BS7153

antibody from Bioworld Technology, Inc
Targeting: CHRM5
Provider product page for BS7153
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS7153 - Provider product page
Provider
Bioworld Technology, Inc
Product name
mAChR M5 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human mAChR M5.
Description
The muscarinic acetylcholine receptors (mAChR) mediate a variety of cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels. The mAChRs transducer signals by coupling to G-proteins, which then modulate several downstream effector proteins and ion channels. Five mAChR subtypes have been identified, designated M1 to M5. The five receptor subtypes show distinct patterns of tissue distribution, as well as distinct pharmacological and functional properties. The amino acid sequence of each mAChR subtype reflects a structure that is characteristic of G-protein coupled receptors, consisting of seven highly conserved transmembrane segments and a large intracellular region unique to each subtype, which constitutes the effector-coupling domain.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CHRM5 protein structure - BS7153 shown in red.