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- Antigen structure
- References [19]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 18505-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- CYP1B1 antibody
- Antibody type
- Polyclonal
- Description
- CYP1B1 antibody (Cat. #18505-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Human neural stem cells promote mitochondrial genesis to alleviate neuronal damage in MPTP-induced cynomolgus monkey models.
Intracellular tacrolimus concentration correlates with impaired renal function through regulation of the IS-AHR-ABC transporter in peripheral blood mononuclear cells.
Regulation of Benzo[a]pyrene-Induced Hepatic Lipid Accumulation through CYP1B1-Induced mTOR-Mediated Lipophagy.
Myeloid cell-associated aromatic amino acid metabolism facilitates CNS myelin regeneration.
Estrogen genotoxicity causes preferential development of Fuchs endothelial corneal dystrophy in females.
Jujuboside A Attenuates Polycystic Ovary Syndrome Based on Estrogen Metabolism Through Activating AhR-mediated CYP1A2 Expression.
Therapeutic effects of inĀ vivo administration of an inhibitor of tryptophan 2,3-dioxygenase (680c91) for the treatment of fibroids: a preclinical study.
Qi Gong Wan ameliorates adipocyte hypertrophy and inflammation in adipose tissue in a PCOS mouse model through the Nrf2/HO-1/Cyp1b1 pathway: Integrating network pharmacology and experimental validation in vivo.
CYP1B1 promotes colorectal cancer liver metastasis by enhancing the growth of metastatic cancer cells via a fatty acids-dependent manner.
Astilbin Activates the Reactive Oxidative Species/PPARĪ³ Pathway to Suppress Effector CD4(+) T Cell Activities via Direct Binding With Cytochrome P450 1B1.
NUPR1 contributes to radiation resistance by maintaining ROS homeostasis via AhR/CYP signal axis in hepatocellular carcinoma.
CYP1B1: A Novel Molecular Biomarker Predicts Molecular Subtype, Tumor Microenvironment, and Immune Response in 33 Cancers.
piRNA-14633 promotes cervical cancer cell malignancy in a METTL14-dependent m6A RNA methylation manner.
Reduced IRF4 expression promotes lytic phenotype in Type 2 EBV-infected B cells.
PET-CT and RNA sequencing reveal novel targets for acupuncture-induced lowering of blood pressure in spontaneously hypertensive rats.
Sensing the Generation of Intracellular Free Electrons Using the Inactive Catalytic Subunit of Cytochrome P450s as a Sink.
Ocular Ciliopathies: Genetic and Mechanistic Insights into Developing Therapies.
Role of the aryl hydrocarbon receptor signaling pathway in promoting mitochondrial biogenesis against oxidative damage in human melanocytes.
CYP enzymes, expressed within live human suspension cells, are superior to widely-used microsomal enzymes in identifying potent CYP1A1/CYP1B1 inhibitors: Identification of quinazolinones as CYP1A1/CYP1B1 inhibitors that efficiently reverse B[a]P toxicity and cisplatin resistance.
He Y, Li R, Yu Y, Huang C, Xu Z, Wang T, Chen M, Huang H, Qi Z
Neurochemistry international 2024 May;175:105700
Neurochemistry international 2024 May;175:105700
Intracellular tacrolimus concentration correlates with impaired renal function through regulation of the IS-AHR-ABC transporter in peripheral blood mononuclear cells.
Guo P, Zhang R, Zhou J, Li P, Liu Y, Shi S
International immunopharmacology 2024 Jan 5;126:111233
International immunopharmacology 2024 Jan 5;126:111233
Regulation of Benzo[a]pyrene-Induced Hepatic Lipid Accumulation through CYP1B1-Induced mTOR-Mediated Lipophagy.
Bu KB, Kim M, Shin MK, Lee SH, Sung JS
International journal of molecular sciences 2024 Jan 22;25(2)
International journal of molecular sciences 2024 Jan 22;25(2)
Myeloid cell-associated aromatic amino acid metabolism facilitates CNS myelin regeneration.
Hu J, Melchor GS, Ladakis D, Reger J, Kim HW, Chamberlain KA, Shults NV, Oft HC, Smith VN, Rosko LM, Li E, Baydyuk M, Fu MM, Bhargava P, Huang JK
NPJ Regenerative medicine 2024 Jan 2;9(1):1
NPJ Regenerative medicine 2024 Jan 2;9(1):1
Estrogen genotoxicity causes preferential development of Fuchs endothelial corneal dystrophy in females.
Kumar V, Deshpande N, Parekh M, Wong R, Ashraf S, Zahid M, Hui H, Miall A, Kimpton S, Price MO, Price FW Jr, Gonzalez FJ, Rogan E, Jurkunas UV
Redox biology 2024 Feb;69:102986
Redox biology 2024 Feb;69:102986
Jujuboside A Attenuates Polycystic Ovary Syndrome Based on Estrogen Metabolism Through Activating AhR-mediated CYP1A2 Expression.
Zhou N, Lv W, Chen L, Chen K, He Q, Xie G, Ma J, Cao Y, Zhang B, Zhou X
Reproductive sciences (Thousand Oaks, Calif.) 2024 Aug;31(8):2234-2245
Reproductive sciences (Thousand Oaks, Calif.) 2024 Aug;31(8):2234-2245
Therapeutic effects of inĀ vivo administration of an inhibitor of tryptophan 2,3-dioxygenase (680c91) for the treatment of fibroids: a preclinical study.
