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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [6]
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- Product number
- ABIN951421 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Complement Component 5a Receptor 1 (C5AR1) antibody
- Antibody type
- Monoclonal
- Description
- Affinity chromatography on Protein G
- Reactivity
- Human
- Host
- Rat
- Isotype
- IgG
- Antibody clone number
- 8D6
- Vial size
- 0.25 mg
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Use of monoclonal antibodies to assess expression of anaphylatoxin receptors in tubular epithelial cells of human, murine and rat kidneys.
Up-regulation of C5a receptor expression and function on human monocyte derived dendritic cells by prostaglandin E2.
Expression of the anaphylatoxin C5a receptor in non-myeloid cells.
C5a receptor and interleukin-6 are expressed in tissue macrophages and stimulated keratinocytes but not in pulmonary and intestinal epithelial cells.
C5a receptors are detectable on mast cells in normal human skin and in psoriatic plaques but not in weal and flare reactions or in uticaria pigmentosa by immunohistochemistry.
CD88 antibodies specifically bind to C5aR on dermal CD117+ and CD14+ cells and react with a desmosomal antigen in human skin.
Kiafard Z, Tschernig T, Schweyer S, Bley A, Neumann D, Zwirner J
Immunobiology 2007;212(2):129-39
Immunobiology 2007;212(2):129-39
Up-regulation of C5a receptor expression and function on human monocyte derived dendritic cells by prostaglandin E2.
Weinmann O, Gutzmer R, Zwirner J, Wittmann M, Langer K, Lisewski M, Mommert S, Kapp A, Werfel T
Immunology 2003 Dec;110(4):458-65
Immunology 2003 Dec;110(4):458-65
Expression of the anaphylatoxin C5a receptor in non-myeloid cells.
Zwirner J, Fayyazi A, Götze O
Molecular immunology 1999 Sep-Oct;36(13-14):877-84
Molecular immunology 1999 Sep-Oct;36(13-14):877-84
C5a receptor and interleukin-6 are expressed in tissue macrophages and stimulated keratinocytes but not in pulmonary and intestinal epithelial cells.
Fayyazi A, Sandau R, Duong LQ, Götze O, Radzun HJ, Schweyer S, Soruri A, Zwirner J
The American journal of pathology 1999 Feb;154(2):495-501
The American journal of pathology 1999 Feb;154(2):495-501
C5a receptors are detectable on mast cells in normal human skin and in psoriatic plaques but not in weal and flare reactions or in uticaria pigmentosa by immunohistochemistry.
Werfel T, Oppermann M, Begemann G, Götze O, Zwirner J
Archives of dermatological research 1997 Jan;289(2):83-6
Archives of dermatological research 1997 Jan;289(2):83-6
CD88 antibodies specifically bind to C5aR on dermal CD117+ and CD14+ cells and react with a desmosomal antigen in human skin.
Werfel T, Zwirner J, Oppermann M, Sieber A, Begemann G, Drommer W, Kapp A, Götze O
Journal of immunology (Baltimore, Md. : 1950) 1996 Aug 15;157(4):1729-35
Journal of immunology (Baltimore, Md. : 1950) 1996 Aug 15;157(4):1729-35
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