344304

antibody from BioLegend

Targeting: C5AR1 C5A, C5AR, C5R1, CD88

Antibody data

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Validation data

Product number: 344304 - Provider product page
Provider: BioLegend
Proper citation: BioLegend Cat#344304, RRID:AB_2067175
Product name: PE anti-human CD88 (C5aR)
Antibody type: Monoclonal
Antigen: Recombinant peptide huC5aR N-terminal -NT (Asp15-Asp27)
Description: CD88 is a single chain protein with seven membrane-spanning regions and has a MW of 43 kD. CD88 is expressed by monocytes, neutrophils and eosinophils. Also, there have been reports of CD88 expression in non-immune cells such as glial cells, cerebellar granule cells, cardiomyocytes and vascular endothelial cells. CD88 is coupled to heterotrimeric G proteins such as Gi, and after C5a binding, the signal transduced by CD88 results in the activation of PLCβ, PI-3 kinase, and PLA2, among other molecules, resulting in chemotaxis, granule enzyme release and superoxide anion production.
Reactivity: Human
Host: Mouse
Conjugate: Yellow dye
Isotype: IgG
Vial size: 100 tests
Storage: The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

C5AR1 protein structure - 344304 shown in red.