Tissue expression
Cell line expression
Protein structure
HCST
Hematopoietic cell signal transducerDAP10, DKFZP586C1522, KAP10, PIK3AP
This gene encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Top validated antibodies |
|||||
Novus Biologicals | NB100-55403 | 1 references | Polyclonal |
WB
EL |
|
Invitrogen Antibodies | BS-15430R | Polyclonal |
WB
EL
IHC
FC |
||
antibodies-online | ABIN188679 | 1 references | Polyclonal |
WB
EL |
|
Abnova Corporation | PAB7141 | 1 references | Polyclonal |
WB
|
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider