Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 14027-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14027-1-AP, RRID:AB_2182321
- Product name
- ROD1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ROD1 antibody (Cat. #14027-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Polypyrimidine tract-binding protein 3/insulin-like growth factor 2 mRNA-binding proteins 3/high-mobility group A1 axis promotes renal cancer growth and metastasis.
PTBP1-activated co-transcriptional splicing controls epigenetic status of pluripotent stem cells.
PTBP3 regulates proliferation of lung squamous cell carcinoma cells via CDC25A-mediated cell cycle progression.
PTBP3 promotes migration of non-small cell lung cancer through regulating E-cadherin in EMT signaling pathway.
The RNA-binding protein ROD1/PTBP3 cotranscriptionally defines AID-loading sites to mediate antibody class switch in mammalian genomes.
Overexpression of ROD1 inhibits invasion of breast cancer cells by suppressing the translocation of β-catenin into the nucleus.
Wang Q, Chen F, He Y, Gao Y, Wang J, Chu S, Xie P, Zhong J, Shan H, Bai J, Hou P
iScience 2024 Mar 15;27(3):109158
iScience 2024 Mar 15;27(3):109158
PTBP1-activated co-transcriptional splicing controls epigenetic status of pluripotent stem cells.
Iannone C, Kainov Y, Zhuravskaya A, Hamid F, Nojima T, Makeyev EV
Molecular cell 2023 Jan 19;83(2):203-218.e9
Molecular cell 2023 Jan 19;83(2):203-218.e9
PTBP3 regulates proliferation of lung squamous cell carcinoma cells via CDC25A-mediated cell cycle progression.
Chen Y, Ji Y, Liu S, Liu Y, Feng W, Jin L
Cancer cell international 2022 Jan 11;22(1):19
Cancer cell international 2022 Jan 11;22(1):19
PTBP3 promotes migration of non-small cell lung cancer through regulating E-cadherin in EMT signaling pathway.
Wu Q, Zhang B, Li B, Cao X, Chen X, Xue Q
Cancer cell international 2020;20:172
Cancer cell international 2020;20:172
The RNA-binding protein ROD1/PTBP3 cotranscriptionally defines AID-loading sites to mediate antibody class switch in mammalian genomes.
Chen J, Cai Z, Bai M, Yu X, Zhang C, Cao C, Hu X, Wang L, Su R, Wang D, Wang L, Yao Y, Ye R, Hou B, Yu Y, Yu S, Li J, Xue Y
Cell research 2018 Oct;28(10):981-995
Cell research 2018 Oct;28(10):981-995
Overexpression of ROD1 inhibits invasion of breast cancer cells by suppressing the translocation of β-catenin into the nucleus.
Zhou Y, Zou H, Wu E, Huang L, Yin R, Mei Y, Zhu X
Oncology letters 2018 Aug;16(2):2645-2653
Oncology letters 2018 Aug;16(2):2645-2653
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HL-60 cells were subjected to SDS PAGE followed by western blot with 14027-1-AP(ROD1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lymphoma using 14027-1-AP(ROD1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ROD1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ROD1. This antibody recognizes human, mouse, rat antigen. The ROD1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.