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- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- BS61198 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- GTPBP5 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human GTPBP5.
- Description
- Small G proteins act as molecular switches for regulation of variety of cellular processes, such as nuclear transport, signal transduction, membrane trafficking and protein synthesis. GTPBP5 (GTP-binding protein 5), also known as OBGH1, is a 406 amino acid small G protein that contains an amino-terminal mitochondria-localization signal. Knockdown of GTPBP5 mRNA results in abnormal nuclear morphologies and elongated mitochondria. In vitro studies demonstrate that GTPBP5 exhibits GTPase activity, cycling between an active GTP-bound state and an inactive GDP-bound state. Activation of GTPases usually results in rearrangements of filamentous actin and the formation of actin stress fibers.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- Western blot (WB) analysis of GTPBP5 pAb at 1:500 dilution Line1:A549 whole cell lysateLine2:Hela whole cell lysateLine3:PC12 whole cell lysateLine4:sp20 whole cell lysate
