11044-1-AP

antibody from Proteintech Group

Targeting: SRSF7 9G8, AAG3, HSSG1, RBM37, SFRS7, ZCCHC20, ZCRB2

Provider product page for 11044-1-AP

Western blot

ELISA

Immunocytochemistry

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [14]
Comments [0]
Validations
Immunocytochemistry [1]
Immunohistochemistry [1]

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Product number: 11044-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#11044-1-AP, RRID:AB_2185229
Product name: SFRS7 antibody
Antibody type: Polyclonal
Description: SFRS7 antibody (Cat. #11044-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB, ELISA.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

SRSF7 protein structure - 11044-1-AP shown in red.

Submitted references Targeting CLK1/SRSF7 axis-dependent alternative splicing sensitizes pancreatic ductal adenocarcinoma to chemotherapy and immunotherapy.

Zhang C, Chen Y, Zhu S, Wang Z, Lin H, Lu J, Zhang H, Weng Y, Huang X, Li G, Wu Y, Li Z, Hu J, Xie C, Lai J, Tian Y, Liao C, Chen S
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2025 Nov;83:101292

C9ORF72 poly-PR disrupts expression of ALS/FTD-implicated STMN2 through SRSF7.

Wang KS, Smeyers J, Eggan K, Budnik B, Mordes DA
Acta neuropathologica communications 2025 Mar 26;13(1):67

Discovery of Novel Oxazolo[4,3-f]purine Derivatives as Antitumor Agents through PPIA Interaction.

Li XJ, Zhang MC, Li X, Guan LL, Liang YR, Hao EJ, Wang Y, Guo HM
Journal of medicinal chemistry 2025 Mar 13;68(5):5573-5596

Host Factor SRSF7 Promotes HBV Replication Through Binding to and Stabilising Viral pgRNA.

Peng Y, Song Y, Liu X, Du X, Zhou Z, Yu G, Chen X, Lu F
Journal of viral hepatitis 2025 Jun;32(6):e70024

SRSF7 promotes pulmonary fibrosis through regulating PKM alternative splicing in lung fibroblasts.

Jin T, Gao H, Wang Y, Ning Z, Bing D, Wang Y, Chen Y, Tian X, Liu Q, Niu Z, Guo J, Sun J, Yang R, Wang Q, Li S, Li T, Zhou Y, He W, Lu Y, Gu Y, Liang H
Acta pharmaceutica Sinica. B 2025 Jun;15(6):3041-3058

Proteomic study identifies Aurora-A-mediated regulation of alternative splicing through multiple splicing factors.

Damodaran AP, Gavard O, Gagné JP, Rogalska ME, Behera AK, Mancini E, Bertolin G, Courtheoux T, Kumari B, Cailloce J, Mereau A, Poirier GG, Valcárcel J, Gonatopoulos-Pournatzis T, Watrin E, Prigent C
The Journal of biological chemistry 2025 Jan;301(1):108000

Host-specific SRSF7 regulates polymerase activity and replication of influenza A virus.

Zhao L, Li S, Deng L, Zhang Y, Jiang C, Wei Y, Xia J, Ping J
Microbes and infection 2024 Nov-Dec;26(8):105401

Serine/Arginine-Rich Splicing Factor 7 Knockdown Inhibits Aerobic Glycolysis and Growth in HepG2 Cells by Regulating PKM2 Expression.

Shi W, Yao X, Cao X, Fu Y, Wang Y
Current issues in molecular biology 2024 May 20;46(5):5023-5036

Proteomic Characterization Identifies Clinically Relevant Subgroups of Gastrointestinal Stromal Tumors.

Sun M, Tong Y, Yuan W, Wang Y, Pu Y, Huang W, Lv B, Xu C, Jiang W, Luo R, Fang R, Tang S, Ren L, Wang J, Feng J, Sun C, Shen K, He F, Hou Y, Ding C
Gastroenterology 2024 Mar;166(3):450-465.e33

SRSF7 is a promising prognostic biomarker in hepatocellular carcinoma and is associated with immune infiltration.

Shen W, Yuan L, Cheng F, Wu Z, Li X
Genes & genomics 2024 Jan;46(1):49-64

Specific Regulation of m(6)A by SRSF7 Promotes the Progression of Glioblastoma.

Cun Y, An S, Zheng H, Lan J, Chen W, Luo W, Yao C, Li X, Huang X, Sun X, Wu Z, Hu Y, Li Z, Zhang S, Wu G, Yang M, Tang M, Yu R, Liao X, Gao G, Zhao W, Wang J, Li J
Genomics, proteomics & bioinformatics 2023 Aug;21(4):707-728

Exonic splicing code and protein binding sites for calcium.

Pengelly RJ, Bakhtiar D, Borovská I, Královičová J, Vořechovský I
Nucleic acids research 2022 Jun 10;50(10):5493-5512

Sequence-dependent recruitment of SRSF1 and SRSF7 to intronless lncRNA NKILA promotes nuclear export via the TREX/TAP pathway.

Khan M, Hou S, Azam S, Lei H
Nucleic acids research 2021 Jun 21;49(11):6420-6436

C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles.

Lee KH, Zhang P, Kim HJ, Mitrea DM, Sarkar M, Freibaum BD, Cika J, Coughlin M, Messing J, Molliex A, Maxwell BA, Kim NC, Temirov J, Moore J, Kolaitis RM, Shaw TI, Bai B, Peng J, Kriwacki RW, Taylor JP
Cell 2016 Oct 20;167(3):774-788.e17

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunofluorescent analysis of HepG2 cells, using SFRS7 antibody 11044-1-AP at 1:100 dilution and FITC-labeled donkey anti-rabbit IgG(green). Blue pseudocolor = DAPI (fluorescent DNA dye).
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human prostate cancer using 11044-1-AP(SFRS7 antibody) at dilution of 1:50 (under 10x lens)
Sample type: tissue