Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
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Validation data
Reference
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- Product number
- 24550-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- AMOT antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated AMOT antibody (Cat. #24550-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Microtubule architecture connects AMOT stability to YAP/TAZ mechanotransduction and Hippo signalling.
STUPPIT is a proximity labeling tool for labeling intermediary proteins that bridge two non-interacting proteins.
PSAT1 promotes the progression of colorectal cancer by regulating Hippo-YAP/TAZ-ID1 axis via AMOT.
Regulation of YAP and Wnt signaling by the endosomal protein MAMDC4.
MAGI1 inhibits the AMOTL2/p38 stress pathway and prevents luminal breast tumorigenesis.
The WW domains dictate isoform-specific regulation of YAP1 stability and pancreatic cancer cell malignancy.
Vanni G, Citron A, Suli A, Contessotto P, Caire R, Gandin A, Mantovan G, Zanconato F, Brusatin G, Di Palma M, Peirano E, Pozzer LS, Albanese C Jr, Steiner RA, Cordenonsi M, Panciera T, Piccolo S
Nature cell biology 2025 Oct;27(10):1725-1738
Nature cell biology 2025 Oct;27(10):1725-1738
STUPPIT is a proximity labeling tool for labeling intermediary proteins that bridge two non-interacting proteins.
Xie L, Gao L, Fu W, Wu G, Li H, Ning W
PLoS biology 2025 Nov;23(11):e3003227
PLoS biology 2025 Nov;23(11):e3003227
PSAT1 promotes the progression of colorectal cancer by regulating Hippo-YAP/TAZ-ID1 axis via AMOT.
Tang M, Song K, Xie D, Yuan X, Wang Y, Li Z, Lu X, Guo L, Zhu X, Xiong L, Zhou W, Lin J
Molecular and cellular biochemistry 2025 Jun;480(6):3647-3668
Molecular and cellular biochemistry 2025 Jun;480(6):3647-3668
Regulation of YAP and Wnt signaling by the endosomal protein MAMDC4.
Cox CM, Wu MH, Padilla-Rodriguez M, Blum I, Momtaz S, Mitchell SAT, Wilson JM
PloS one 2024;19(5):e0296003
PloS one 2024;19(5):e0296003
MAGI1 inhibits the AMOTL2/p38 stress pathway and prevents luminal breast tumorigenesis.
Kantar D, Mur EB, Mancini M, Slaninova V, Salah YB, Costa L, Forest E, Lassus P, Géminard C, Boissière-Michot F, Orsetti B, Theillet C, Colinge J, Benistant C, Maraver A, Heron-Milhavet L, Djiane A
Scientific reports 2021 Mar 11;11(1):5752
Scientific reports 2021 Mar 11;11(1):5752
The WW domains dictate isoform-specific regulation of YAP1 stability and pancreatic cancer cell malignancy.
Guo Q, Quan M, Dong J, Bai J, Wang J, Han R, Wang W, Cai Y, Lv YQ, Chen Q, Xu H, Lyu HD, Deng L, Zhou D, Xiao X, De Langhe S, Billadeau DD, Lou Z, Zhang JS
Theranostics 2020;10(10):4422-4436
Theranostics 2020;10(10):4422-4436
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- WB results of 24550-1-AP (1:1000) with over-expressed AMOT by Customer.
- Validation comment
- WB
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- IP Result of anti-AMOT (IP:24550-1-AP, 4ug; Detection:24550-1-AP 1:300) with HEK-293 cells lysate 2500ug.
- Validation comment
- IP