14898-1-AP

antibody from Proteintech Group

Targeting: NAP1L1 MGC23410, MGC8688, NAP1, NAP1L, NRP

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

14898-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#14898-1-AP, RRID:AB_2150696

Product name

NAP1L1 antibody

Antibody type

Polyclonal

Description

KD/KO validated NAP1L1 antibody (Cat. #14898-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Restricting intracellular Salmonella proliferation by coordinating p-TBK1 mediated mitophagy and xenophagy.

Li J, Yang Y, Ge Y, Zhang X, Liu H, Chen Y, Yang Y, Wu Z
Autophagy 2026 Mar;22(3):445-467

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Long noncoding RNA AC007637.1 inhibits tumorigenesis by regulating the Trim25/PCNA axis in colorectal cancer.

Wang X, Li J, Hao C, Cui K, Tian L, Zhao J, Li C, Feng Y, Yao S, Fei B, Mao X, Huang Z
Journal of advanced research 2026 Apr 6;

---

Tucatinib alleviates postmenopausal osteoporosis by suppressing osteoclast differentiation via regulating the DRP1/NFATc1/CTSK signaling pathway.

Liu X, Liu S, Xu G, Chen W, Shi Y, Wang G, Cao Y, Lu G, Ning Y, Zhao Y
Biochemical pharmacology 2026 Apr 12;250(Pt 1):117962

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NAP1L1 degradation by FBXW7 reduces the deubiquitination of HDGF-p62 signaling to stimulate autophagy and induce primary cisplatin chemosensitivity in nasopharyngeal carcinoma.

Gong B, Liu Y, Yan W, Cheng C, Yang H, Huang J, Liu Q, Liu Y, Guo J, Deng X, Zhou B, Zheng D, Liu X, Liu Z, Fang W
Molecular cancer 2025 May 26;24(1):152

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Effects of polystyrene microparticles exposures on spermatogenic cell differentiation and reproductive endpoints in male mice.

Shen R, Xia P, Guo Y, Ji P, Yuan X, Wang L, Shuang S, Zhou L, Tong R, Zhang L, Liu D, Wang D
Environmental pollution (Barking, Essex : 1987) 2025 May 15;373:126200

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Nucleosome assembly protein-like 1 degradation-dependent novel cardioprotection mechanism of Wnt2 against ischemia‒reperfusion injury.

Wang Y, Chen L, Lin J, Liu X, Jin K, Huang C, Wang H, Jia J, Wu J, Ding Z, Gao P, Ge J, Gong H, Zou Y
Signal transduction and targeted therapy 2025 Dec 16;10(1):403

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NAP1L1 is a novel microtubule-associated protein.

Peng N, Zhang Y, Zhang X, Wu HY, Nakamura F
Cytoskeleton (Hoboken, N.J.) 2023 Sep-Oct;80(9-10):382-392

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Whole exome sequencing in unexplained recurrent miscarriage families identified novel pathogenic genetic causes of euploid miscarriage.

Wang X, Shi W, Zhao S, Gong D, Li S, Hu C, Chen ZJ, Li Y, Yan J
Human reproduction (Oxford, England) 2023 May 2;38(5):1003-1018

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CRISPR-assisted transcription activation by phase-separation proteins.

Liu J, Chen Y, Nong B, Luo X, Cui K, Li Z, Zhang P, Tan W, Yang Y, Ma W, Liang P, Songyang Z
Protein & cell 2023 Dec 1;14(12):874-887

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Mechanism of client selection by the protein quality-control factor UBE2O.

Yip MCJ, Sedor SF, Shao S
Nature structural & molecular biology 2022 Aug;29(8):774-780

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NAP1L1 Functions as a Tumor Promoter via Recruiting Hepatoma-Derived Growth Factor/c-Jun Signal in Hepatocellular Carcinoma.

Zhang YW, Chen Q, Li B, Li HY, Zhao XK, Xiao YY, Liu S, Zuo S
Frontiers in cell and developmental biology 2021;9:659680

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NAP1L1 interacts with hepatoma-derived growth factor to recruit c-Jun inducing breast cancer growth.

Liu S, Zhang Y, Cui S, Song D, Li B, Chen Q, Yao G, Gong B
Cancer cell international 2021 Nov 13;21(1):605

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NAP1L1 and NAP1L4 Binding to Hypervariable Domain of Chikungunya Virus nsP3 Protein Is Bivalent and Requires Phosphorylation.

Dominguez F, Shiliaev N, Lukash T, Agback P, Palchevska O, Gould JR, Meshram CD, Prevelige PE, Green TJ, Agback T, Frolova EI, Frolov I
Journal of virology 2021 Jul 26;95(16):e0083621

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Nucleosome assembly protein 1-like 4, a new therapeutic target for proliferation and invasion of melanoma cells.

Mizuhashi S, Fukushima S, Ishibashi T, Kuriyama H, Kimura T, Kanemaru H, Kajihara I, Makino K, Miyashita A, Aoi J, Kita K, Ihn H
Journal of dermatological science 2021 Apr;102(1):16-24

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Nucleosome Assembly Protein 1-Like 1 (Nap1l1) Regulates the Proliferation of Murine Induced Pluripotent Stem Cells.

Yan Y, Yin P, Gong H, Xue Y, Zhang G, Fang B, Chen Z, Li Y, Yang C, Huang Z, Yang X, Ge J, Zou Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;38(1):340-50

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Quantitative proteomics reveals molecular mechanism of gamabufotalin and its potential inhibition on Hsp90 in lung cancer.

Zhang L, Yu Z, Wang Y, Wang X, Zhang L, Wang C, Yue Q, Wang X, Deng S, Huo X, Tian X, Huang S, Zhang B, Ma X
Oncotarget 2016 Nov 22;7(47):76551-76564

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Jurkat cells were subjected to SDS PAGE followed by western blot with 14898-1-AP(NAP1L1 antibody) at dilution of 1:500

Sample type

cell line

Immunocytochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunofluorescent analysis of MCF-7 cells, using NAP1L1 antibody 14898-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).

Sample type

cell line

Immunohistochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human testis using 14898-1-AP(NAP1L1 antibody) at dilution of 1:50 (under 10x lens)

Sample type

tissue

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human testis using 14898-1-AP(NAP1L1 antibody) at dilution of 1:50 (under 40x lens)

Sample type

tissue