RA0728

antibody from Oursmab
Targeting: P2RY12 HORK3, P2Y12, SP1999
Provider product page for RA0728
Functional assay

Antibody data

Product number
RA0728 - Provider product page
Provider
Oursmab
Product name
Bentracimab (Biosimilar Reference Antibody) (Ticagrelor)
Antibody type
Monoclonal
Description
Bentracimab is an investigational, humanized monoclonal antibody fragment (Fab) designed as a specific reversal agent for the antiplatelet drug ticagrelor. It functions as a neutralizing antibody that binds with very high affinity to both ticagrelor and its active metabolite in the plasma, forming inactive complexes. This binding rapidly reverses the antiplatelet (P2Y12 receptor inhibitory) effects of ticagrelor, restoring platelet function. It is being developed for use in clinical scenarios where immediate reversal of ticagrelor's effects is required, such as in patients experiencing major bleeding or needing urgent surgery. It has demonstrated rapid and sustained reversal in Phase I and II trials.
Vial size
100 ¦Ìg,1 mg,5 mg-500,10 mg,25 mg,50 mg,174 mg
Concentration
Bottled at the concentration indicated on the vial.
Storage
store at -20¡ãC or -80¡ãC. Avoid repeated freeze.
P2RY12 protein structure - RA0728 shown in red.