Antibody data
- Antibody Data
- Antigen structure
- References [63]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
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- Product number
- 13925-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13925-1-AP, RRID:AB_2088476
- Product name
- DCX antibody
- Antibody type
- Polyclonal
- Description
- DCX antibody (Cat. #13925-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Neural stem cell transplantation attenuates cognitive decline and neuroinflammation in a mouse model of Alzheimer's disease with chronic cerebral hypoperfusion.
Brain-Targeted RVG-Liposomal Melatonin Ameliorates Manganese Neurotoxicity by Enhancing Neurogenesis and Modulating Systemic Amino Acid Profiles.
Taurocholic Acid Is Associated With Disturbed Functional Connectivity in the Hippocampus of Patients With Depression.
GR/HDAC3 Regulates Npas4 Signaling Pathway and Mediates Cognitive Impairment in Prenatal Hypoxia Male Offspring.
Pseudohypoxia induced by iron chelators preserves working memory performance in aged mice.
Nrf2 overexpression reprograms neural stem cell fate: promoting neuronal differentiation and functional recovery post-ischemic stroke via suppression of the ROS/NF-κB axis.
Aerobic Exercise Promotes Hippocampal Neurogenesis and Ameliorates Cognitive Dysfunction Induced by Unilateral Labyrinthectomy.
Protective Effects of Crocin Against Fluoride-Induced Neurotoxicity: Involvement of Wnt10b/β-Catenin Signaling.
Microalgae-MOF integrated drug delivery system for cranial radiotherapy and chemotherapy-induced brain injury.
Neuroprotective effects of quercetin in LPS-induced depression: implications for antidepressant therapy.
PGC-1α promotes the survival of newborn neurons within AD hippocampus through activation of the FNDC5/BDNF/TrkB signaling pathway.
Experimental validation, molecular docking, proteomic analysis and network pharmacology reveal Morroniside promoting neurogenesis and improving cognitive impairment via Notch1/Hes1 pathway in intracerebroventricular-streptozotocin mice.
PGC-1α Expands Neural Precursor Pool and Facilitates Cognitive Recovery Within AD Hippocampus Through the Regulation of Mitochondrial Dynamics.
Tailoring the therapeutic potential of stem cell spheroid-derived decellularized ECM through post-decellularization BDNF incorporation to enhance brain repair.
Deficiency of nNOS in adult-born dentate granule cells causes epilepsy.
Aerobic Exercise Training Exerts Neuroprotective Effects in Alzheimer's Disease Mice by Regulating Endoplasmic Reticulum Stress-Autophagy Pathway-Mediated Pyroptosis.
Indoleamine 2, 3-dioxygenase 1 inhibition mediates the therapeutic effects in Parkinson's disease mice by modulating inflammation and neurogenesis in a gut microbiota dependent manner.
Indole-3-Propionic Acid Attenuates Neuroinflammation and Cognitive Deficits by Inhibiting the RAGE-JAK2-STAT3 Signaling Pathway.
Aberrant Development of Hippocampal GABAergic Neurons Arising from Hypothyroidism Contributes to Memory Deficits in Mice Through Maf Suppressing Mef2c.
Mechanism of S100A9-mediated astrocyte activation via TLR4/NF-κB in Parkinson's disease.
1-methyl-tryptophan improves anxiety-like behavior in colitis mice by inhibiting neuroinflammation, promoting cell regeneration, and decreasing apoptosis.
Mechanism of Buyang Huanwu Decoction mediating Cav1-regulated Wnt pathway to promote neural regeneration in cerebral ischemic mice.
Suppressing DUSP16 overexpression induced by ELK1 promotes neural progenitor cell differentiation in mouse models of Alzheimer's disease.
Sex-dimorphic reprogramming of fetal mouse brain development by maternal estradiol excess.
Correction of dysregulated lipid metabolism normalizes gene expression in oligodendrocytes and prolongs lifespan in female poly-GA C9orf72 mice.
Jujuboside A Regulates Calcium Homeostasis and Structural Plasticity to Alleviate Depression-Like Behavior via Shh Signaling in Immature Neurons.
Enriched environment treatment promotes neurofunctional recovery by regulating the ALK5/Smad2/3/Gadd45β signaling pathway in rats with cerebral ischemia /reperfusion injury.
Electroacupuncture attenuates depressive-like behaviors in poststroke depression mice through promoting hippocampal neurogenesis and inhibiting TLR4/NF-κB/NLRP3 signaling pathway.
