Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [22]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 55407-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#55407-1-AP, RRID:AB_11182836
- Product name
- KIF15 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated KIF15 antibody (Cat. #55407-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Map-1a regulates Sertoli cell BTB dynamics through the cytoskeletal organization of microtubule and F-actin.
The mitotic spindle-related seven-gene predicts the prognosis and immune microenvironment of lung adenocarcinoma.
Inducing Mitotic Catastrophe as a Therapeutic Approach to Improve Outcomes in Ewing Sarcoma.
Polyamine metabolism patterns characterized tumor microenvironment, prognosis, and response to immunotherapy in colorectal cancer.
Kif15 Is Required in the Development of Auditory System Using Zebrafish as a Model.
Transcriptional, Post-Transcriptional, and Post-Translational Mechanisms Rewrite the Tubulin Code During Cardiac Hypertrophy and Failure.
Rare and Common Variants in KIF15 Contribute to Genetic Risk of Idiopathic Pulmonary Fibrosis.
PSMD12 promotes the activation of the MEK-ERK pathway by upregulating KIF15 to promote the malignant progression of liver cancer.
KIF15 Promotes Progression of Castration Resistant Prostate Cancer by Activating EGFR Signaling Pathway.
KIF15 upregulation promotes leiomyosarcoma cell growth via promoting USP15-mediated DEK deubiquitylation.
Kinesin 12 (KIF15) contributes to the development and tumorigenicity of prostate cancer.
HIV-1 Establishes a Sanctuary Site in the Testis by Permeating the BTB Through Changes in Cytoskeletal Organization.
KIF15-Mediated Stabilization of AR and AR-V7 Contributes to Enzalutamide Resistance in Prostate Cancer.
KIF15 supports spermatogenesis via its effects on Sertoli cell microtubule, actin, vimentin, and septin cytoskeletons.
ZNF367-induced transcriptional activation of KIF15 accelerates the progression of breast cancer.
KIF15 contributes to cell proliferation and migration in breast cancer.
B7-H3 regulates KIF15-activated ERK1/2 pathway and contributes to radioresistance in colorectal cancer.
KIF11 and KIF15 mitotic kinesins are potential therapeutic vulnerabilities for malignant peripheral nerve sheath tumors.
KIF15 promotes bladder cancer proliferation via the MEK-ERK signaling pathway.
KIF15 plays a role in promoting the tumorigenicity of melanoma.
Increased KIF15 Expression Predicts a Poor Prognosis in Patients with Lung Adenocarcinoma.
Involvement of C-terminal truncation mutation of kinesin-5 in resistance to kinesin-5 inhibitor.
Wang L, Yan M, Bu T, Wu X, Li L, Silvestrini B, Sun F, Cheng CY, Chen H
Reproductive biology and endocrinology : RB&E 2024 Apr 3;22(1):36
Reproductive biology and endocrinology : RB&E 2024 Apr 3;22(1):36
The mitotic spindle-related seven-gene predicts the prognosis and immune microenvironment of lung adenocarcinoma.
Shen R, Li Z, Wu X
Journal of cancer research and clinical oncology 2023 Sep;149(12):10131-10141
Journal of cancer research and clinical oncology 2023 Sep;149(12):10131-10141
Inducing Mitotic Catastrophe as a Therapeutic Approach to Improve Outcomes in Ewing Sarcoma.
Turaga SM, Vishwakarma V, Hembruff SL, Gibbs BK, Sabu P, Puri RV, Pathak HB, Samuel G, Godwin AK
Cancers 2023 Oct 10;15(20)
Cancers 2023 Oct 10;15(20)
Polyamine metabolism patterns characterized tumor microenvironment, prognosis, and response to immunotherapy in colorectal cancer.
Zhang E, Ding C, Li S, Aikemu B, Zhou X, Fan X, Sun J, Yang X, Zheng M
Cancer cell international 2023 May 18;23(1):96
Cancer cell international 2023 May 18;23(1):96
Kif15 Is Required in the Development of Auditory System Using Zebrafish as a Model.
Zheng S, Tang D, Wang X, Liu C, Zuo N, Yan R, Wu C, Ma J, Wang C, Xu H, He Y, Liu D, Liu S
Frontiers in molecular neuroscience 2022;15:844568
Frontiers in molecular neuroscience 2022;15:844568
Transcriptional, Post-Transcriptional, and Post-Translational Mechanisms Rewrite the Tubulin Code During Cardiac Hypertrophy and Failure.
Phyo SA, Uchida K, Chen CY, Caporizzo MA, Bedi K, Griffin J, Margulies K, Prosser BL
Frontiers in cell and developmental biology 2022;10:837486
Frontiers in cell and developmental biology 2022;10:837486
Rare and Common Variants in KIF15 Contribute to Genetic Risk of Idiopathic Pulmonary Fibrosis.
Zhang D, Povysil G, Kobeissy PH, Li Q, Wang B, Amelotte M, Jaouadi H, Newton CA, Maher TM, Molyneaux PL, Noth I, Martinez FJ, Raghu G, Todd JL, Palmer SM, Haefliger C, Platt A, Petrovski S, Garcia JA, Goldstein DB, Garcia CK
American journal of respiratory and critical care medicine 2022 Jul 1;206(1):56-69
American journal of respiratory and critical care medicine 2022 Jul 1;206(1):56-69
PSMD12 promotes the activation of the MEK-ERK pathway by upregulating KIF15 to promote the malignant progression of liver cancer.
