372603

antibody from BioLegend

Targeting: XCR1 CCXCR1, GPR5

Flow cytometry (Supportive data in Antibodypedia)

Antibody Data

Product number

372603

Provider

BioLegend

Proper citation

BioLegend Cat#372603, RRID:AB_2632710

Product name

PE anti-human XCR1

Antibody type

Monoclonal

Description

XCR1, also known as GPR5 or CCXCR1, is a 38 kD G-protein coupled, seven transmembrane receptor. It is the only member of the "C" chemokine receptor family and mediates chemotaxis of XCL1 and XCL2 (lymphotactin-1 and -2). XCR1 is expressed on a subset of CD141⁺ conventional dendritic cells. XCR1 is also involved in the migration and proliferation of some cancer cells.

Reactivity

Human

Host

Rat

Conjugate

Yellow dye

Antibody clone number

S15046E

Vial size

25 tests

Storage

2°C-8°C

Handling

Ambient RT

Flow cytometry

Supportive validation

Submitted by

BioLegend (provider)

Main image

Experimental details

Human peripheral blood cells were stained with CD14 Brilliant Violet 421™, CD141 APC and XCR1 (clone S15046E) PE (top) or rat IgG2a, κ PE isotype control (bottom). Data shown was gated on the CD14^- population; the gate in the dot plot denotes XCR1⁺ cells.

Conjugate

Yellow dye