66386-1-Ig

antibody from Proteintech Group

Targeting: PADI2 KIAA0994, PDI2

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

66386-1-Ig

Provider

Proteintech Group

Product name

PADI2 antibody

Antibody type

Monoclonal

Description

KD/KO validated PADI2 antibody (Cat. #66386-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat, rabbit, pig and has been validated for the following applications: IF, IHC, WB,ELISA.

Reactivity

Human, Mouse, Rat, Porcine, Rabbit

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

2D8C12

Vial size

20ul, 150ul

References

Submitted references

Fuhu Lijie Tang treats rheumatoid arthritis through multitarget therapy from autoantigen formation to bone destruction.

Yao Z, He J, Hu M, Yan P, Xu Q, Zhang Q, Lin Y, Liao J, Cai X, Liu L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157086

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Citrullinated ENO1 Vaccine Enhances PD-1 Blockade in Mice Implanted with Murine Triple-Negative Breast Cancer Cells.

León-Letelier RA, Sevillano-Mantas AM, Chen Y, Park S, Vykoukal J, Fahrmann JF, Ostrin EJ, Garrett C, Dou R, Cai Y, Hsiao FC, Dennison JB, Vilar E, Arun BK, Hanash S, Katayama H
Vaccines 2025 Jun 11;13(6)

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Quantitative evaluation of citrullinated fibrinogen for detection of neutrophil extracellular traps.

Sue T, Ichikawa T, Hattori S, Otani H, Fujimura S, Higuchi T, Okumura N, Higuchi Y
Immunologic research 2024 Jun;72(3):409-417

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Small molecule activates citrullination through targeting PAD2.

Zhang X, Shen M, Zhu H, Zhang J, Yang M, Su K, Zhang Y, Fu W, Ke X, Qu Y
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2023 Nov 20;378(1890):20220248

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Peptidylarginine deiminase 2 plays a key role in osteogenesis by enhancing RUNX2 stability through citrullination.

Kim HJ, Shin HR, Yoon H, Park MS, Kim BG, Moon JI, Kim WJ, Park SG, Kim KT, Kim HN, Choi JY, Ryoo HM
Cell death & disease 2023 Aug 30;14(8):576

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Cholinergic dysfunction-induced insufficient activation of alpha7 nicotinic acetylcholine receptor drives the development of rheumatoid arthritis through promoting protein citrullination via the SP3/PAD4 pathway.

Lv C, Sun M, Guo Y, Xia W, Qiao S, Tao Y, Fang Y, Zhang Q, Zhu Y, Yalikun Y, Xia Y, Wei Z, Dai Y
Acta pharmaceutica Sinica. B 2023 Apr;13(4):1600-1615

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ROS-induced PADI2 downregulation accelerates cellular senescence via the stimulation of SASP production and NFκB activation.

Kim HJ, Kim WJ, Shin HR, Yoon HI, Moon JI, Lee E, Lim JM, Cho YD, Lee MH, Kim HG, Ryoo HM
Cellular and molecular life sciences : CMLS 2022 Feb 26;79(3):155

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Protein citrullination as a source of cancer neoantigens.

Katayama H, Kobayashi M, Irajizad E, Sevillarno A, Patel N, Mao X, Rusling L, Vykoukal J, Cai Y, Hsiao F, Yu CY, Long J, Liu J, Esteva F, Fahrmann J, Hanash S
Journal for immunotherapy of cancer 2021 Jun;9(6)

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Changes in the Oligodendrocyte Progenitor Cell Proteome with Ageing.

de la Fuente AG, Queiroz RML, Ghosh T, McMurran CE, Cubillos JF, Bergles DE, Fitzgerald DC, Jones CA, Lilley KS, Glover CP, Franklin RJM
Molecular & cellular proteomics : MCP 2020 Aug;19(8):1281-1302