PAK3

gene product
bPAK, hPAK3, MRX30, MRX47
PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. The protein encoded by this gene forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
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376 antibodies from 32 providers.

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AntibodyRefsTypeAVIWBELICCIPIHCFC
Abnova Corporation
5 antibodies
GeneTex
4 antibodies
LifeSpan BioSciences, Inc.
65 antibodies
Biorbyt
19 antibodies
Arigo
2 antibodies
Novus Biologicals
5 antibodies
Cell Signaling Technology, Inc
2 antibodies
antibodies-online
94 antibodies
NovoPro Bioscience Inc.
4 antibodies
Aviva Systems Biology
6 antibodies
OriGene
8 antibodies
Invitrogen Antibodies
6 antibodies
Acris Antibodies GmbH
8 antibodies
NSJ Bioreagents
3 antibodies
Abgent
6 antibodies
Atlas Antibodies
1 antibody
R&D Systems
1 antibody
Bioworld Technology, Inc
2 antibodies
ProSci
3 antibodies
RabMAbs
2 antibodies
United States Biological
94 antibodies
Creative Diagnostics
5 antibodies
EMD Millipore
2 antibodies
RayBiotech, Inc.
3 antibodies
Abbkine
2 antibodies
St John's Laboratory
2 antibodies
MyBioSource
4 antibodies
Abiocode, Inc.
1 antibody
Boster Biological Technology
1 antibody
Sigma-Aldrich
1 antibody
Abbexa
3 antibodies