Dexmedetomidine Attenuates Neuroinflammation-Mediated Hippocampal Neurogenesis Impairment in Sepsis-Associated Encephalopathy Mice through Central α2A-Adrenoceptor.
The Accessory Olfactory Bulb in Arvicola scherman: A Neuroanatomical Study in a Subterranean Mammal.
Melatonin mitigates manganese-induced neural damage via modulation of gut microbiota-metabolism in mice.
OXCT1 regulates hippocampal neurogenesis and alleviates cognitive impairment via the Akt/GSK-3β/β-catenin pathway after subarachnoid hemorrhage.
Periplaneta Americana (L.) extract activates the ERK/CREB/BDNF pathway to promote post-stroke neuroregeneration and recovery of neurological functions in rats.
Down-regulating nuclear factor of activated T cells 1 alleviates cognitive deficits in a mouse model of sepsis-associated encephalopathy, possibly by stimulating hippocampal neurogenesis.
m6a methylation orchestrates IMP1 regulation of microtubules during human neuronal differentiation.
Local Delivery of Dual Stem Cell-Derived Exosomes Using an Electrospun Nanofibrous Platform for the Treatment of Traumatic Brain Injury.
Akkermansia muciniphila Is Beneficial to a Mouse Model of Parkinson's Disease, via Alleviated Neuroinflammation and Promoted Neurogenesis, with Involvement of SCFAs.
A Gpr35-tuned gut microbe-brain metabolic axis regulates depressive-like behavior.
GR/P300 Regulates MKP1 Signaling Pathway and Mediates Depression-like Behavior in Prenatally Stressed Offspring.
Ginsenoside Rg1 enriches gut microbial indole-3-acetic acid to alleviate depression-like behavior in mice via oxytocin signaling.
Curcumin activates the Wnt/β-catenin signaling pathway to alleviate hippocampal neurogenesis abnormalities caused by intermittent hypoxia: A study based on network pharmacology and experimental verification.
miR-377-3p Regulates Hippocampal Neurogenesis via the Zfp462-Pbx1 Pathway and Mediates Anxiety-Like Behaviors in Prenatal Hypoxic Offspring.
Fecal Microbiota Transplantation from Aged Mice Render Recipient Mice Resistant to MPTP-Induced Nigrostriatal Degeneration Via a Neurogenesis-Dependent but Inflammation-Independent Manner.
Catalpol Alleviates Ischemic Stroke Through Promoting Angiogenesis and Facilitating Proliferation and Differentiation of Neural Stem Cells via the VEGF-A/KDR Pathway.
20S-Protopanaxatriol improves cognitive function of Alzheimer's disease by promoting endogenous neurogenesis.
Adult Neurogenesis Is Altered by Circadian Phase Shifts and the Duper Mutation in Female Syrian Hamsters.
Human cytomegalovirus pUL97 upregulates SOCS3 expression via transcription factor RFX7 in neural progenitor cells.
Nose-to-brain translocation and nervous system injury in response to indium tin oxide nanoparticles of long-term low-dose exposures.
miR-146a-5p Modulates Adult Hippocampal Neurogenesis Deficits Through Klf4/p-Stat3 Signaling in APP/PS1 Mice.
Conditional deletion of MAD2B in forebrain neurons enhances hippocampus-dependent learning and memory in mice.
A three-dimensional matrix system containing melatonin and neural stem cells repairs damage from traumatic brain injury in rats.
FOXG1 Contributes Adult Hippocampal Neurogenesis in Mice.
Bacteroides species differentially modulate depression-like behavior via gut-brain metabolic signaling.
Exercise-induced neuroprotection against cerebral ischemia/reperfusion injury is mediated via alleviating inflammasome-induced pyroptosis.
Nde1 is required for heterochromatin compaction and stability in neocortical neurons.
Exosomes derived from bone-marrow mesenchymal stem cells alleviate cognitive decline in AD-like mice by improving BDNF-related neuropathology.
Ubiquitin-Specific Protease 22 Promotes Neural Stem Cells Stemness Maintenance and Adult Hippocampal Neurogenesis, Contributing to Cognitive Recovery Following Traumatic Brain Injury.
Neuroprotection by cattle encephalon glycoside and ignotin beyond the time window of thrombolysis in ischemic stroke.
Ten-eleven translocation 1 mediated-DNA hydroxymethylation is required for myelination and remyelination in the mouse brain.
Astragaloside IV improves neurobehavior and promotes hippocampal neurogenesis in MCAO rats though BDNF-TrkB signaling pathway.
Identification and immunohistochemical characterization of G-quadruplexes in mouse brain.
