Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 17073-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17073-1-AP, RRID:AB_10950400
- Product name
- LZTFL1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated LZTFL1 antibody (Cat. #17073-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references LZTFL1 inhibits kidney tumor cell growth by destabilizing AKT through ZNRF1-mediated ubiquitin proteosome pathway.
Rabl2 GTP hydrolysis licenses BBSome-mediated export to fine-tune ciliary signaling.
Ubiquitin links smoothened to intraflagellar transport to regulate Hedgehog signaling.
IFT27 links the BBSome to IFT for maintenance of the ciliary signaling compartment.
Lu J, Fu LM, Cao Y, Fang Y, Cao JZ, Pan YH, Cen JJ, Liang YP, Chen ZH, Wei JH, Huang Y, Mumin MA, Xu QH, Wang YH, Zhu JQ, Liang H, Wang Z, Deng Q, Chen W, Jin XH, Liu ZP, Luo JH
Oncogene 2023 May;42(19):1543-1557
Oncogene 2023 May;42(19):1543-1557
Rabl2 GTP hydrolysis licenses BBSome-mediated export to fine-tune ciliary signaling.
Duan S, Li H, Zhang Y, Yang S, Chen Y, Qiu B, Huang C, Wang J, Li J, Zhu X, Yan X
The EMBO journal 2021 Jan 15;40(2):e105499
The EMBO journal 2021 Jan 15;40(2):e105499
Ubiquitin links smoothened to intraflagellar transport to regulate Hedgehog signaling.
Desai PB, Stuck MW, Lv B, Pazour GJ
The Journal of cell biology 2020 Jul 6;219(7)
The Journal of cell biology 2020 Jul 6;219(7)
IFT27 links the BBSome to IFT for maintenance of the ciliary signaling compartment.
Eguether T, San Agustin JT, Keady BT, Jonassen JA, Liang Y, Francis R, Tobita K, Johnson CA, Abdelhamed ZA, Lo CW, Pazour GJ
Developmental cell 2014 Nov 10;31(3):279-290
Developmental cell 2014 Nov 10;31(3):279-290
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human testis tissue were subjected to SDS PAGE followed by western blot with 17073-1-AP(LZTFL1 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The LZTFL1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human LZTFL1. This antibody recognizes human,mouse,rat antigen. The LZTFL1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.