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- References [4]
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- Product number
- 21465-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21465-1-AP, RRID:AB_10734429
- Product name
- IGSF21 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated IGSF21 antibody (Cat. #21465-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Structural and functional characterization of the IgSF21-neurexin2α complex and its related signaling pathways in the regulation of inhibitory synapse organization.
IgLON5 deficiency produces behavioral alterations in a knockout mouse model.
Patients' IgLON5 autoantibodies interfere with IgLON5-protein interactions.
IgSF21 promotes differentiation of inhibitory synapses via binding to neurexin2α.
Chofflet N, Naito Y, Pastore AJ, Padmanabhan N, Nguyen PT, Poitras C, Feller B, Yi N, Van Prooijen J, Khaled H, Coulombe B, Clapcote SJ, Bourgault S, Siddiqui TJ, Rudenko G, Takahashi H
Frontiers in molecular neuroscience 2024;17:1371145
Frontiers in molecular neuroscience 2024;17:1371145
IgLON5 deficiency produces behavioral alterations in a knockout mouse model.
Landa J, Serafim AB, Alba M, Maudes E, Molina-Porcel L, Garcia-Serra A, Mannara F, Dalmau J, Graus F, Sabater L
Frontiers in immunology 2024;15:1347948
Frontiers in immunology 2024;15:1347948
Patients' IgLON5 autoantibodies interfere with IgLON5-protein interactions.
Landa J, Serafim AB, Gaig C, Saiz A, Koneczny I, Hoftberger R, Santamaria J, Dalmau J, Graus F, Sabater L
Frontiers in immunology 2023;14:1151574
Frontiers in immunology 2023;14:1151574
IgSF21 promotes differentiation of inhibitory synapses via binding to neurexin2α.
Tanabe Y, Naito Y, Vasuta C, Lee AK, Soumounou Y, Linhoff MW, Takahashi H
Nature communications 2017 Sep 1;8(1):408
Nature communications 2017 Sep 1;8(1):408
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Supportive validation
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- Proteintech Group (provider)
- Main image
- Experimental details
- The IGSF21 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human IGSF21. This antibody recognizes human, mouse, rat antigen. The IGSF21 antibody has been validated for the following applications: ELISA, WB analysis.
