Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 11-1003 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-CYP1B1 Antibody
- Antibody type
- Polyclonal
- Description
- CYP1B1 (Cytochrome P450 1B1) belongs to the CYP450 superfamily of heme-binding mono-oxygenases which catalyze oxidation of various endogenous and exogenous substrates. The expression of Cyp1b1 plays an important role in the modulation of development and functions of the trabecular meshwork (TM). Mutations in Cyp1b1 found in patients with primary congenital glaucoma (PCG).It plays an important role in breast cancer development and progression by bioactivating endogenous estrogens and environmental carcinogens. It is over-expressed at the early stage of NNK-induced lung tumorigenesis.
- Reactivity
- Human
- Host
- Rabbit
- Antigen sequence
A partial length recombinant CYP1B1
protein (amino acids 1-260) was us
ed as the immunogen for this antibo
dy.- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
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Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Western blot analysis of CYP1B1. Anti-CYP1B1 antibody (11-1003) was used at 4 µg/ml on A549 lysate.