13925-1-AP

antibody from Proteintech Group

Targeting: DCX DBCN, DC, LISX, SCLH, XLIS

Provider product page for 13925-1-AP

Western blot

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Immunocytochemistry

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [28]
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Validations
Western blot [1]
Immunohistochemistry [1]

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Product number: 13925-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#13925-1-AP, RRID:AB_2088476
Product name: DCX antibody
Antibody type: Polyclonal
Description: DCX antibody (Cat. #13925-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, ELISA.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

DCX protein structure - 13925-1-AP shown in red.

Submitted references Melatonin mitigates manganese-induced neural damage via modulation of gut microbiota-metabolism in mice.

He W, Wang X, Yang X, Zhang G, Zhang J, Chen L, Niu P, Chen T
The Science of the total environment 2024 May 1;923:171474

OXCT1 regulates hippocampal neurogenesis and alleviates cognitive impairment via the Akt/GSK-3β/β-catenin pathway after subarachnoid hemorrhage.

Qiu JY, Gao SQ, Chen YS, Wang X, Zhuang YS, Miao SH, Zheng XB, Zhao R, Sun Y, Zhou ML
Brain research 2024 Mar 15;1827:148758

Periplaneta Americana (L.) extract activates the ERK/CREB/BDNF pathway to promote post-stroke neuroregeneration and recovery of neurological functions in rats.

Rao J, Li H, Zhang H, Xiang X, Ding X, Li L, Geng F, Qi H
Journal of ethnopharmacology 2024 Mar 1;321:117400

Down-regulating nuclear factor of activated T cells 1 alleviates cognitive deficits in a mouse model of sepsis-associated encephalopathy, possibly by stimulating hippocampal neurogenesis.

Guo Y, Feng Y, Jiang F, Hu L, Shan T, Li H, Liao H, Bao H, Shi H, Si Y
Brain research 2024 Mar 1;1826:148731

Akkermansia muciniphila Is Beneficial to a Mouse Model of Parkinson's Disease, via Alleviated Neuroinflammation and Promoted Neurogenesis, with Involvement of SCFAs.

Qiao CM, Huang WY, Zhou Y, Quan W, Niu GY, Li T, Zhang MX, Wu J, Zhao LP, Zhao WJ, Cui C, Shen YQ
Brain sciences 2024 Feb 29;14(3)

A Gpr35-tuned gut microbe-brain metabolic axis regulates depressive-like behavior.

Cheng L, Wu H, Cai X, Zhang Y, Yu S, Hou Y, Yin Z, Yan Q, Wang Q, Sun T, Wang G, Yuan Y, Zhang X, Hao H, Zheng X
Cell host & microbe 2024 Feb 14;32(2):227-243.e6

miR-377-3p Regulates Hippocampal Neurogenesis via the Zfp462-Pbx1 Pathway and Mediates Anxiety-Like Behaviors in Prenatal Hypoxic Offspring.

Wang B, Zhu Y, Wei B, Zeng H, Zhang P, Li L, Wang H, Wu X, Zheng Y, Sun M
Molecular neurobiology 2024 Apr;61(4):1920-1935

Fecal Microbiota Transplantation from Aged Mice Render Recipient Mice Resistant to MPTP-Induced Nigrostriatal Degeneration Via a Neurogenesis-Dependent but Inflammation-Independent Manner.

Qiao CM, Zhou Y, Quan W, Ma XY, Zhao LP, Shi Y, Hong H, Wu J, Niu GY, Chen YN, Zhu S, Cui C, Zhao WJ, Shen YQ
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2023 Sep;20(5):1405-1426

Catalpol Alleviates Ischemic Stroke Through Promoting Angiogenesis and Facilitating Proliferation and Differentiation of Neural Stem Cells via the VEGF-A/KDR Pathway.

Sun S, Xu Y, Yu N, Zhang M, Wang J, Wan D, Tian Z, Zhu H
Molecular neurobiology 2023 Nov;60(11):6227-6247

20S-Protopanaxatriol improves cognitive function of Alzheimer's disease by promoting endogenous neurogenesis.

Zhang Q, Yang X, Liu J, Song J, Zhang S, Chen L, Zhang M
Food & function 2023 May 11;14(9):4191-4203

Adult Neurogenesis Is Altered by Circadian Phase Shifts and the Duper Mutation in Female Syrian Hamsters.

Bahiru MS, Bittman EL
eNeuro 2023 Mar;10(3)

Human cytomegalovirus pUL97 upregulates SOCS3 expression via transcription factor RFX7 in neural progenitor cells.

Wang XZ, Wen L, Zhou YP, Huang SN, Yang B, Cheng S, Zeng WB, Mei MJ, Sun JY, Jiang X, Cheng H, Luo MH
PLoS pathogens 2023 Feb;19(2):e1011166

Nose-to-brain translocation and nervous system injury in response to indium tin oxide nanoparticles of long-term low-dose exposures.

Pang Y, Qu J, Zhang H, Cao Y, Ma X, Wang S, Wang J, Wu J, Zhang T
The Science of the total environment 2023 Dec 20;905:167314

miR-146a-5p Modulates Adult Hippocampal Neurogenesis Deficits Through Klf4/p-Stat3 Signaling in APP/PS1 Mice.

