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- Antibody Data
- Antigen structure
- References [53]
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- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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- Product number
- 12110-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12110-1-AP, RRID:AB_2159475
- Product name
- PADI2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PADI2 antibody (Cat. #12110-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references GnRH Induces Citrullination of the Cytoskeleton in Murine Gonadotrope Cells.
Co-expression of PADI isoforms during progenitor differentiation enables functional diversity.
Inhibition of protein arginine deiminase II suppresses retinoblastoma in orthotopic transplantation in mice.
Citrullinated fibrinogen-SAAs complex causes vascular metastagenesis.
Proteomic investigation of neural stem cell to oligodendrocyte precursor cell differentiation reveals phosphorylation-dependent Dclk1 processing.
Peptidylarginine Deiminase Type 2 Predicts Tumor Progression and Poor Prognosis in Patients with Curatively Resected Biliary Tract Cancer.
Targeting STING oligomerization with small-molecule inhibitors.
Identification of super-enhancer-driven peptidyl arginine deiminases as potential biomarkers and therapeutic targets for osimertinib-resistant non-small cell lung cancer.
Delayed puberty, gonadotropin abnormalities and subfertility in male Padi2/Padi4 double knockout mice.
Conservation and divergence of myelin proteome and oligodendrocyte transcriptome profiles between humans and mice.
IL-22 Downregulates Peptidylarginine Deiminase-1 in Human Keratinocytes: Adding Another Piece to the IL-22 Puzzle in Epidermal Barrier Formation.
PAD-2-mediated citrullination of nucleophosmin provides an effective target for tumor immunotherapy.
Peptidylarginine deiminase enzymes and citrullinated proteins in female reproductive physiology and associated diseases†.
Progesterone stimulates histone citrullination to increase IGFBP1 expression in uterine cells.
Angiogenic responses in a 3D micro-engineered environment of primary endothelial cells and pericytes.
Citrullination Alters the Antiviral and Immunomodulatory Activities of the Human Cathelicidin LL-37 During Rhinovirus Infection.
Effect of Porphyromonas gingivalis infection on gut dysbiosis and resultant arthritis exacerbation in mouse model.
Peptidylarginine deiminase 2 has potential as both a biomarker and therapeutic target of sepsis.
Neutrophil extracellular traps mediate articular cartilage damage and enhance cartilage component immunogenicity in rheumatoid arthritis.
A Novel Citrullinated Modification of Histone 3 and Its Regulatory Mechanisms Related to IPO-38 Antibody-Labeled Protein.
Peptidylarginine deiminase 4 overexpression resensitizes MCF-7/ADR breast cancer cells to adriamycin via GSK3β/p53 activation.
Neutrophil extracellular traps, B cells, and type I interferons contribute to immune dysregulation in hidradenitis suppurativa.
Inhibiting PAD2 enhances the anti-tumor effect of docetaxel in tamoxifen-resistant breast cancer cells.
Arginine Citrullination at the C-Terminal Domain Controls RNA Polymerase II Transcription.
PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination.
Accumulation of citrullinated glial fibrillary acidic protein in a mouse model of bile duct ligation-induced hepatic fibrosis.
Histone Citrullination Represses MicroRNA Expression, Resulting in Increased Oncogene mRNAs in Somatolactotrope Cells.
The Development of Benzimidazole-Based Clickable Probes for the Efficient Labeling of Cellular Protein Arginine Deiminases (PADs).
Modifying Enzymes Are Elicited by ER Stress, Generating Epitopes That Are Selectively Recognized by CD4(+) T Cells in Patients With Type 1 Diabetes.
Peptidylarginine deiminases 2 and 4 modulate innate and adaptive immune responses in TLR-7-dependent lupus.
BB-Cl-Amidine as a novel therapeutic for canine and feline mammary cancer via activation of the endoplasmic reticulum stress pathway.
The lncRNA HOXA11-AS functions as a competing endogenous RNA to regulate PADI2 expression by sponging miR-125a-5p in liver metastasis of colorectal cancer.
