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- References [12]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 21933-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- Sclerostin antibody
- Antibody type
- Polyclonal
- Description
- Sclerostin antibody (Cat. #21933-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Colchicine Blocks Abdominal Aortic Aneurysm Development by Maintaining Vascular Smooth Muscle Cell Homeostasis.
An integrated multi-omics analysis reveals osteokines involved in global regulation.
Hydroxyapatite Nanoparticles Promote the Development of Bone Microtissues for Accelerated Bone Regeneration by Activating the FAK/Akt Pathway.
Notch1 is a marker for in situ resting osteocytes in a 3-dimensional gel culture model.
Lysyl oxidase inhibits BMP9-induced osteoblastic differentiation through reducing Wnt/β-catenin via HIF-1a repression in 3T3-L1 cells.
Inhibition of RANKL Expression in Osteocyte-like Differentiated Tumor Cells in Giant Cell Tumor of Bone After Denosumab Treatment.
Sclerostin Suppression Facilitates Uveal Melanoma Progression Through Activating Wnt/β-Catenin Signaling Via Binding to Membrane Receptors LRP5/LRP6.
Sigma-1 receptor attenuates osteoclastogenesis by promoting ER-associated degradation of SERCA2.
Mechanisms of sphingosine-1-phosphate (S1P) signaling on excessive stress-induced root resorption during orthodontic molar intrusion.
The role of EphB4/ephrinB2 signaling in root repair after orthodontically-induced root resorption.
Cyclooxygenase-2/sclerostin mediates TGF-β1-induced calcification in vascular smooth muscle cells and rats undergoing renal failure.
Higher Sclerostin/SOST expression is associated with lower percentage of circulatory blasts and better prognosis in patients with myelofibrosis.
Chen M, Yang D, Zhou Y, Yang C, Lin W, Li J, Liu J, Ye J, Huang W, Ma W, Li W, Chen J, Zhang Y, Shi GP, Luo J, Li J, Luo S
International journal of biological sciences 2024;20(6):2092-2110
International journal of biological sciences 2024;20(6):2092-2110
An integrated multi-omics analysis reveals osteokines involved in global regulation.
Liang W, Wei T, Hu L, Chen M, Tong L, Zhou W, Duan X, Zhao X, Zhou W, Jiang Q, Xiao G, Zou W, Chen D, Zou Z, Bai X
Cell metabolism 2024 May 7;36(5):1144-1163.e7
Cell metabolism 2024 May 7;36(5):1144-1163.e7
Hydroxyapatite Nanoparticles Promote the Development of Bone Microtissues for Accelerated Bone Regeneration by Activating the FAK/Akt Pathway.
Li L, Li H, Wang Q, Xue Y, Dai Y, Dong Y, Shao M, Lyu F
ACS biomaterials science & engineering 2024 Jul 8;10(7):4463-4479
ACS biomaterials science & engineering 2024 Jul 8;10(7):4463-4479
Notch1 is a marker for in situ resting osteocytes in a 3-dimensional gel culture model.
Zhou YH, Zhu JY, Guo Y, Tang HN, Wang F, Iqbal J, Wu HX, Hu N, Xiao F, Wang T, Li L, Zhou HD
Connective tissue research 2023 Sep;64(5):491-504
Connective tissue research 2023 Sep;64(5):491-504
Lysyl oxidase inhibits BMP9-induced osteoblastic differentiation through reducing Wnt/β-catenin via HIF-1a repression in 3T3-L1 cells.
Zhang J, Ye F, Ye A, He B
Journal of orthopaedic surgery and research 2023 Nov 29;18(1):911
Journal of orthopaedic surgery and research 2023 Nov 29;18(1):911
Inhibition of RANKL Expression in Osteocyte-like Differentiated Tumor Cells in Giant Cell Tumor of Bone After Denosumab Treatment.
Noguchi T, Sakamoto A, Murotani Y, Murata K, Hirata M, Yamada Y, Toguchida J, Matsuda S
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2023 Mar;71(3):131-138
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2023 Mar;71(3):131-138
Sclerostin Suppression Facilitates Uveal Melanoma Progression Through Activating Wnt/β-Catenin Signaling Via Binding to Membrane Receptors LRP5/LRP6.
Wang H, Zhao S, Liu Y, Sun F, Huang X, Wu T
Frontiers in oncology 2022;12:898047
Frontiers in oncology 2022;12:898047
Sigma-1 receptor attenuates osteoclastogenesis by promoting ER-associated degradation of SERCA2.
Wei X, Zheng Z, Feng Z, Zheng L, Tao S, Zheng B, Huang B, Zhang X, Liu J, Chen Y, Zong W, Shan Z, Fan S, Chen J, Zhao F
EMBO molecular medicine 2022 Jul 7;14(7):e15373
EMBO molecular medicine 2022 Jul 7;14(7):e15373
Mechanisms of sphingosine-1-phosphate (S1P) signaling on excessive stress-induced root resorption during orthodontic molar intrusion.
Wang H, Li T, Wang X, Guan Y, Jiang Y, Chen S, Zou S, Duan P
Clinical oral investigations 2022 Jan;26(1):1003-1016
Clinical oral investigations 2022 Jan;26(1):1003-1016
The role of EphB4/ephrinB2 signaling in root repair after orthodontically-induced root resorption.
Li T, Wang H, Liu R, Wang X, Huang L, Wu Z, Yin X, Zou S, Duan P
American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 2021 Mar;159(3):e217-e232
American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 2021 Mar;159(3):e217-e232
Cyclooxygenase-2/sclerostin mediates TGF-β1-induced calcification in vascular smooth muscle cells and rats undergoing renal failure.
He F, Li L, Li PP, Deng Y, Yang YY, Deng YX, Luo HH, Yao XT, Su YX, Gan H, He BC
Aging 2020 Nov 6;12(21):21220-21235
Aging 2020 Nov 6;12(21):21220-21235
Higher Sclerostin/SOST expression is associated with lower percentage of circulatory blasts and better prognosis in patients with myelofibrosis.
Lucijanic M, Livun A, Tupek KM, Stoos-Veic T, Pejsa V, Kusec R
Annals of hematology 2018 Jul;97(7):1293-1294
Annals of hematology 2018 Jul;97(7):1293-1294
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with 21933-1-AP( SOST Antibody) at dilution of 1:1000
- Other comments
- WB
Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SOST antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human SOST. This antibody recognizes human antigen. The SOST antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemistry of paraffin-embedded human liver tissue slide using 21933-1-AP( SOST Antibody) at dilution of 1:50 (under 10x lens)
- Other comments
- IHC
