66970-1-Ig

antibody from Proteintech Group

Targeting: NPHS1 CNF, NPHN

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

66970-1-Ig

Provider

Proteintech Group

Product name

Nephrin antibody

Antibody type

Monoclonal

Description

Nephrin antibody (Cat. #66970-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human and has been validated for the following applications: IHC,ELISA.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

1D11H8

Vial size

20ul, 150ul

References

Submitted references

Advancing the clinical assessment of glomerular podocyte pathology in kidney biopsies via super-resolution microscopy and angiopoietin-like 4 staining.

Liu X, Wang S, Liu G, Wang Y, Shang S, Zou G, Jiang S, Wang X, Yang L, Li W
Theranostics 2025;15(3):784-803

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Anti-nephrin antibody: a potential biomarker of minimal change disease.

Chen Q, Chen S, Ye Q, Lin W, Liao Y, Xiong Y, Xu J, Gao R, Li B, Liu L, Wei L
Clinical kidney journal 2025 Mar;18(3):sfaf012

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Single-cell analysis of diquat-induced oxidative stress and its impact on organ-specific toxicity.

Chen Z, Lin G, Ye K, Wang J, Tang M, Lai K, Yuan Y, Lin S, Dai X, Chen H, Ma H, Zhou J, Xu Y
Ecotoxicology and environmental safety 2025 Jun 1;297:118246

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The compound XueShuanTong promotes podocyte mitochondrial autophagy via the AMPK/mTOR pathway to alleviate diabetic nephropathy injury.

Zhang C, Ren W, Lu X, Feng L, Li J, Zhu B
Mitochondrion 2025 Jul;83:102024

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Effectiveness of a Novel PLA2R1 Knock-In Rat Model in Repairing Renal Function Damage.

Huang B, Sui WD, Zhang ZT, Zhao L, Li YY, Yang DH, Zhou Y
Journal of biochemical and molecular toxicology 2025 Jan;39(1):e70056

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EIF4A3-induced circFAT1 promotes high glucose-induced podocyte damage via miR-30e-5p/SOX4 axis.

Huang Y, Liu Y, Yang M, Zhao L, Chen M
RNA biology 2025 Dec;22(1):1-13

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Lactate drives epithelial-mesenchymal transition in diabetic kidney disease via the H3K14la/KLF5 pathway.

Zhang X, Chen J, Lin R, Huang Y, Wang Z, Xu S, Wang L, Chen F, Zhang J, Pan K, Yin Z
Redox biology 2024 Sep;75:103246

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Effectiveness of a novel rat model of off-target PLA2R1 knockout to renal impairment.

Huang B, Zhang Z, Sui W, Zhao L, Li Y, Feng L, Yang D, Zhou Y
Genomics 2024 Mar;116(2):110796

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QiDiTangShen granules alleviates diabetic nephropathy podocyte injury: A network pharmacology study and experimental validation in vivo and vitro.

Gao F, Zhou Y, Yu B, Xie H, Shi Y, Zhang X, Liu H
Heliyon 2024 Jan 15;10(1):e23535

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Effectiveness of a Novel PLA2R1 Knock-in Middle Age Rat Model in Repairing Renal Function Damage.

Yang D, Zhang Z, Zhao L, Sui W, Li Y, Zhou Y, Huang B
Cell biochemistry and function 2024 Dec;42(8):e70032

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The inhibition of rutin on Src kinase blocks high glucose-induced EGFR/ERK transactivation in diabetic nephropathy by integrative approach of network pharmacology and experimental verification.

Wu L, Li L, Wang X, Wu H, Li M, Wang Y, Sheng P, An X, Yan M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156220

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Astragaloside IV attenuates podocyte apoptosis via regulating TXNIP/NLRP3/GSDMD signaling pathway in diabetic nephropathy.

Hu Z, Zhou Y, Gao C, Liu J, Pan C, Guo J
Diabetology & metabolic syndrome 2024 Dec 18;16(1):296

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Deciphering the pharmacological mechanisms of Rostellularia procumbens (L) Nees. Extract alleviates adriamycin-induced nephropathy in vivo and in vitro.

Ai Z, Wang M, Zhou Y, Yuan D, Jian Q, Wu S, Liu B, Yang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 May;113:154736

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Wen-Shen-Jian-Pi-Hua-Tan decoction protects against early obesity-related glomerulopathy by improving renal bile acid composition and suppressing lipogenesis, inflammation, and fibrosis.

Song D, Zhang A, Hu X, Zeng M, Zhou H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154861

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Urinary exosomes from patients with diabetic kidney disease induced podocyte apoptosis via microRNA-145-5p/Srgap2 and the RhoA/ROCK pathway.

Han L, Wang S, Li J, Zhao L, Zhou H
Experimental and molecular pathology 2023 Dec;134:104877

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Non-canonical Wnt/calcium signaling is protective against podocyte injury and glomerulosclerosis.

Zhou D, Wang Y, Gui Y, Fu H, Zhou S, Wang Y, Bastacky SI, Stolz DB, Liu Y
Kidney international 2022 Jul;102(1):96-107

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Experimental study on renoprotective effect of intermedin on diabetic nephropathy.

Wang Y, Tian J, Mi Y, Ren X, Lian S, Kang J, Wang J, Zang H, Wu Z, Yang J, Qiao X, Zhou X, Wang G, Zhou Y, Li R
Molecular and cellular endocrinology 2021 May 15;528:111224

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Tetrandrine Suppresses Transient Receptor Potential Cation Channel Protein 6 Overexpression- Induced Podocyte Damage via Blockage of RhoA/ROCK1 Signaling.

Yu J, Zhu C, Yin J, Yu D, Wan F, Tang X, Jiang X
Drug design, development and therapy 2020;14:361-370