PADI2-Mediated Citrullination Promotes Prostate Cancer Progression.
Role of peptidylarginine deiminase 2 (PAD2) in mammary carcinoma cell migration.
Citrullination regulates the expression of insulin-like growth factor-binding protein 1 (IGFBP1) in ovine uterine luminal epithelial cells.
Protein-arginine deiminase 2 suppresses proliferation of colon cancer cells through protein citrullination.
Downregulation of the Deiminase PADI2 Is an Early Event in Colorectal Carcinogenesis and Indicates Poor Prognosis.
A cellular model reflecting the phenotypic heterogeneity of mutant HRAS driven squamous cell carcinoma.
GnRH Stimulates Peptidylarginine Deiminase Catalyzed Histone Citrullination in Gonadotrope Cells.
Decreased severity of experimental autoimmune arthritis in peptidylarginine deiminase type 4 knockout mice.
Significant impact of miRNA-target gene networks on genetics of human complex traits.
Peptidylarginine deiminase 1-catalyzed histone citrullination is essential for early embryo development.
Chemical Proteomic Platform To Identify Citrullinated Proteins.
Targeted H3R26 deimination specifically facilitates estrogen receptor binding by modifying nucleosome structure.
PAD2 overexpression in transgenic mice promotes spontaneous skin neoplasia.
Identification of macrophage extracellular trap-like structures in mammary gland adipose tissue: a preliminary study.
Potential role for PAD2 in gene regulation in breast cancer cells.
Identification of PADI2 as a potential breast cancer biomarker and therapeutic target.
ATP induces protein arginine deiminase 2-dependent citrullination in mast cells through the P2X7 purinergic receptor.
Comparative analysis of peptidylarginine deiminase-2 expression in canine, feline and human mammary tumours.
Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor α target gene activation.
Genome-wide analysis reveals PADI4 cooperates with Elk-1 to activate c-Fos expression in breast cancer cells.
Potential role for peptidylarginine deiminase 2 (PAD2) in citrullination of canine mammary epithelial cell histones.
Quigley EB, DeVore SB, Khan SA, Geisterfer ZM, Rothfuss HM, Sequoia AO, Thompson PR, Gatlin JC, Cherrington BD, Navratil AM
International journal of molecular sciences 2024 Mar 10;25(6)
International journal of molecular sciences 2024 Mar 10;25(6)
Co-expression of PADI isoforms during progenitor differentiation enables functional diversity.
Vikhe Patil K, Meijer M, Mak KH, Yang W, Falcão AM, Castelo-Branco G, Genander M
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2023 Nov 20;378(1890):20220451
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2023 Nov 20;378(1890):20220451
Inhibition of protein arginine deiminase II suppresses retinoblastoma in orthotopic transplantation in mice.
Kim S, Song YK, Cho CS, Kim HJ, Fang S, Jo DH, Kim H
Oncology reports 2023 Jul;50(1)
Oncology reports 2023 Jul;50(1)
Citrullinated fibrinogen-SAAs complex causes vascular metastagenesis.
Han Y, Tomita T, Kato M, Ashihara N, Higuchi Y, Matoba H, Wang W, Hayashi H, Itoh Y, Takahashi S, Kurita H, Nakayama J, Okumura N, Hiratsuka S
Nature communications 2023 Aug 24;14(1):4960
Nature communications 2023 Aug 24;14(1):4960
Proteomic investigation of neural stem cell to oligodendrocyte precursor cell differentiation reveals phosphorylation-dependent Dclk1 processing.
Hardt R, Dehghani A, Schoor C, Gödderz M, Cengiz Winter N, Ahmadi S, Sharma R, Schork K, Eisenacher M, Gieselmann V, Winter D
Cellular and molecular life sciences : CMLS 2023 Aug 18;80(9):260
Cellular and molecular life sciences : CMLS 2023 Aug 18;80(9):260
Peptidylarginine Deiminase Type 2 Predicts Tumor Progression and Poor Prognosis in Patients with Curatively Resected Biliary Tract Cancer.