Chuang TD, Ton N, Rysling S, Quintanilla D, Boos D, Khorram O
Fertility and sterility 2024 Apr;121(4):669-678
Fertility and sterility 2024 Apr;121(4):669-678
Qi Gong Wan ameliorates adipocyte hypertrophy and inflammation in adipose tissue in a PCOS mouse model through the Nrf2/HO-1/Cyp1b1 pathway: Integrating network pharmacology and experimental validation in vivo.
Zheng R, Shen H, Li J, Zhao J, Lu L, Hu M, Lin Z, Ma H, Tan H, Hu M, Li J
Journal of ethnopharmacology 2023 Jan 30;301:115824
Journal of ethnopharmacology 2023 Jan 30;301:115824
CYP1B1 promotes colorectal cancer liver metastasis by enhancing the growth of metastatic cancer cells via a fatty acids-dependent manner.
Jin L, Huang J, Guo L, Zhang B, Li Q, Li H, Yu M, Xie P, Yu Q, Chen Z, Liu S, Xu Y, Xiao Y, Lu M, Ye Q
Journal of gastrointestinal oncology 2023 Dec 31;14(6):2448-2465
Journal of gastrointestinal oncology 2023 Dec 31;14(6):2448-2465
Astilbin Activates the Reactive Oxidative Species/PPARĪ³ Pathway to Suppress Effector CD4(+) T Cell Activities via Direct Binding With Cytochrome P450 1B1.
Ding S, Lu G, Wang B, Xiang J, Hu C, Lin Z, Ding Y, Xiao W, Gong W
Frontiers in pharmacology 2022;13:848957
Frontiers in pharmacology 2022;13:848957
NUPR1 contributes to radiation resistance by maintaining ROS homeostasis via AhR/CYP signal axis in hepatocellular carcinoma.
Zhan Y, Zhang Z, Liu Y, Fang Y, Xie Y, Zheng Y, Li G, Liang L, Ding Y
BMC medicine 2022 Oct 19;20(1):365
BMC medicine 2022 Oct 19;20(1):365
CYP1B1: A Novel Molecular Biomarker Predicts Molecular Subtype, Tumor Microenvironment, and Immune Response in 33 Cancers.
Yuan B, Liu G, Dai Z, Wang L, Lin B, Zhang J
Cancers 2022 Nov 17;14(22)
Cancers 2022 Nov 17;14(22)
piRNA-14633 promotes cervical cancer cell malignancy in a METTL14-dependent m6A RNA methylation manner.
Xie Q, Li Z, Luo X, Wang D, Zhou Y, Zhao J, Gao S, Yang Y, Fu W, Kong L, Sun T
Journal of translational medicine 2022 Jan 29;20(1):51
Journal of translational medicine 2022 Jan 29;20(1):51
Reduced IRF4 expression promotes lytic phenotype in Type 2 EBV-infected B cells.
Bristol JA, Brand J, Ohashi M, Eichelberg MR, Casco A, Nelson SE, Hayes M, Romero-Masters JC, Baiu DC, Gumperz JE, Johannsen EC, Dinh HQ, Kenney SC
PLoS pathogens 2022 Apr;18(4):e1010453
PLoS pathogens 2022 Apr;18(4):e1010453
PET-CT and RNA sequencing reveal novel targets for acupuncture-induced lowering of blood pressure in spontaneously hypertensive rats.
Li J, Peng C, Lai D, Fang Y, Luo D, Zhou Z, Li C, Lai X
Scientific reports 2021 May 26;11(1):10973
Scientific reports 2021 May 26;11(1):10973
Sensing the Generation of Intracellular Free Electrons Using the Inactive Catalytic Subunit of Cytochrome P450s as a Sink.
Akintade DD, Chaudhuri B
Sensors (Basel, Switzerland) 2020 Jul 21;20(14)
Sensors (Basel, Switzerland) 2020 Jul 21;20(14)
Ocular Ciliopathies: Genetic and Mechanistic Insights into Developing Therapies.
Shivanna M, Anand M, Chakrabarti S, Khanna H
Current medicinal chemistry 2019;26(17):3120-3131
Current medicinal chemistry 2019;26(17):3120-3131
Role of the aryl hydrocarbon receptor signaling pathway in promoting mitochondrial biogenesis against oxidative damage in human melanocytes.
Wang X, Li S, Liu L, Jian Z, Cui T, Yang Y, Guo S, Yi X, Wang G, Li C, Gao T, Li K
Journal of dermatological science 2019 Oct;96(1):33-41
Journal of dermatological science 2019 Oct;96(1):33-41
CYP enzymes, expressed within live human suspension cells, are superior to widely-used microsomal enzymes in identifying potent CYP1A1/CYP1B1 inhibitors: Identification of quinazolinones as CYP1A1/CYP1B1 inhibitors that efficiently reverse B[a]P toxicity and cisplatin resistance.
Sonawane VR, Siddique MUM, Gatchie L, Williams IS, Bharate SB, Jayaprakash V, Sinha BN, Chaudhuri B
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2019 Apr 1;131:177-194
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2019 Apr 1;131:177-194
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- MCF-7 cells were subjected to SDS PAGE followed by western blot with 18505-1-AP( CYP1B1 Antibody) at dilution of 1:600
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CYP1B1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human CYP1B1. This antibody recognizes human,mouse,rat antigen. The CYP1B1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
