Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 17737-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17737-1-AP, RRID:AB_10665813
- Product name
- EDC4 antibody
- Antibody type
- Polyclonal
- Description
- EDC4 antibody (Cat. #17737-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Pooled CRISPR Screening Identifies P-Bodies as Repressors of Cancer Epithelial-Mesenchymal Transition.
DDX6 modulates P-body and stress granule assembly, composition, and docking.
LSM14B coordinates protein component expression in the P-body and controls oocyte maturation.
A protein-proximity screen reveals Ebola virus co-opts the mRNA decapping complex through the scaffold protein EDC4.
O-GlcNAcylation determines the translational regulation and phase separation of YTHDF proteins.
Proteomic profiling of centrosomes across multiple mammalian cell and tissue types by an affinity capture method.
NUSAP1 regulates mouse oocyte meiotic maturation.
QKI degradation in macrophage by RNF6 protects mice from MRSA infection via enhancing PI3K p110β dependent autophagy.
The RNA binding protein QKI5 suppresses ovarian cancer via downregulating transcriptional coactivator TAZ.
Gemin5 plays a role in unassembled-U1 snRNA disposal in SMN-deficient cells.
Fang L, Zhang L, Wang M, He Y, Yang J, Huang Z, Tan Y, Fang K, Li J, Sun Z, Li Y, Tang Y, Liang W, Cui H, Zhu Q, Wu Z, Li Y, Hu Y, Chen W
Cancer research 2024 Mar 4;84(5):659-674
Cancer research 2024 Mar 4;84(5):659-674
DDX6 modulates P-body and stress granule assembly, composition, and docking.
Ripin N, Macedo de Vasconcelos L, Ugay DA, Parker R
The Journal of cell biology 2024 Jun 3;223(6)
The Journal of cell biology 2024 Jun 3;223(6)
LSM14B coordinates protein component expression in the P-body and controls oocyte maturation.
Zhang H, Zhang T, Wan X, Chen C, Wang S, Qin D, Li L, Yu L, Wu X
Journal of genetics and genomics = Yi chuan xue bao 2024 Jan;51(1):48-60
Journal of genetics and genomics = Yi chuan xue bao 2024 Jan;51(1):48-60
A protein-proximity screen reveals Ebola virus co-opts the mRNA decapping complex through the scaffold protein EDC4.
Davey R, Donahue C, Kesari A, Thakur N, Wang L, Hulsey-Stubbs S, Williams C, Kirby C, Leung D, Aryal U, Basler C, LaCount D
Research square 2024 Feb 2;
Research square 2024 Feb 2;
O-GlcNAcylation determines the translational regulation and phase separation of YTHDF proteins.
Chen Y, Wan R, Zou Z, Lao L, Shao G, Zheng Y, Tang L, Yuan Y, Ge Y, He C, Lin S
Nature cell biology 2023 Nov;25(11):1676-1690
Nature cell biology 2023 Nov;25(11):1676-1690
Proteomic profiling of centrosomes across multiple mammalian cell and tissue types by an affinity capture method.
Carden S, Vitiello E, Rosa E Silva I, Holder J, Quarantotti V, Kishore K, Roamio Franklin VN, D'Santos C, Ochi T, van Breugel M, Gergely F
Developmental cell 2023 Nov 6;58(21):2393-2410.e9
Developmental cell 2023 Nov 6;58(21):2393-2410.e9
NUSAP1 regulates mouse oocyte meiotic maturation.
Yu L, Kong N, Lin Y, Qiu P, Xu Q, Zhang Y, Zhen X, Yan G, Sun H, Mei J, Cao G
Journal of cellular biochemistry 2023 Dec;124(12):1931-1947
Journal of cellular biochemistry 2023 Dec;124(12):1931-1947
QKI degradation in macrophage by RNF6 protects mice from MRSA infection via enhancing PI3K p110β dependent autophagy.
Zhai D, Wang W, Ye Z, Xue K, Chen G, Hu S, Yan Z, Guo Y, Wang F, Li X, Xiang A, Li X, Lu Z, Wang L
Cell & bioscience 2022 Sep 10;12(1):154
Cell & bioscience 2022 Sep 10;12(1):154
The RNA binding protein QKI5 suppresses ovarian cancer via downregulating transcriptional coactivator TAZ.
Liu T, Yang Y, Xie Z, Luo Q, Yang D, Liu X, Zhao H, Wei Q, Liu Y, Li L, Wang Y, Wang F, Yu J, Xu J, Yu J, Yi P
Molecular therapy. Nucleic acids 2021 Dec 3;26:388-400
Molecular therapy. Nucleic acids 2021 Dec 3;26:388-400
Gemin5 plays a role in unassembled-U1 snRNA disposal in SMN-deficient cells.
Jiang D, Zou X, Zhang C, Chen J, Li Z, Wang Y, Deng Z, Wang L, Chen S
FEBS letters 2018 Apr;592(8):1400-1411
FEBS letters 2018 Apr;592(8):1400-1411
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 17737-1-AP(EDC4 antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver cancer using 17737-1-AP(EDC4 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The EDC4 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human EDC4. This antibody recognizes human,mouse,rat antigen. The EDC4 antibody has been validated for the following applications: ELISA, WB, IHC analysis.