Lin HY, Yu CC, Chi CL, Wei CK, Yin WY, Tseng CE, Li SC
Cancers 2023 Aug 16;15(16)
Cancers 2023 Aug 16;15(16)
Targeting STING oligomerization with small-molecule inhibitors.
Humphries F, Shmuel-Galia L, Jiang Z, Zhou JY, Barasa L, Mondal S, Wilson R, Sultana N, Shaffer SA, Ng SL, Pesiridis GS, Thompson PR, Fitzgerald KA
Proceedings of the National Academy of Sciences of the United States of America 2023 Aug 15;120(33):e2305420120
Proceedings of the National Academy of Sciences of the United States of America 2023 Aug 15;120(33):e2305420120
Identification of super-enhancer-driven peptidyl arginine deiminases as potential biomarkers and therapeutic targets for osimertinib-resistant non-small cell lung cancer.
Li H, Muhetaer G, Xie Y, Yao K, Ma Q, Guan H, Xing S, Huang X, Zhou J
Frontiers in pharmacology 2022;13:1071365
Frontiers in pharmacology 2022;13:1071365
Delayed puberty, gonadotropin abnormalities and subfertility in male Padi2/Padi4 double knockout mice.
Sams KL, Mukai C, Marks BA, Mittal C, Demeter EA, Nelissen S, Grenier JK, Tate AE, Ahmed F, Coonrod SA
Reproductive biology and endocrinology : RB&E 2022 Oct 12;20(1):150
Reproductive biology and endocrinology : RB&E 2022 Oct 12;20(1):150
Conservation and divergence of myelin proteome and oligodendrocyte transcriptome profiles between humans and mice.
Gargareta VI, Reuschenbach J, Siems SB, Sun T, Piepkorn L, Mangana C, Späte E, Goebbels S, Huitinga I, Möbius W, Nave KA, Jahn O, Werner HB
eLife 2022 May 11;11
eLife 2022 May 11;11
IL-22 Downregulates Peptidylarginine Deiminase-1 in Human Keratinocytes: Adding Another Piece to the IL-22 Puzzle in Epidermal Barrier Formation.
Padhi A, Srivastava A, Ramesh A, Ehrström M, Simon M, Sonkoly E, Eidsmo L, Bergman P, Lysell J
The Journal of investigative dermatology 2022 Feb;142(2):333-342.e6
The Journal of investigative dermatology 2022 Feb;142(2):333-342.e6
PAD-2-mediated citrullination of nucleophosmin provides an effective target for tumor immunotherapy.
Choudhury RH, Symonds P, Paston SJ, Daniels I, Cook KW, Gijon M, Metheringham RL, Brentville VA, Durrant LG
Journal for immunotherapy of cancer 2022 Feb;10(2)
Journal for immunotherapy of cancer 2022 Feb;10(2)
Peptidylarginine deiminase enzymes and citrullinated proteins in female reproductive physiology and associated diseases†.
Christensen AO, Li G, Young CH, Snow B, Khan SA, DeVore SB, Edwards S, Bouma GJ, Navratil AM, Cherrington BD, Rothfuss HM
Biology of reproduction 2022 Dec 10;107(6):1395-1410
Biology of reproduction 2022 Dec 10;107(6):1395-1410
Progesterone stimulates histone citrullination to increase IGFBP1 expression in uterine cells.
Young CH, Snow B, DeVore SB, Mohandass A, Nemmara VV, Thompson PR, Thyagarajan B, Navratil AM, Cherrington BD
Reproduction (Cambridge, England) 2021 Jul 8;162(2):117-127
Reproduction (Cambridge, England) 2021 Jul 8;162(2):117-127
Angiogenic responses in a 3D micro-engineered environment of primary endothelial cells and pericytes.
