DCABH-1687

antibody from Creative Diagnostics

Targeting: RBX1 BA554C12.1, RNF75, ROC1

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

DCABH-1687

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DCABH-1687, RRID:AB_2475640

Product name

Rabbit Anti-Human RBX1 polyclonal antibody

Antibody type

Polyclonal

Description

ROC1 and ROC2 are the two highly conserved RING finger proteins that are homologous to APC11, a subunit of the anaphase-promoting complex (APC) . ROC1 and ROC2 commonly interact with all cullins while APC11 specifically interacts with APC2, a cullin-related APC subunit. ROC1 and APC11 immunocomplexes can catalyze isopeptide ligations to form polyubiquitin chains in an E1- and E2-dependent manner. ROC1 is thought to play a unique role in the ubiquitination reaction by heterodimerizing with cullin1 to catalyze ubiquitin polymerization.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Storage

2-8°C. Do not freeze. The user must validate any other storage conditions. When properly stored, the reagent is stable to the date indicated on the label. Do not use the reagent beyond the expiration date.