic-nuclear shuttling protein that localizes to juxtanuclear membranes and chromatin-rich regions of the nucleus.
Branch MR, Hepler JR
PloS one 2017;12(9):e0184497
PloS one 2017;12(9):e0184497
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 16258-1-AP(RGS14 antibody) at dilution of 1:1500
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse spleen tissue were subjected to SDS PAGE followed by western blot with 16258-1-AP(RGS14 antibody) at dilution of 1:500
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse testis tissue were subjected to SDS PAGE followed by western blot with 16258-1-AP(RGS14 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RGS14 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RGS14. This antibody recognizes human,mouse,rat antigen. The RGS14 antibody has been validated for the following applications: ELISA, WB, IP analysis.