G protein-coupled estrogen receptor 1 negatively regulates the proliferation of mouse-derived neural stem/progenitor cells via extracellular signal-regulated kinase pathway.
HDAC1 Silence Promotes Neuroprotective Effects of Human Umbilical Cord-Derived Mesenchymal Stem Cells in a Mouse Model of Traumatic Brain Injury via PI3K/AKT Pathway.
Lu Z, Zhou H, Tang H, Luo S, Wang J, Zheng X, Hu Y, Qin Q, Yang C, Mo S, Huang X, Tang L, Huang B, Xu W, Nong J, Gan G, Qin D, Peng Z, Jian C, Liu X, Li X, Shang J
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Brain-Targeted RVG-Liposomal Melatonin Ameliorates Manganese Neurotoxicity by Enhancing Neurogenesis and Modulating Systemic Amino Acid Profiles.
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Taurocholic Acid Is Associated With Disturbed Functional Connectivity in the Hippocampus of Patients With Depression.
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GR/HDAC3 Regulates Npas4 Signaling Pathway and Mediates Cognitive Impairment in Prenatal Hypoxia Male Offspring.
Zhao Z, Song Y, Yu X, Gao Q, Wang B, Sun M
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Pseudohypoxia induced by iron chelators preserves working memory performance in aged mice.
Ohara T, Iwasaki Y, Kasai T, Yamashita T, Komaki S, Hamada Y, Fujisawa M, Matsukawa A
Scientific reports 2026 Mar 2;16(1)
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Nrf2 overexpression reprograms neural stem cell fate: promoting neuronal differentiation and functional recovery post-ischemic stroke via suppression of the ROS/NF-κB axis.
Hao P, Liu S, Wang Y, Xu J, Ma R, Mai D, Chen R, Tang S, Huo S, Li R, Gao J, Xiao Y, Du X, Ji Q, Zhu W, Liu H, Wang B
Journal of translational medicine 2026 Jan 14;24(1):169
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Aerobic Exercise Promotes Hippocampal Neurogenesis and Ameliorates Cognitive Dysfunction Induced by Unilateral Labyrinthectomy.
Zhou Z, Yu X, Tian E, Guo Z, Chen J, Guo J, Shi S, Xu W, Zhai N, Qiao C, Zhang Y, Wang J, Lu Y, Zhang S
CNS neuroscience & therapeutics 2026 Feb;32(2):e70773
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Protective Effects of Crocin Against Fluoride-Induced Neurotoxicity: Involvement of Wnt10b/β-Catenin Signaling.
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Biological trace element research 2026 Feb 11;
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Microalgae-MOF integrated drug delivery system for cranial radiotherapy and chemotherapy-induced brain injury.
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Neuroprotective effects of quercetin in LPS-induced depression: implications for antidepressant therapy.
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Deficiency of nNOS in adult-born dentate granule cells causes epilepsy.
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CNS neuroscience & therapeutics 2025 Nov;31(11):e70620
Indoleamine 2, 3-dioxygenase 1 inhibition mediates the therapeutic effects in Parkinson's disease mice by modulating inflammation and neurogenesis in a gut microbiota dependent manner.
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Indole-3-Propionic Acid Attenuates Neuroinflammation and Cognitive Deficits by Inhibiting the RAGE-JAK2-STAT3 Signaling Pathway.
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1-methyl-tryptophan improves anxiety-like behavior in colitis mice by inhibiting neuroinflammation, promoting cell regeneration, and decreasing apoptosis.
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Electroacupuncture attenuates depressive-like behaviors in poststroke depression mice through promoting hippocampal neurogenesis and inhibiting TLR4/NF-κB/NLRP3 signaling pathway.
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Down-regulating nuclear factor of activated T cells 1 alleviates cognitive deficits in a mouse model of sepsis-associated encephalopathy, possibly by stimulating hippocampal neurogenesis.
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Brain sciences 2024 Feb 29;14(3)
A Gpr35-tuned gut microbe-brain metabolic axis regulates depressive-like behavior.
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GR/P300 Regulates MKP1 Signaling Pathway and Mediates Depression-like Behavior in Prenatally Stressed Offspring.
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International immunopharmacology 2024 Dec 25;143(Pt 1):113299
miR-377-3p Regulates Hippocampal Neurogenesis via the Zfp462-Pbx1 Pathway and Mediates Anxiety-Like Behaviors in Prenatal Hypoxic Offspring.