Bai J, Khajavi M, Sui L, Fu H, Tarakkad Krishnaji S, Birsner AE, Bazinet L, Kamm RD, D'Amato RJ
Angiogenesis 2021 Feb;24(1):111-127
Angiogenesis 2021 Feb;24(1):111-127
Citrullination Alters the Antiviral and Immunomodulatory Activities of the Human Cathelicidin LL-37 During Rhinovirus Infection.
Casanova V, Sousa FH, Shakamuri P, Svoboda P, Buch C, D'Acremont M, Christophorou MA, Pohl J, Stevens C, Barlow PG
Frontiers in immunology 2020;11:85
Frontiers in immunology 2020;11:85
Effect of Porphyromonas gingivalis infection on gut dysbiosis and resultant arthritis exacerbation in mouse model.
Hamamoto Y, Ouhara K, Munenaga S, Shoji M, Ozawa T, Hisatsune J, Kado I, Kajiya M, Matsuda S, Kawai T, Mizuno N, Fujita T, Hirata S, Tanimoto K, Nakayama K, Kishi H, Sugiyama E, Kurihara H
Arthritis research & therapy 2020 Oct 19;22(1):249
Arthritis research & therapy 2020 Oct 19;22(1):249
Peptidylarginine deiminase 2 has potential as both a biomarker and therapeutic target of sepsis.
Tian Y, Qu S, Alam HB, Williams AM, Wu Z, Deng Q, Pan B, Zhou J, Liu B, Duan X, Ma J, Mondal S, Thompson PR, Stringer KA, Standiford TJ, Li Y
JCI insight 2020 Oct 15;5(20)
JCI insight 2020 Oct 15;5(20)
Neutrophil extracellular traps mediate articular cartilage damage and enhance cartilage component immunogenicity in rheumatoid arthritis.
Carmona-Rivera C, Carlucci PM, Goel RR, James E, Brooks SR, Rims C, Hoffmann V, Fox DA, Buckner JH, Kaplan MJ
JCI insight 2020 Jul 9;5(13)
JCI insight 2020 Jul 9;5(13)
A Novel Citrullinated Modification of Histone 3 and Its Regulatory Mechanisms Related to IPO-38 Antibody-Labeled Protein.
Song S, Xiang Z, Li J, Ji J, Yan R, Zhu Z, Yu Y
Frontiers in oncology 2019;9:304
Frontiers in oncology 2019;9:304
Peptidylarginine deiminase 4 overexpression resensitizes MCF-7/ADR breast cancer cells to adriamycin via GSK3β/p53 activation.
Zhou Q, Song C, Liu X, Qin H, Miao L, Zhang X
Cancer management and research 2019;11:625-636
Cancer management and research 2019;11:625-636
Neutrophil extracellular traps, B cells, and type I interferons contribute to immune dysregulation in hidradenitis suppurativa.
Byrd AS, Carmona-Rivera C, O'Neil LJ, Carlucci PM, Cisar C, Rosenberg AZ, Kerns ML, Caffrey JA, Milner SM, Sacks JM, Aliu O, Broderick KP, Reichner JS, Miller LS, Kang S, Robinson WH, Okoye GA, Kaplan MJ
Science translational medicine 2019 Sep 4;11(508)
Science translational medicine 2019 Sep 4;11(508)
Inhibiting PAD2 enhances the anti-tumor effect of docetaxel in tamoxifen-resistant breast cancer cells.
Li F, Miao L, Xue T, Qin H, Mondal S, Thompson PR, Coonrod SA, Liu X, Zhang X
Journal of experimental & clinical cancer research : CR 2019 Oct 10;38(1):414
Journal of experimental & clinical cancer research : CR 2019 Oct 10;38(1):414
Arginine Citrullination at the C-Terminal Domain Controls RNA Polymerase II Transcription.
Sharma P, Lioutas A, Fernandez-Fuentes N, Quilez J, Carbonell-Caballero J, Wright RHG, Di Vona C, Le Dily F, Schüller R, Eick D, Oliva B, Beato M
Molecular cell 2019 Jan 3;73(1):84-96.e7
Molecular cell 2019 Jan 3;73(1):84-96.e7
PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination.
