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- References [12]
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- Product number
- 18370-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18370-1-AP, RRID:AB_10858633
- Product name
- Orexin receptor 1 antibody
- Antibody type
- Polyclonal
- Description
- Orexin receptor 1 antibody (Cat. #18370-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Neuroprotective Effects of Transcranial Pulsed Current Stimulation: Modulation of Microglial Polarization in Traumatic Brain Injury.
Orexin A alleviates chronic cerebral hypoperfusion-induced neuroinflammation and cognitive dysfunction by inhibiting the NEK7/NLRP3 pathway.
Discovery, asymmetric synthesis and biological evaluation of new bisbenzylisoquinoline-orexin receptor antagonists for insomnia treatment.
Transcranial pulsed current stimulation alleviates neuronal pyroptosis and neurological dysfunction following traumatic brain injury via the orexin-A/NLRP3 pathway.
Generation of locus coeruleus norepinephrine neurons from human pluripotent stem cells.
Hypocretin-1/Hypocretin Receptor 1 Regulates Neuroplasticity and Cognitive Function through Hippocampal Lactate Homeostasis in Depressed Model.
Analgesic effect of linalool odor on oral ulcerative mucositis-induced pain in rats.
Orexin-A/OX1R is involved in regulation of autophagy to promote cortisol secretion in adrenocortical cell.
Orexin-A Reverse Bone Mass Loss Induced by Chronic Intermittent Hypoxia Through OX1R-Nrf2/HIF-1α Pathway.
The Ciji-Hua'ai-Baosheng II Formula Attenuates Chemotherapy-Induced Anorexia in Mice With H(22) Hepatocellular Carcinoma.
Aerobic training associated with an active lifestyle exerts a protective effect against oxidative damage in hypothalamus and liver: The involvement of energy metabolism.
Soporific Effect of Modified Suanzaoren Decoction and Its Effects on the Expression of CCK-8 and Orexin-A.
Yao P, Ren B, Zhou Q, Bai Y, Feng Z
CNS neuroscience & therapeutics 2025 Sep;31(9):e70606
CNS neuroscience & therapeutics 2025 Sep;31(9):e70606
Orexin A alleviates chronic cerebral hypoperfusion-induced neuroinflammation and cognitive dysfunction by inhibiting the NEK7/NLRP3 pathway.
Chen Y, Zhou Q, Su L, Zhao Y, Xing X, Yao P
Experimental neurology 2025 Nov;393:115378
Experimental neurology 2025 Nov;393:115378
Discovery, asymmetric synthesis and biological evaluation of new bisbenzylisoquinoline-orexin receptor antagonists for insomnia treatment.
Fang J, Wang Y, He J, Ge C, Zhang Y, Liu Y, Jiang Y, Liu S
European journal of medicinal chemistry 2025 Nov 5;297:117957
European journal of medicinal chemistry 2025 Nov 5;297:117957
Transcranial pulsed current stimulation alleviates neuronal pyroptosis and neurological dysfunction following traumatic brain injury via the orexin-A/NLRP3 pathway.
Yao P, Zhou Q, Ren B, Yang L, Bai Y, Feng Z
Neuropeptides 2025 Mar;110:102501
Neuropeptides 2025 Mar;110:102501
Generation of locus coeruleus norepinephrine neurons from human pluripotent stem cells.
Tao Y, Li X, Dong Q, Kong L, Petersen AJ, Yan Y, Xu K, Zima S, Li Y, Schmidt DK, Ayala M, Mathivanan S, Sousa AMM, Chang Q, Zhang SC
Nature biotechnology 2024 Sep;42(9):1404-1416
Nature biotechnology 2024 Sep;42(9):1404-1416
Hypocretin-1/Hypocretin Receptor 1 Regulates Neuroplasticity and Cognitive Function through Hippocampal Lactate Homeostasis in Depressed Model.
Chen B, Jin K, Dong J, Cheng S, Kong L, Hu S, Chen Z, Lu J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Oct;11(38):e2405354
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Oct;11(38):e2405354
Analgesic effect of linalool odor on oral ulcerative mucositis-induced pain in rats.
Iida M, Hitomi S, Hayashi Y, Shibuta I, Tsuboi Y, Ueda K, Iwata K, Shinoda M
Brain research bulletin 2024 Jan;206:110844
Brain research bulletin 2024 Jan;206:110844
Orexin-A/OX1R is involved in regulation of autophagy to promote cortisol secretion in adrenocortical cell.
Guo X, Wen J, Gao Q, Zhao Y, Zhao Y, Wang C, Xu N, Shao Y, Chang X
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166844
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166844
Orexin-A Reverse Bone Mass Loss Induced by Chronic Intermittent Hypoxia Through OX1R-Nrf2/HIF-1α Pathway.
Gu H, Ru Y, Wang W, Cai G, Gu L, Ye J, Zhang WB, Wang L
Drug design, development and therapy 2022;16:2145-2160
Drug design, development and therapy 2022;16:2145-2160
The Ciji-Hua'ai-Baosheng II Formula Attenuates Chemotherapy-Induced Anorexia in Mice With H(22) Hepatocellular Carcinoma.
Xi S, Zhai X, Wang Y, Gong Y, Fu B, Gao C, Guo X, Li Y, Wang Z, Huang S, Lu D, Zhao Y, Qian L, Wang Y
Frontiers in pharmacology 2021;12:715824
Frontiers in pharmacology 2021;12:715824
Aerobic training associated with an active lifestyle exerts a protective effect against oxidative damage in hypothalamus and liver: The involvement of energy metabolism.
Scariot PPM, Manchado-Gobatto FB, Van Ginkel PR, Prolla TA, Gobatto CA
Brain research bulletin 2021 Oct;175:116-129
Brain research bulletin 2021 Oct;175:116-129
Soporific Effect of Modified Suanzaoren Decoction and Its Effects on the Expression of CCK-8 and Orexin-A.
Zhan LH, Dong YJ, Yang K, Lei SS, Li B, Teng X, Zhou C, Luo R, Yu QX, Jin HY, Lv GY, Chen SH
Evidence-based complementary and alternative medicine : eCAM 2020;2020:6984087
Evidence-based complementary and alternative medicine : eCAM 2020;2020:6984087
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Orexin receptor 1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human Orexin receptor 1. This antibody recognizes human,mouse,rat antigen. The Orexin receptor 1 antibody has been validated for the following applications: ELISA, WB analysis.