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Molecular neurobiology 2024 Apr;61(4):1920-1935
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Molecular neurobiology 2023 Nov;60(11):6227-6247
20S-Protopanaxatriol improves cognitive function of Alzheimer's disease by promoting endogenous neurogenesis.
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Food & function 2023 May 11;14(9):4191-4203
Adult Neurogenesis Is Altered by Circadian Phase Shifts and the Duper Mutation in Female Syrian Hamsters.
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eNeuro 2023 Mar;10(3)
Human cytomegalovirus pUL97 upregulates SOCS3 expression via transcription factor RFX7 in neural progenitor cells.
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PLoS pathogens 2023 Feb;19(2):e1011166
PLoS pathogens 2023 Feb;19(2):e1011166
Nose-to-brain translocation and nervous system injury in response to indium tin oxide nanoparticles of long-term low-dose exposures.
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The Science of the total environment 2023 Dec 20;905:167314
The Science of the total environment 2023 Dec 20;905:167314
miR-146a-5p Modulates Adult Hippocampal Neurogenesis Deficits Through Klf4/p-Stat3 Signaling in APP/PS1 Mice.
Deng LJ, Wu D, Yang XF, Li T
Neuroscience 2023 Aug 21;526:314-325
Neuroscience 2023 Aug 21;526:314-325
Conditional deletion of MAD2B in forebrain neurons enhances hippocampus-dependent learning and memory in mice.
Cheng L, Su Y, Zhi K, Xie Y, Zhang C, Meng X
Frontiers in cellular neuroscience 2022;16:956029
Frontiers in cellular neuroscience 2022;16:956029
A three-dimensional matrix system containing melatonin and neural stem cells repairs damage from traumatic brain injury in rats.
Fang XY, Zhao DW, Zhang C, Ge HF, Zhang XY, Zhao FC, Jiang YB, Feng H, Hu R
Neural regeneration research 2022 Nov;17(11):2512-2517
Neural regeneration research 2022 Nov;17(11):2512-2517
FOXG1 Contributes Adult Hippocampal Neurogenesis in Mice.
Wang J, Zhai HR, Ma SF, Shi HZ, Zhang WJ, Yun Q, Liu WJ, Liu ZZ, Zhang WN
International journal of molecular sciences 2022 Nov 29;23(23)
International journal of molecular sciences 2022 Nov 29;23(23)
Bacteroides species differentially modulate depression-like behavior via gut-brain metabolic signaling.
Zhang Y, Fan Q, Hou Y, Zhang X, Yin Z, Cai X, Wei W, Wang J, He D, Wang G, Yuan Y, Hao H, Zheng X
Brain, behavior, and immunity 2022 May;102:11-22
Brain, behavior, and immunity 2022 May;102:11-22
Exercise-induced neuroprotection against cerebral ischemia/reperfusion injury is mediated via alleviating inflammasome-induced pyroptosis.
Liu MX, Luo L, Fu JH, He JY, Chen MY, He ZJ, Jia J
Experimental neurology 2022 Mar;349:113952
Experimental neurology 2022 Mar;349:113952
Nde1 is required for heterochromatin compaction and stability in neocortical neurons.
Chomiak AA, Guo Y, Kopsidas CA, McDaniel DP, Lowe CC, Pan H, Zhou X, Zhou Q, Doughty ML, Feng Y
iScience 2022 Jun 17;25(6):104354
iScience 2022 Jun 17;25(6):104354
Exosomes derived from bone-marrow mesenchymal stem cells alleviate cognitive decline in AD-like mice by improving BDNF-related neuropathology.
Liu S, Fan M, Xu JX, Yang LJ, Qi CC, Xia QR, Ge JF
Journal of neuroinflammation 2022 Feb 7;19(1):35
Journal of neuroinflammation 2022 Feb 7;19(1):35
Ubiquitin-Specific Protease 22 Promotes Neural Stem Cells Stemness Maintenance and Adult Hippocampal Neurogenesis, Contributing to Cognitive Recovery Following Traumatic Brain Injury.
Zhang Z, Li J, Wang B, Hou C, Liu Q, Wang W, Zhao Y, Yin Q, Yang S, Zhang H, Yang X
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Neuroscience 2022 Aug 1;496:219-229
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Frontiers in cellular neuroscience 2018;12:498
Frontiers in cellular neuroscience 2018;12:498
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 13925-1-AP(DCX antibody) at dilution of 1:600
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The DCX antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human DCX. This antibody recognizes human,mouse,rat antigen. The DCX antibody has been validated for the following applications: ELISA, WB, IHC analysis.