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- References [11]
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- Product number
- 17097-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17097-1-AP, RRID:AB_2132807
- Product name
- LARS2 antibody
- Antibody type
- Polyclonal
- Description
- LARS2 antibody (Cat. #17097-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Tracing the origin of alveolar stem cells in lung repair and regeneration.
Single-cell transcriptomic profiling reveals decreased ER protein Reticulon3 drives the progression of renal fibrosis.
Decreased expression of mitochondrial aminoacyl-tRNA synthetases causes downregulation of OXPHOS subunits in type 2 diabetic muscle.
LARS2 Regulates Apoptosis via ROS-Mediated Mitochondrial Dysfunction and Endoplasmic Reticulum Stress in Ovarian Granulosa Cells.
RNA granule-clustered mitochondrial aminoacyl-tRNA synthetases form multiple complexes with the potential to fine-tune tRNA aminoacylation.
Single-Cell Transcriptional Profiling Reveals Sex and Age Diversity of Gene Expression in Mouse Endothelial Cells.
Mitochondrial Threonyl-tRNA Synthetase TARS2 Is Required for Threonine-Sensitive mTORC1 Activation.
Single-Cell RNA Sequencing Unveils Unique Transcriptomic Signatures of Organ-Specific Endothelial Cells.
Overexpression of mitochondrial histidyl-tRNA synthetase restores mitochondrial dysfunction caused by a deafness-associated tRNA(His) mutation.
Deletion of Mtu1 (Trmu) in zebrafish revealed the essential role of tRNA modification in mitochondrial biogenesis and hearing function.
The isolated carboxy-terminal domain of human mitochondrial leucyl-tRNA synthetase rescues the pathological phenotype of mitochondrial tRNA mutations in human cells.
Liu K, Meng X, Liu Z, Tang M, Lv Z, Huang X, Jin H, Han X, Liu X, Pu W, Zhu H, Zhou B
Cell 2024 May 9;187(10):2428-2445.e20
Cell 2024 May 9;187(10):2428-2445.e20
Single-cell transcriptomic profiling reveals decreased ER protein Reticulon3 drives the progression of renal fibrosis.
Guo S, Dong Y, Du R, Liu YX, Liu S, Wang Q, Liu JS, Xu H, Jiang YJ, Hao H, Fan LL, Xiang R
Molecular biomedicine 2024 Jun 28;5(1):24
Molecular biomedicine 2024 Jun 28;5(1):24
Decreased expression of mitochondrial aminoacyl-tRNA synthetases causes downregulation of OXPHOS subunits in type 2 diabetic muscle.
López-Soldado I, Torres AG, Ventura R, Martínez-Ruiz I, Díaz-Ramos A, Planet E, Cooper D, Pazderska A, Wanic K, O'Hanlon D, O'Gorman DJ, Carbonell T, Ribas de Pouplana L, Nolan JJ, Zorzano A, Hernández-Alvarez MI
Redox biology 2023 May;61:102630
Redox biology 2023 May;61:102630
LARS2 Regulates Apoptosis via ROS-Mediated Mitochondrial Dysfunction and Endoplasmic Reticulum Stress in Ovarian Granulosa Cells.
Feng S, Wan S, Liu S, Wang W, Tang M, Bai L, Zhu Y
Oxidative medicine and cellular longevity 2022;2022:5501346
Oxidative medicine and cellular longevity 2022;2022:5501346
RNA granule-clustered mitochondrial aminoacyl-tRNA synthetases form multiple complexes with the potential to fine-tune tRNA aminoacylation.
Peng GX, Mao XL, Cao Y, Yao SY, Li QR, Chen X, Wang ED, Zhou XL
Nucleic acids research 2022 Dec 9;50(22):12951-12968
Nucleic acids research 2022 Dec 9;50(22):12951-12968
Single-Cell Transcriptional Profiling Reveals Sex and Age Diversity of Gene Expression in Mouse Endothelial Cells.
Huang X, Shen W, Veizades S, Liang G, Sayed N, Nguyen PK
Frontiers in genetics 2021;12:590377
Frontiers in genetics 2021;12:590377
Mitochondrial Threonyl-tRNA Synthetase TARS2 Is Required for Threonine-Sensitive mTORC1 Activation.
Kim SH, Choi JH, Wang P, Go CD, Hesketh GG, Gingras AC, Jafarnejad SM, Sonenberg N
Molecular cell 2021 Jan 21;81(2):398-407.e4
Molecular cell 2021 Jan 21;81(2):398-407.e4
Single-Cell RNA Sequencing Unveils Unique Transcriptomic Signatures of Organ-Specific Endothelial Cells.
Paik DT, Tian L, Williams IM, Rhee S, Zhang H, Liu C, Mishra R, Wu SM, Red-Horse K, Wu JC
Circulation 2020 Nov 10;142(19):1848-1862
Circulation 2020 Nov 10;142(19):1848-1862
Overexpression of mitochondrial histidyl-tRNA synthetase restores mitochondrial dysfunction caused by a deafness-associated tRNA(His) mutation.
Gong S, Wang X, Meng F, Cui L, Yi Q, Zhao Q, Cang X, Cai Z, Mo JQ, Liang Y, Guan MX
The Journal of biological chemistry 2020 Jan 24;295(4):940-954
The Journal of biological chemistry 2020 Jan 24;295(4):940-954
Deletion of Mtu1 (Trmu) in zebrafish revealed the essential role of tRNA modification in mitochondrial biogenesis and hearing function.
Zhang Q, Zhang L, Chen D, He X, Yao S, Zhang Z, Chen Y, Guan MX
Nucleic acids research 2018 Nov 16;46(20):10930-10945
Nucleic acids research 2018 Nov 16;46(20):10930-10945
The isolated carboxy-terminal domain of human mitochondrial leucyl-tRNA synthetase rescues the pathological phenotype of mitochondrial tRNA mutations in human cells.
Perli E, Giordano C, Pisano A, Montanari A, Campese AF, Reyes A, Ghezzi D, Nasca A, Tuppen HA, Orlandi M, Di Micco P, Poser E, Taylor RW, Colotti G, Francisci S, Morea V, Frontali L, Zeviani M, d'Amati G
EMBO molecular medicine 2014 Feb;6(2):169-82
EMBO molecular medicine 2014 Feb;6(2):169-82
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The LARS2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human LARS2. This antibody recognizes human,mouse,rat antigen. The LARS2 antibody has been validated for the following applications: ELISA, WB analysis.
