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- Antibody Data
- Antigen structure
- References [8]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 21620-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21620-1-AP, RRID:AB_10858623
- Product name
- TMED9 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TMED9 antibody (Cat. #21620-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat, pig and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The p24-family and COPII subunit SEC24C facilitate the clearance of alpha1-antitrypsin Z from the endoplasmic reticulum to lysosomes.
A new type of ERGIC-ERES membrane contact mediated by TMED9 and SEC12 is required for autophagosome biogenesis.
Screening of the novel immune-suppressive biomarkers of TMED family and whether knockdown of TMED2/3/4/9 inhibits cell migration and invasion in breast cancer.
TMED3 Complex Mediates ER Stress-Associated Secretion of CFTR, Pendrin, and SARS-CoV-2 Spike.
ACBD3 modulates KDEL receptor interaction with PKA for its trafficking via tubulovesicular carrier.
High expression of transmembrane P24 trafficking protein 9 predicts poor prognosis in breast carcinoma.
A Translocation Pathway for Vesicle-Mediated Unconventional Protein Secretion.
Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy.
Roberts BS, Mitra D, Abishek S, Beher R, Satpute-Krishnan P
Molecular biology of the cell 2024 Mar 1;35(3):ar45
Molecular biology of the cell 2024 Mar 1;35(3):ar45
A new type of ERGIC-ERES membrane contact mediated by TMED9 and SEC12 is required for autophagosome biogenesis.
Li S, Yan R, Xu J, Zhao S, Ma X, Sun Q, Zhang M, Li Y, Liu JG, Chen L, Li S, Xu K, Ge L
Cell research 2022 Feb;32(2):119-138
Cell research 2022 Feb;32(2):119-138
Screening of the novel immune-suppressive biomarkers of TMED family and whether knockdown of TMED2/3/4/9 inhibits cell migration and invasion in breast cancer.
Fang Z, Song YX, Wo GQ, Zhou HL, Li L, Yang SY, Chen X, Zhang J, Tang JH
Annals of translational medicine 2022 Dec;10(23):1280
Annals of translational medicine 2022 Dec;10(23):1280
TMED3 Complex Mediates ER Stress-Associated Secretion of CFTR, Pendrin, and SARS-CoV-2 Spike.
Park H, Seo SK, Sim JR, Hwang SJ, Kim YJ, Shin DH, Jang DG, Noh SH, Park PG, Ko SH, Shin MH, Choi JY, Ito Y, Kang CM, Lee JM, Lee MG
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Aug;9(24):e2105320
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Aug;9(24):e2105320
ACBD3 modulates KDEL receptor interaction with PKA for its trafficking via tubulovesicular carrier.
Yue X, Qian Y, Zhu L, Gim B, Bao M, Jia J, Jing S, Wang Y, Tan C, Bottanelli F, Ziltener P, Choi S, Hao P, Lee I
BMC biology 2021 Sep 7;19(1):194
BMC biology 2021 Sep 7;19(1):194
High expression of transmembrane P24 trafficking protein 9 predicts poor prognosis in breast carcinoma.
Ju G, Xu C, Zeng K, Zhou T, Zang L
Bioengineered 2021 Dec;12(1):8965-8979
Bioengineered 2021 Dec;12(1):8965-8979
A Translocation Pathway for Vesicle-Mediated Unconventional Protein Secretion.
Zhang M, Liu L, Lin X, Wang Y, Li Y, Guo Q, Li S, Sun Y, Tao X, Zhang D, Lv X, Zheng L, Ge L
Cell 2020 Apr 30;181(3):637-652.e15
Cell 2020 Apr 30;181(3):637-652.e15
Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy.
Dvela-Levitt M, Kost-Alimova M, Emani M, Kohnert E, Thompson R, Sidhom EH, Rivadeneira A, Sahakian N, Roignot J, Papagregoriou G, Montesinos MS, Clark AR, McKinney D, Gutierrez J, Roth M, Ronco L, Elonga E, Carter TA, Gnirke A, Melanson M, Hartland K, Wieder N, Hsu JC, Deltas C, Hughey R, Bleyer AJ, Kmoch S, Živná M, Barešova V, Kota S, Schlondorff J, Heiman M, Alper SL, Wagner F, Weins A, Golub TR, Lander ES, Greka A
Cell 2019 Jul 25;178(3):521-535.e23
Cell 2019 Jul 25;178(3):521-535.e23
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse liver tissue were subjected to SDS PAGE followed by western blot with 21620-1-AP(TMED9 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using TMED9 antibody 21620-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 21620-1-AP(TMED9 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 21620-1-AP(TMED9 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