Deng LJ, Wu D, Yang XF, Li T
Neuroscience 2023 Aug 21;526:314-325

Conditional deletion of MAD2B in forebrain neurons enhances hippocampus-dependent learning and memory in mice.

Cheng L, Su Y, Zhi K, Xie Y, Zhang C, Meng X
Frontiers in cellular neuroscience 2022;16:956029

A three-dimensional matrix system containing melatonin and neural stem cells repairs damage from traumatic brain injury in rats.

Fang XY, Zhao DW, Zhang C, Ge HF, Zhang XY, Zhao FC, Jiang YB, Feng H, Hu R
Neural regeneration research 2022 Nov;17(11):2512-2517

FOXG1 Contributes Adult Hippocampal Neurogenesis in Mice.

Wang J, Zhai HR, Ma SF, Shi HZ, Zhang WJ, Yun Q, Liu WJ, Liu ZZ, Zhang WN
International journal of molecular sciences 2022 Nov 29;23(23)

Bacteroides species differentially modulate depression-like behavior via gut-brain metabolic signaling.

Zhang Y, Fan Q, Hou Y, Zhang X, Yin Z, Cai X, Wei W, Wang J, He D, Wang G, Yuan Y, Hao H, Zheng X
Brain, behavior, and immunity 2022 May;102:11-22

Exercise-induced neuroprotection against cerebral ischemia/reperfusion injury is mediated via alleviating inflammasome-induced pyroptosis.

Liu MX, Luo L, Fu JH, He JY, Chen MY, He ZJ, Jia J
Experimental neurology 2022 Mar;349:113952

Nde1 is required for heterochromatin compaction and stability in neocortical neurons.

Chomiak AA, Guo Y, Kopsidas CA, McDaniel DP, Lowe CC, Pan H, Zhou X, Zhou Q, Doughty ML, Feng Y
iScience 2022 Jun 17;25(6):104354

Exosomes derived from bone-marrow mesenchymal stem cells alleviate cognitive decline in AD-like mice by improving BDNF-related neuropathology.

Liu S, Fan M, Xu JX, Yang LJ, Qi CC, Xia QR, Ge JF
Journal of neuroinflammation 2022 Feb 7;19(1):35

Ubiquitin-Specific Protease 22 Promotes Neural Stem Cells Stemness Maintenance and Adult Hippocampal Neurogenesis, Contributing to Cognitive Recovery Following Traumatic Brain Injury.

Zhang Z, Li J, Wang B, Hou C, Liu Q, Wang W, Zhao Y, Yin Q, Yang S, Zhang H, Yang X
Neuroscience 2022 Aug 1;496:219-229

Neuroprotection by cattle encephalon glycoside and ignotin beyond the time window of thrombolysis in ischemic stroke.

Zhong J, Li RW, Wang J, Wang Y, Ge HF, Xian JS, Feng H, Tan L
Neural regeneration research 2021 Feb;16(2):312-318

Ten-eleven translocation 1 mediated-DNA hydroxymethylation is required for myelination and remyelination in the mouse brain.

Zhang M, Wang J, Zhang K, Lu G, Liu Y, Ren K, Wang W, Xin D, Xu L, Mao H, Xing J, Gao X, Jin W, Berry K, Mikoshiba K, Wu S, Lu QR, Zhao X
Nature communications 2021 Aug 24;12(1):5091

Astragaloside IV improves neurobehavior and promotes hippocampal neurogenesis in MCAO rats though BDNF-TrkB signaling pathway.

Ni GX, Liang C, Wang J, Duan CQ, Wang P, Wang YL
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Oct;130:110353

Identification and immunohistochemical characterization of G-quadruplexes in mouse brain.

Asamitsu S, Imai Y, Yabuki Y, Ikenoshita S, Takeuchi M, Kashiwagi H, Tanoue Y, Fukuda T, Shioda N
Biochemical and biophysical research communications 2020 Oct 8;531(1):67-74

G protein-coupled estrogen receptor 1 negatively regulates the proliferation of mouse-derived neural stem/progenitor cells via extracellular signal-regulated kinase pathway.

Zhong J, Ge HF, Zhang C, Chen JY, Li HH, Fang XY, Tan L, Liu X, Jia ZC, Feng H, Hu R
Brain research 2019 Jul 1;1714:158-165

HDAC1 Silence Promotes Neuroprotective Effects of Human Umbilical Cord-Derived Mesenchymal Stem Cells in a Mouse Model of Traumatic Brain Injury via PI3K/AKT Pathway.

Xu L, Xing Q, Huang T, Zhou J, Liu T, Cui Y, Cheng T, Wang Y, Zhou X, Yang B, Yang GL, Zhang J, Zang X, Ma S, Guan F
Frontiers in cellular neuroscience 2018;12:498

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: human brain tissue were subjected to SDS PAGE followed by western blot with 13925-1-AP(DCX antibody) at dilution of 1:600
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The DCX antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human DCX. This antibody recognizes human,mouse,rat antigen. The DCX antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Appendix: 13925-1-AP.pdf

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