Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [5]
- Flow cytometry [1]
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Validation data
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- Product number
- NBP2-47745-0.1mg - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal Cadherin-16 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified. This MAb recognizes a protein of 130kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
- Reactivity
- Human, Mouse, Rat, Canine, Rabbit
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Cadherin-16 Antibody (CDH16/1071) - Azide and BSA Free [NBP2-47745] - Analysis of human kidney tissue lysate usingCadherin-16 Antibody (CDH16/1071).
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Cadherin-16 Antibody (CDH16/1071) - Azide and BSA Free [NBP2-47745] - Rat Kidney stained with KSP-Cadherin Monoclonal Antibody (CDH16/1071)
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Cadherin-16 Antibody (CDH16/1071) - Azide and BSA Free [NBP2-47745] - Mouse Kidney stained with Cadherin-16 Antibody (CDH16/1071).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Cadherin-16 Antibody (CDH16/1071) - Azide and BSA Free [NBP2-47745] - Human Kidney stained with Cadherin-16 Antibody (CDH16/1071) followed by Goat anti-Mouse IgG-CF640R (Purple)
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Cadherin-16 Antibody (CDH16/1071) - Azide and BSA Free [NBP2-47745] - Human Renal Cell Carcinoma stained with KSP-Cadherin Monoclonal Antibody (CDH16/1071)
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Cadherin-16 Antibody (CDH16/1071) - Azide and BSA Free [NBP2-47745] - Human Kidney stained with Cadherin-16 Antibody (CDH16/1071).
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: Cadherin-16 Antibody (CDH16/1071) - Azide and BSA Free [NBP2-47745] - Analysis of human HEK293 cells usingCadherin-16 Antibody (CDH16/1071) followed by Goat anti-Mouse IgG-CF488 (Blue); Isotype Control (Red).