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- References [14]
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- Immunohistochemistry [2]
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- Product number
- 19716-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19716-1-AP, RRID:AB_10642009
- Product name
- PYGM-Specific antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PYGM-Specific antibody (Cat. #19716-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references An artificial cell capable of signal transduction mediated by ADRB2 for the regulation of glycogenolysis.
Machine learning identifies PYGM as a macrophage polarization-linked metabolic biomarker in rectal cancer prognosis.
Identify of blood glucose metabolism regulation pathways and related proteins in the db/db mouse model through iTRAQ quantitative mass spectrometry.
Multi-layered transcriptional control of glycogen metabolism coordinates thermogenic remodeling of white adipocytes in male mice.
Identification of disease-specific extracellular vesicle-associated plasma protein biomarkers for Duchenne Muscular Dystrophy and Facioscapulohumeral Muscular Dystrophy.
Proteomic profiling of polyglucosan bodies associated with glycogenin-1 deficiency in skeletal muscle.
Circular RNA circMYLK4 shifts energy metabolism from glycolysis to OXPHOS by binding to the calcium channel auxiliary subunit CACNA2D2.
PYGL-mediated glucose metabolism reprogramming promotes EMT phenotype and metastasis of pancreatic cancer.
Glycolytic enzyme PFKFB3 regulates sphingosine 1-phosphate receptor 1 in proangiogenic glomerular endothelial cells under diabetic condition.
Proteomic Landscape and Deduced Functions of the Cardiac 14-3-3 Protein Interactome.
Analysis of the expression, function and signaling of glycogen phosphorylase isoforms in hepatocellular carcinoma.
Glycogen metabolism links glucose homeostasis to thermogenesis in adipocytes.
The different expression of glycogen phosphorylases in renal clear cell renal carcinoma and chromophobe renal carcinoma.
Absence of p.R50X Pygm read-through in McArdle disease cellular models.
Liu Y, Zhao W, Zhao Y, Zhang X, Zhao J, Li S, Ren Y, Han X
Nature communications 2026 Jan 16;17(1):1795
Nature communications 2026 Jan 16;17(1):1795
Machine learning identifies PYGM as a macrophage polarization-linked metabolic biomarker in rectal cancer prognosis.
Xu C, Zhang S, Sun B, Yu Z, Liu H
Frontiers in immunology 2025;16:1639303
Frontiers in immunology 2025;16:1639303
Identify of blood glucose metabolism regulation pathways and related proteins in the db/db mouse model through iTRAQ quantitative mass spectrometry.
Yue Y, Dong S, Wu Z, Dong Y, Chen Q, Wang H, Liu C, Yang D
Acta diabetologica 2025 Sep;62(9):1417-1428
Acta diabetologica 2025 Sep;62(9):1417-1428
Multi-layered transcriptional control of glycogen metabolism coordinates thermogenic remodeling of white adipocytes in male mice.
Fu H, Lee S, Zemke NR, Fan W, Wang Y, Garza J, Tin D, Villao B, Zhang B, Ma X, Zhang J, Dong T, Ren Y, Downes M, Evans RM, Ren B, Saltiel AR
Nature communications 2025 Dec 16;17(1):809
Nature communications 2025 Dec 16;17(1):809
Identification of disease-specific extracellular vesicle-associated plasma protein biomarkers for Duchenne Muscular Dystrophy and Facioscapulohumeral Muscular Dystrophy.
Bayazit MB, Henderson D, Nguyen KT, Reátegui E, Tawil R, Flanigan KM, Harper SQ, Saad NY
medRxiv : the preprint server for health sciences 2024 Nov 30;
medRxiv : the preprint server for health sciences 2024 Nov 30;
Proteomic profiling of polyglucosan bodies associated with glycogenin-1 deficiency in skeletal muscle.
Visuttijai K, Hedberg-Oldfors C, Costello DJ, Bermingham N, Oldfors A
Neuropathology and applied neurobiology 2024 Jun;50(3):e12995
Neuropathology and applied neurobiology 2024 Jun;50(3):e12995
Circular RNA circMYLK4 shifts energy metabolism from glycolysis to OXPHOS by binding to the calcium channel auxiliary subunit CACNA2D2.
Cao H, Li C, Sun X, Yang J, Li X, Yang G, Jin J, Shi X
The Journal of biological chemistry 2024 Jul;300(7):107426
The Journal of biological chemistry 2024 Jul;300(7):107426
PYGL-mediated glucose metabolism reprogramming promotes EMT phenotype and metastasis of pancreatic cancer.
Ji Q, Li H, Cai Z, Yuan X, Pu X, Huang Y, Fu S, Chu L, Jiang C, Xue J, Zhang X, Li R
International journal of biological sciences 2023;19(6):1894-1909
International journal of biological sciences 2023;19(6):1894-1909
Glycolytic enzyme PFKFB3 regulates sphingosine 1-phosphate receptor 1 in proangiogenic glomerular endothelial cells under diabetic condition.
Yu B, Shen K, Li T, Li J, Meng M, Liu W, Tang Q, Zhu T, Wang X, Leung SWS, Shi Y
American journal of physiology. Cell physiology 2023 Nov 1;325(5):C1354-C1368
American journal of physiology. Cell physiology 2023 Nov 1;325(5):C1354-C1368
Proteomic Landscape and Deduced Functions of the Cardiac 14-3-3 Protein Interactome.
Qu JH, Tarasov KV, Chakir K, Tarasova YS, Riordon DR, Lakatta EG
Cells 2022 Nov 4;11(21)
Cells 2022 Nov 4;11(21)
Analysis of the expression, function and signaling of glycogen phosphorylase isoforms in hepatocellular carcinoma.
Jiang L, Liu S, Deng T, Yang Y, Zhang Y
Oncology letters 2022 Aug;24(2):244
Oncology letters 2022 Aug;24(2):244
Glycogen metabolism links glucose homeostasis to thermogenesis in adipocytes.
Keinan O, Valentine JM, Xiao H, Mahata SK, Reilly SM, Abu-Odeh M, Deluca JH, Dadpey B, Cho L, Pan A, Yu RT, Dai Y, Liddle C, Downes M, Evans RM, Lusis AJ, Laakso M, Chouchani ET, Rydén M, Saltiel AR
Nature 2021 Nov;599(7884):296-301
Nature 2021 Nov;599(7884):296-301
The different expression of glycogen phosphorylases in renal clear cell renal carcinoma and chromophobe renal carcinoma.
Lu Y, Luo G, Zhu S, Wang X, Chen Y, Dong Z, Wang S, Ma J, Deng H, Wu D, Dong J
Clinical proteomics 2020;17:7
Clinical proteomics 2020;17:7
Absence of p.R50X Pygm read-through in McArdle disease cellular models.
Tarrasó G, Real-Martinez A, Parés M, Romero-Cortadellas L, Puigros L, Moya L, de Luna N, Brull A, Martín MA, Arenas J, Lucia A, Andreu AL, Barquinero J, Vissing J, Krag TO, Pinós T
Disease models & mechanisms 2020 Jan 13;13(1)
Disease models & mechanisms 2020 Jan 13;13(1)
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 19716-1-AP(PYGM-Specific antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human skeletal muscle using 19716-1-AP(PYGM-Specific antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PYGM-Specific antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human PYGM-Specific. This antibody recognizes human, mouse, rat antigen. The PYGM-Specific antibody has been validated for the following applications: ELISA, WB, IHC analysis.
