Tissue expression
Cell line expression

PNPLA1

gene product
dJ50J22.1, FLJ38755 
The protein encoded by this gene belongs to the patatin-like phospholipase (PNPLA) family, which is characterized by the presence of a highly conserved patatin domain. PNPLA family members have diverse lipolytic and acyltransferase activities, and are key elements in lipid metabolism. While other members of this family have been well characterized, the function of this gene remained an enigma. However, recent studies show that this gene is expressed in the skin epidermal keratinocytes, and has a role in glycerophospholipid metabolism in the cutaneous barrier. Consistent with these observations, mutations in this gene are associated with ichthyosis in human (autosomal recessive congenital ichthyoses, ARCI) and dog. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
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130 antibodies from 17 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
2 antibodies
Cusabio Biotech Co., Ltd
4 antibodies
antibodies-online
48 antibodies
Biorbyt
9 antibodies
Novus Biologicals
2 antibodies
Abnova Corporation
2 antibodies
LifeSpan BioSciences, Inc.
21 antibodies
Aviva Systems Biology
2 antibodies
Abgent
1 antibody
GeneTex
1 antibody
OriGene
1 antibody
Abbexa
5 antibodies
Creative Diagnostics
2 antibodies
MyBioSource
1 antibody
United States Biological
13 antibodies
MilliporeSigma / Merck KGaA
1 antibody