Falcão AM, Meijer M, Scaglione A, Rinwa P, Agirre E, Liang J, Larsen SC, Heskol A, Frawley R, Klingener M, Varas-Godoy M, Raposo AASF, Ernfors P, Castro DS, Nielsen ML, Casaccia P, Castelo-Branco G
Cell reports 2019 Apr 23;27(4):1090-1102.e10
Cell reports 2019 Apr 23;27(4):1090-1102.e10
Accumulation of citrullinated glial fibrillary acidic protein in a mouse model of bile duct ligation-induced hepatic fibrosis.
Kim SE, Park JW, Kim MJ, Jang B, Jeon YC, Kim HJ, Ishigami A, Kim HS, Suk KT, Kim DJ, Park CK, Choi EK, Jang MK
PloS one 2018;13(8):e0201744
PloS one 2018;13(8):e0201744
Histone Citrullination Represses MicroRNA Expression, Resulting in Increased Oncogene mRNAs in Somatolactotrope Cells.
DeVore SB, Young CH, Li G, Sundararajan A, Ramaraj T, Mudge J, Schilkey F, Muth A, Thompson PR, Cherrington BD
Molecular and cellular biology 2018 Oct 1;38(19)
Molecular and cellular biology 2018 Oct 1;38(19)
The Development of Benzimidazole-Based Clickable Probes for the Efficient Labeling of Cellular Protein Arginine Deiminases (PADs).
Nemmara VV, Subramanian V, Muth A, Mondal S, Salinger AJ, Maurais AJ, Tilvawala R, Weerapana E, Thompson PR
ACS chemical biology 2018 Mar 16;13(3):712-722
ACS chemical biology 2018 Mar 16;13(3):712-722
Modifying Enzymes Are Elicited by ER Stress, Generating Epitopes That Are Selectively Recognized by CD4(+) T Cells in Patients With Type 1 Diabetes.
Marre ML, McGinty JW, Chow IT, DeNicola ME, Beck NW, Kent SC, Powers AC, Bottino R, Harlan DM, Greenbaum CJ, Kwok WW, Piganelli JD, James EA
Diabetes 2018 Jul;67(7):1356-1368
Diabetes 2018 Jul;67(7):1356-1368
Peptidylarginine deiminases 2 and 4 modulate innate and adaptive immune responses in TLR-7-dependent lupus.
Liu Y, Lightfoot YL, Seto N, Carmona-Rivera C, Moore E, Goel R, O'Neil L, Mistry P, Hoffmann V, Mondal S, Premnath PN, Gribbons K, Dell'Orso S, Jiang K, Thompson PR, Sun HW, Coonrod SA, Kaplan MJ
JCI insight 2018 Dec 6;3(23)
JCI insight 2018 Dec 6;3(23)
BB-Cl-Amidine as a novel therapeutic for canine and feline mammary cancer via activation of the endoplasmic reticulum stress pathway.
Ledet MM, Anderson R, Harman R, Muth A, Thompson PR, Coonrod SA, Van de Walle GR
BMC cancer 2018 Apr 12;18(1):412
BMC cancer 2018 Apr 12;18(1):412
The lncRNA HOXA11-AS functions as a competing endogenous RNA to regulate PADI2 expression by sponging miR-125a-5p in liver metastasis of colorectal cancer.
Chen D, Sun Q, Zhang L, Zhou X, Cheng X, Zhou D, Ye F, Lin J, Wang W
Oncotarget 2017 Sep 19;8(41):70642-70652
Oncotarget 2017 Sep 19;8(41):70642-70652
PADI2-Mediated Citrullination Promotes Prostate Cancer Progression.
