Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [2]
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Validation data
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- Product number
- NB600-836 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB600-836, RRID:AB_10003094
- Product name
- Sheep Polyclonal EDNRA/Endothelin R Type A Antibody
- Antibody type
- Polyclonal
- Description
- Protein G purified. This recognizes epitopes on the cytoplasmic side of the receptor and will not block the binding of endothelins. Therefore, the cell membrane must be permeable to the.
- Reactivity
- Mouse
- Host
- Sheep
- Isotype
- IgG
- Vial size
- 0.125 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Endothelin-1 mediated induction of extracellular matrix genes in strial marginal cells underlies strial pathology in Alport mice.
Endothelin A receptor activation on mesangial cells initiates Alport glomerular disease.
Estrogen and progesterone regulate expression of the endothelins in the rhesus macaque endometrium.
BMPR2 mutation alters the lung macrophage endothelin-1 cascade in a mouse model and patients with heritable pulmonary artery hypertension.
Meehan DT, Delimont D, Dufek B, Zallocchi M, Phillips G, Gratton MA, Cosgrove D
Hearing research 2016 Nov;341:100-108
Hearing research 2016 Nov;341:100-108
Endothelin A receptor activation on mesangial cells initiates Alport glomerular disease.
Dufek B, Meehan DT, Delimont D, Cheung L, Gratton MA, Phillips G, Song W, Liu S, Cosgrove D
Kidney international 2016 Aug;90(2):300-310
Kidney international 2016 Aug;90(2):300-310
Estrogen and progesterone regulate expression of the endothelins in the rhesus macaque endometrium.
Keator CS, Mah K, Ohm L, Slayden OD
Human reproduction (Oxford, England) 2011 Jul;26(7):1715-28
Human reproduction (Oxford, England) 2011 Jul;26(7):1715-28
BMPR2 mutation alters the lung macrophage endothelin-1 cascade in a mouse model and patients with heritable pulmonary artery hypertension.
Talati M, West J, Blackwell TR, Loyd JE, Meyrick B
American journal of physiology. Lung cellular and molecular physiology 2010 Sep;299(3):L363-73
American journal of physiology. Lung cellular and molecular physiology 2010 Sep;299(3):L363-73
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: EDNRA/Endothelin R Type A Antibody [NB600-836] - ET-1 A & B Receptor Western provided by verified customer review.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: EDNRA/Endothelin R Type A Antibody [NB600-836] - EDN 1 Receptor A in 1 MES Cells. Western Provided by verified customer review.