Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- ABIN1981892 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Complement Component 5a Receptor 1 (C5AR1) (AA 15-27), (N-Term) antibody (PE)
- Antibody type
- Monoclonal
- Reactivity
- Human, Bovine, Rabbit
- Host
- Mouse
- Conjugate
- Yellow dye
- Epitope
- AA 15-27, N-Term
- Isotype
- IgG
- Antibody clone number
- S5-1
- Vial size
- 100 tests
- Storage
- Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
- Handling
- Do not freeze. Avoid prolonged exposure to light.Do not use after expiration date stamped on vial label. Short-term exposure to room temperature should not affect the quality of the reagent. However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user.
Submitted references Complement alternative pathway acts as a positive feedback amplification of neutrophil activation.
C5a mediates peripheral blood neutrophil dysfunction in critically ill patients.
The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74).
Expression of the C5a receptor (CD88) on synovial mast cells in patients with rheumatoid arthritis.
Camous L, Roumenina L, Bigot S, Brachemi S, Frémeaux-Bacchi V, Lesavre P, Halbwachs-Mecarelli L
Blood 2011 Jan 27;117(4):1340-9
Blood 2011 Jan 27;117(4):1340-9
C5a mediates peripheral blood neutrophil dysfunction in critically ill patients.
Conway Morris A, Kefala K, Wilkinson TS, Dhaliwal K, Farrell L, Walsh T, Mackenzie SJ, Reid H, Davidson DJ, Haslett C, Rossi AG, Sallenave JM, Simpson AJ
American journal of respiratory and critical care medicine 2009 Jul 1;180(1):19-28
American journal of respiratory and critical care medicine 2009 Jul 1;180(1):19-28
The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74).
Cain SA, Monk PN
The Journal of biological chemistry 2002 Mar 1;277(9):7165-9
The Journal of biological chemistry 2002 Mar 1;277(9):7165-9
Expression of the C5a receptor (CD88) on synovial mast cells in patients with rheumatoid arthritis.
Kiener HP, Baghestanian M, Dominkus M, Walchshofer S, Ghannadan M, Willheim M, Sillaber C, Graninger WB, Smolen JS, Valent P
Arthritis and rheumatism 1998 Feb;41(2):233-45
Arthritis and rheumatism 1998 Feb;41(2):233-45
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