Wang L, Song G, Zhang X, Feng T, Pan J, Chen W, Yang M, Bai X, Pang Y, Yu J, Han J, Han B
Cancer research 2017 Nov 1;77(21):5755-5768
Cancer research 2017 Nov 1;77(21):5755-5768
Role of peptidylarginine deiminase 2 (PAD2) in mammary carcinoma cell migration.
Horibata S, Rogers KE, Sadegh D, Anguish LJ, McElwee JL, Shah P, Thompson PR, Coonrod SA
BMC cancer 2017 May 26;17(1):378
BMC cancer 2017 May 26;17(1):378
Citrullination regulates the expression of insulin-like growth factor-binding protein 1 (IGFBP1) in ovine uterine luminal epithelial cells.
Young CH, Rothfuss HM, Gard PF, Muth A, Thompson PR, Ashley RL, Cherrington BD
Reproduction (Cambridge, England) 2017 Jan;153(1):1-10
Reproduction (Cambridge, England) 2017 Jan;153(1):1-10
Protein-arginine deiminase 2 suppresses proliferation of colon cancer cells through protein citrullination.
Funayama R, Taniguchi H, Mizuma M, Fujishima F, Kobayashi M, Ohnuma S, Unno M, Nakayama K
Cancer science 2017 Apr;108(4):713-718
Cancer science 2017 Apr;108(4):713-718
Downregulation of the Deiminase PADI2 Is an Early Event in Colorectal Carcinogenesis and Indicates Poor Prognosis.
Cantariño N, Musulén E, Valero V, Peinado MA, Perucho M, Moreno V, Forcales SV, Douet J, Buschbeck M
Molecular cancer research : MCR 2016 Sep;14(9):841-8
Molecular cancer research : MCR 2016 Sep;14(9):841-8
A cellular model reflecting the phenotypic heterogeneity of mutant HRAS driven squamous cell carcinoma.
Cantariño N, Fernández-Figueras MT, Valero V, Musulén E, Malinverni R, Granada I, Goldie SJ, Martín-Caballero J, Douet J, Forcales SV, Buschbeck M
International journal of cancer 2016 Sep 1;139(5):1106-16
International journal of cancer 2016 Sep 1;139(5):1106-16
GnRH Stimulates Peptidylarginine Deiminase Catalyzed Histone Citrullination in Gonadotrope Cells.
Khan SA, Edwards BS, Muth A, Thompson PR, Cherrington BD, Navratil AM
Molecular endocrinology (Baltimore, Md.) 2016 Oct;30(10):1081-1091
Molecular endocrinology (Baltimore, Md.) 2016 Oct;30(10):1081-1091
Decreased severity of experimental autoimmune arthritis in peptidylarginine deiminase type 4 knockout mice.
Suzuki A, Kochi Y, Shoda H, Seri Y, Fujio K, Sawada T, Yamada R, Yamamoto K
BMC musculoskeletal disorders 2016 May 5;17:205
BMC musculoskeletal disorders 2016 May 5;17:205
Significant impact of miRNA-target gene networks on genetics of human complex traits.
Okada Y, Muramatsu T, Suita N, Kanai M, Kawakami E, Iotchkova V, Soranzo N, Inazawa J, Tanaka T
Scientific reports 2016 Mar 1;6:22223
Scientific reports 2016 Mar 1;6:22223
Peptidylarginine deiminase 1-catalyzed histone citrullination is essential for early embryo development.
Zhang X, Liu X, Zhang M, Li T, Muth A, Thompson PR, Coonrod SA, Zhang X
Scientific reports 2016 Dec 8;6:38727
Scientific reports 2016 Dec 8;6:38727
Chemical Proteomic Platform To Identify Citrullinated Proteins.
Lewallen DM, Bicker KL, Subramanian V, Clancy KW, Slade DJ, Martell J, Dreyton CJ, Sokolove J, Weerapana E, Thompson PR
ACS chemical biology 2015 Nov 20;10(11):2520-8
ACS chemical biology 2015 Nov 20;10(11):2520-8
Targeted H3R26 deimination specifically facilitates estrogen receptor binding by modifying nucleosome structure.