Zhang H, Li C, Liao S, Tu Y, Sun S, Yao F, Li Z, Wang Z
Cancer biology & therapy 2022 Dec 31;23(1):1-11
Cancer biology & therapy 2022 Dec 31;23(1):1-11
KIF15 Promotes Progression of Castration Resistant Prostate Cancer by Activating EGFR Signaling Pathway.
Gao L, Zhao R, Liu J, Zhang W, Sun F, Yin Q, Wang X, Wang M, Feng T, Qin Y, Cai W, Li Q, Dong H, Chen X, Xiong X, Liu H, Hu J, Chen W, Han B
Frontiers in oncology 2021;11:679173
Frontiers in oncology 2021;11:679173
KIF15 upregulation promotes leiomyosarcoma cell growth via promoting USP15-mediated DEK deubiquitylation.
Ge W, Chen Y, Guo Y, Zhao D, Mu L, Zhang K, Zhuo W
Biochemical and biophysical research communications 2021 Sep 17;570:117-124
Biochemical and biophysical research communications 2021 Sep 17;570:117-124
Kinesin 12 (KIF15) contributes to the development and tumorigenicity of prostate cancer.
Qureshi Z, Ahmad M, Yang WX, Tan FQ
Biochemical and biophysical research communications 2021 Oct 22;576:7-14
Biochemical and biophysical research communications 2021 Oct 22;576:7-14
HIV-1 Establishes a Sanctuary Site in the Testis by Permeating the BTB Through Changes in Cytoskeletal Organization.
Wu S, Frank I, Derby N, Martinelli E, Cheng CY
Endocrinology 2021 Nov 1;162(11)
Endocrinology 2021 Nov 1;162(11)
KIF15-Mediated Stabilization of AR and AR-V7 Contributes to Enzalutamide Resistance in Prostate Cancer.
Gao L, Zhang W, Zhang J, Liu J, Sun F, Liu H, Hu J, Wang X, Wang X, Su P, Chen S, Qu S, Shi B, Xiong X, Chen W, Dong X, Han B
Cancer research 2021 Feb 15;81(4):1026-1039
Cancer research 2021 Feb 15;81(4):1026-1039
KIF15 supports spermatogenesis via its effects on Sertoli cell microtubule, actin, vimentin, and septin cytoskeletons.
Wu S, Lv L, Li L, Wang L, Mao B, Li J, Shen X, Ge R, Wong CKC, Sun F, Cheng CY
Endocrinology 2021 Apr 1;162(4)
Endocrinology 2021 Apr 1;162(4)
ZNF367-induced transcriptional activation of KIF15 accelerates the progression of breast cancer.
Zeng H, Li T, Zhai D, Bi J, Kuang X, Lu S, Shan Z, Lin Y
International journal of biological sciences 2020;16(12):2084-2093
International journal of biological sciences 2020;16(12):2084-2093
KIF15 contributes to cell proliferation and migration in breast cancer.
Gao X, Zhu L, Lu X, Wang Y, Li R, Jiang G
Human cell 2020 Oct;33(4):1218-1228
Human cell 2020 Oct;33(4):1218-1228
B7-H3 regulates KIF15-activated ERK1/2 pathway and contributes to radioresistance in colorectal cancer.
Ma Y, Zhan S, Lu H, Wang R, Xu Y, Zhang G, Cao L, Shi T, Zhang X, Chen W
Cell death & disease 2020 Oct 3;11(10):824
Cell death & disease 2020 Oct 3;11(10):824
KIF11 and KIF15 mitotic kinesins are potential therapeutic vulnerabilities for malignant peripheral nerve sheath tumors.
Terribas E, Fernández M, Mazuelas H, Fernández-Rodríguez J, Biayna J, Blanco I, Bernal G, Ramos-Oliver I, Thomas C, Guha R, Zhang X, Gel B, Romagosa C, Ferrer M, Lázaro C, Serra E
Neuro-oncology advances 2020 Jul;2(Suppl 1):i62-i74
Neuro-oncology advances 2020 Jul;2(Suppl 1):i62-i74
KIF15 promotes bladder cancer proliferation via the MEK-ERK signaling pathway.
Zhao H, Bo Q, Wu Z, Liu Q, Li Y, Zhang N, Guo H, Shi B
Cancer management and research 2019;11:1857-1868
Cancer management and research 2019;11:1857-1868
KIF15 plays a role in promoting the tumorigenicity of melanoma.
Yu X, He X, Heindl LM, Song X, Fan J, Jia R
Experimental eye research 2019 Aug;185:107598
Experimental eye research 2019 Aug;185:107598
Increased KIF15 Expression Predicts a Poor Prognosis in Patients with Lung Adenocarcinoma.
Qiao Y, Chen J, Ma C, Liu Y, Li P, Wang Y, Hou L, Liu Z
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(1):1-10
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(1):1-10
Involvement of C-terminal truncation mutation of kinesin-5 in resistance to kinesin-5 inhibitor.
Saeki E, Yasuhira S, Shibazaki M, Tada H, Doita M, Masuda T, Maesawa C
PloS one 2018;13(12):e0209296
PloS one 2018;13(12):e0209296
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse thymus tissue were subjected to SDS PAGE followed by western blot with 55407-1-AP(KIF15 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 55407-1-AP(KIF15 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The KIF15 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human KIF15. This antibody recognizes human, mouse, rat antigen. The KIF15 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
