27567-1-AP

antibody from Proteintech Group

Targeting: GABBR2 GABABR2, GPR51, GPRC3B, HG20

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

27567-1-AP

Provider

Proteintech Group

Product name

GABBR2 antibody

Antibody type

Polyclonal

Description

GABBR2 antibody (Cat. #27567-1-AP) is a rabbit polyclonal antibody that shows reactivity with Human, Mouse, Rat and has been validated for the following applications: IHC, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Neuropeptide SP protects against colitis and linked anxiety-like behavior through the putative roles of gut microbiota and metabolite inositol.

Lan J, Wang J, Huang S, Li C, Deng Z, Hao Z, Ma Y
Nature communications 2026 Jan 8;17(1):295

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Jujuboside A in ameliorating insomnia in mice via GABAergic modulation of the PVT.

Wang M, Wang G, Zhao M, Hou L, Ma D, Yang H, Luo Z, Mi B, Lv S
Journal of ethnopharmacology 2025 Jun 12;349:119939

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Intervention in gut microbiota increases intestinal γ-aminobutyric acid and alleviates anxiety behavior: a possible mechanism via the action on intestinal epithelial cells.

Ikegami M, Narabayashi H, Nakata K, Yamashita M, Sugi Y, Fuji Y, Matsufuji H, Harata G, Yoda K, Miyazawa K, Nakanishi Y, Takahashi K
Frontiers in cellular and infection microbiology 2024;14:1421791

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Activation of GABA(B)R Attenuates Intestinal Inflammation by Reducing Oxidative Stress through Modulating the TLR4/MyD88/NLRP3 Pathway and Gut Microbiota Abundance.

Deng Z, Li D, Wang L, Lan J, Wang J, Ma Y
Antioxidants (Basel, Switzerland) 2024 Sep 21;13(9)

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Activation of nuclear receptor pregnane-X-receptor protects against abdominal aortic aneurysm by inhibiting oxidative stress.

Shen Z, Wang J, Chen Y, Fang P, Yuan A, Chen AF, Yan X, Lyu Y, Pu J
Redox biology 2024 Nov;77:103397

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GABA(B) modulate NF-κB/NLRP3 pathways in electroacupuncture prevention of depression in CUMS rats.

Li J, Yao D, Zhang T, Tong T, Shen J, Yan S, Zeng J, Aslam MS, Li M, You Z, Li J, Li Z, Li Y, Hao C, Meng X
Brain research bulletin 2024 Nov;218:111108

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Paeonol and glycyrrhizic acid in combination ameliorate the recurrent nitroglycerin-induced migraine-like phenotype in rats by regulating the GABBR2/TRPM8/PRKACA/TRPV1 pathway.

Zhang Y, Ge F, Luo Y, Ji X, Liu Z, Qiu Y, Hou J, Zhou R, Zhao C, Xu Q, Zhang S, Yu X, Wang C, Ge D, Meng F, Tao X
Journal of ethnopharmacology 2024 Nov 15;334:118464

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Metabolomics-Based Effects of a Natural Product on Remyelination After Cerebral Ischemia Injury Via GABABR-pCREB-BDNF Pathway.

Fan X, Zhan M, Song W, Yao M, Wang G, Li T, Zhang Y, Liu J
Neurorehabilitation and neural repair 2024 May;38(5):350-363

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Impact of Abl2/Arg deficiency on anxiety and depressive behaviors in mice.

Yao X, Chen R, Chen H, Koleske A, Xiao X
Behavioural brain research 2024 Jun 25;468:115022

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1,2-Dichloroethane causes anxiety and cognitive dysfunction in mice by disturbing GABA metabolism and inhibiting the cAMP-PKA-CREB signaling pathway.

Qin Y, Huang W, Wang Z, Wang C, Wang C, Zhang M, Wu S, Wang G, Zhao F
Ecotoxicology and environmental safety 2024 Jul 1;279:116464

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Peanut oil odor enhances the immunomodulatory effect on immunosuppressed mice by regulating the cAMP signaling pathway via the brain-spleen axis.

Wang Y, Wu J, Gong Y, Wang H, Wu T, Liu R, Sui W, Zhang M
Food & function 2024 Feb 19;15(4):1994-2007

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GAD1-mediated GABA elicits aggressive characteristics of human oral cancer cells.

Dou Z, Li M, Shen Z, Jiang H, Pang X, Li T, Liang X, Tang Y
Biochemical and biophysical research communications 2023 Nov 12;681:80-89

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γ-aminobutyric acid B2 receptor: A potential therapeutic target for cholangiocarcinoma in patients with diabetes mellitus.

Saengboonmee C, Sorin S, Sangkhamanon S, Chomphoo S, Indramanee S, Seubwai W, Thithuan K, Chiu CF, Okada S, Gingras MC, Wongkham S
World journal of gastroenterology 2023 Jul 28;29(28):4416-4432

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GABA regulates the proliferation and apoptosis of head and neck squamous cell carcinoma cells by promoting the expression of CCND2 and BCL2L1.

Luo K, Zhao X, Shan Y, Wang X, Xu Y, Chen M, Wang Q, Song Y
Life sciences 2023 Dec 1;334:122191

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Cancer-cell-derived GABA promotes β-catenin-mediated tumour growth and immunosuppression.

Huang D, Wang Y, Thompson JW, Yin T, Alexander PB, Qin D, Mudgal P, Wu H, Liang Y, Tan L, Pan C, Yuan L, Wan Y, Li QJ, Wang XF
Nature cell biology 2022 Feb;24(2):230-241