Guertin MJ, Zhang X, Anguish L, Kim S, Varticovski L, Lis JT, Hager GL, Coonrod SA
PLoS genetics 2014 Sep;10(9):e1004613
PLoS genetics 2014 Sep;10(9):e1004613
PAD2 overexpression in transgenic mice promotes spontaneous skin neoplasia.
McElwee JL, Mohanan S, Horibata S, Sams KL, Anguish LJ, McLean D, Cvitaš I, Wakshlag JJ, Coonrod SA
Cancer research 2014 Nov 1;74(21):6306-17
Cancer research 2014 Nov 1;74(21):6306-17
Identification of macrophage extracellular trap-like structures in mammary gland adipose tissue: a preliminary study.
Mohanan S, Horibata S, McElwee JL, Dannenberg AJ, Coonrod SA
Frontiers in immunology 2013;4:67
Frontiers in immunology 2013;4:67
Potential role for PAD2 in gene regulation in breast cancer cells.
Cherrington BD, Zhang X, McElwee JL, Morency E, Anguish LJ, Coonrod SA
PloS one 2012;7(7):e41242
PloS one 2012;7(7):e41242
Identification of PADI2 as a potential breast cancer biomarker and therapeutic target.
McElwee JL, Mohanan S, Griffith OL, Breuer HC, Anguish LJ, Cherrington BD, Palmer AM, Howe LR, Subramanian V, Causey CP, Thompson PR, Gray JW, Coonrod SA
BMC cancer 2012 Oct 30;12:500
BMC cancer 2012 Oct 30;12:500
ATP induces protein arginine deiminase 2-dependent citrullination in mast cells through the P2X7 purinergic receptor.
Arandjelovic S, McKenney KR, Leming SS, Mowen KA
Journal of immunology (Baltimore, Md. : 1950) 2012 Oct 15;189(8):4112-22
Journal of immunology (Baltimore, Md. : 1950) 2012 Oct 15;189(8):4112-22
Comparative analysis of peptidylarginine deiminase-2 expression in canine, feline and human mammary tumours.
Cherrington BD, Mohanan S, Diep AN, Fleiss R, Sudilovsky D, Anguish LJ, Coonrod SA, Wakshlag JJ
Journal of comparative pathology 2012 Aug-Oct;147(2-3):139-46
Journal of comparative pathology 2012 Aug-Oct;147(2-3):139-46
Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor α target gene activation.
Zhang X, Bolt M, Guertin MJ, Chen W, Zhang S, Cherrington BD, Slade DJ, Dreyton CJ, Subramanian V, Bicker KL, Thompson PR, Mancini MA, Lis JT, Coonrod SA
Proceedings of the National Academy of Sciences of the United States of America 2012 Aug 14;109(33):13331-6
Proceedings of the National Academy of Sciences of the United States of America 2012 Aug 14;109(33):13331-6
Genome-wide analysis reveals PADI4 cooperates with Elk-1 to activate c-Fos expression in breast cancer cells.
Zhang X, Gamble MJ, Stadler S, Cherrington BD, Causey CP, Thompson PR, Roberson MS, Kraus WL, Coonrod SA
PLoS genetics 2011 Jun;7(6):e1002112
PLoS genetics 2011 Jun;7(6):e1002112
Potential role for peptidylarginine deiminase 2 (PAD2) in citrullination of canine mammary epithelial cell histones.
Cherrington BD, Morency E, Struble AM, Coonrod SA, Wakshlag JJ
PloS one 2010 Jul 26;5(7):e11768
PloS one 2010 Jul 26;5(7):e11768
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- BxPC-3 cells were subjected to SDS PAGE followed by western blot with 12110-1-AP(PADI2 antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-PADI2 (IP:12110-1-AP, 3ug; Detection:12110-1-AP 1:300) with mouse brain tissue lysate 8000ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PADI2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PADI2. This antibody recognizes human,mouse,rat antigen. The PADI2 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
