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Learn16153-1-AP
antibody from Proteintech Group
Targeting: CCR2
CC-CKR-2, CD192, CKR2, CMKBR2, FLJ78302, MCP-1-R
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [18]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 16153-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16153-1-AP, RRID:AB_2262945
- Product name
- CCR2a-specific antibody
- Antibody type
- Polyclonal
- Description
- CCR2a-specific antibody (Cat. #16153-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Myeloid Deletion of Cdc42 Protects Liver From Hepatic Ischemia-Reperfusion Injury via Inhibiting Macrophage-Mediated Inflammation in Mice.
Camouflaging attenuated Salmonella by cryo-shocked macrophages for tumor-targeted therapy.
M2 Macrophage Membrane-Camouflaged Fe(3) O(4) -Cy7 Nanoparticles with Reduced Immunogenicity for Targeted NIR/MR Imaging of Atherosclerosis.
Interleukin-6 trans-signaling regulates monocyte chemoattractant protein-1 production in immune-mediated necrotizing myopathy.
Hypoxia-induced CCL2/CCR2 axis in adipose-derived stem cells (ADSCs) promotes angiogenesis by human dermal microvascular endothelial cells (HDMECs) in flap tissues.
Single-cell RNA sequencing analysis of the temporomandibular joint condyle in 3 and 4-month-old human embryos.
Combination therapy with bevacizumab and a CCR2 inhibitor for human ovarian cancer: An in vivo validation study.
CCL2 activates AKT signaling to promote glycolysis and chemoresistance in glioma cells.
Targeting CCL2-CCR4 axis suppress cell migration of head and neck squamous cell carcinoma.
Identification of potential regulating effect of baicalin on NFκB/CCL2/CCR2 signaling pathway in rats with cerebral ischemia by antibody-based array and bioinformatics analysis.
Eplerenone inhibits the macrophage-to-myofibroblast transition in rats with UUO-induced type 4 cardiorenal syndrome through the MR/CTGF pathway.
QKI deficiency in macrophages protects mice against JEV infection by regulating cell migration and antiviral response.
ZC3H4 regulates infiltrating monocytes, attenuating pulmonary fibrosis through IL-10.
Matrix metalloproteinase 11 (MMP11) in macrophages promotes the migration of HER2-positive breast cancer cells and monocyte recruitment through CCL2-CCR2 signaling.
Curcumin alleviates inflammation in Takayasu's arteritis by blocking CCL2 overexpression in adventitial fibroblasts.
CCL2-CCR2 Axis Potentiates NMDA Receptor Signaling to Aggravate Neuropathic Pain Induced by Brachial Plexus Avulsion.
CCL2 secreted from cancer-associated mesothelial cells promotes peritoneal metastasis of ovarian cancer cells through the P38-MAPK pathway.
CCL2/CCR2 axis induces hepatocellular carcinoma invasion and epithelial-mesenchymal transition in vitro through activation of the Hedgehog pathway.
He J, Tang MY, Liu LX, Kong CX, Chen W, Wang L, Zhi SB, Sun HW, Huang YC, Chen GY, Xin HB, Deng KY
Cellular and molecular gastroenterology and hepatology 2024;17(6):965-981
Cellular and molecular gastroenterology and hepatology 2024;17(6):965-981
Camouflaging attenuated Salmonella by cryo-shocked macrophages for tumor-targeted therapy.
Wu L, Du Z, Li L, Qiao L, Zhang S, Yin X, Chang X, Li C, Hua Z
Signal transduction and targeted therapy 2024 Jan 10;9(1):14
Signal transduction and targeted therapy 2024 Jan 10;9(1):14
M2 Macrophage Membrane-Camouflaged Fe(3) O(4) -Cy7 Nanoparticles with Reduced Immunogenicity for Targeted NIR/MR Imaging of Atherosclerosis.
Zou L, Zhang Y, Cheraga N, Abodunrin OD, Qu KY, Qiao L, Ma YQ, Hang Y, Huang NP, Chen LJ
Small (Weinheim an der Bergstrasse, Germany) 2024 Feb;20(8):e2304110
Small (Weinheim an der Bergstrasse, Germany) 2024 Feb;20(8):e2304110
Interleukin-6 trans-signaling regulates monocyte chemoattractant protein-1 production in immune-mediated necrotizing myopathy.
Ma X, Gao HJ, Ge HZ, Zhang Q, Bu BT
Rheumatology (Oxford, England) 2024 Feb 23;
Rheumatology (Oxford, England) 2024 Feb 23;
Hypoxia-induced CCL2/CCR2 axis in adipose-derived stem cells (ADSCs) promotes angiogenesis by human dermal microvascular endothelial cells (HDMECs) in flap tissues.
Fang B, Wang X, Sun Y, Xiong X, Meng X, Li W, Yi Z
Journal of physiology and biochemistry 2023 May;79(2):327-339
Journal of physiology and biochemistry 2023 May;79(2):327-339
Single-cell RNA sequencing analysis of the temporomandibular joint condyle in 3 and 4-month-old human embryos.
Zhu Q, Tan M, Wang C, Chen Y, Wang C, Zhang J, Gu Y, Guo Y, Han J, Li L, Jiang R, Fan X, Xie H, Wang L, Gu Z, Liu D, Shi J, Feng X
Cell & bioscience 2023 Jul 19;13(1):130
Cell & bioscience 2023 Jul 19;13(1):130
Combination therapy with bevacizumab and a CCR2 inhibitor for human ovarian cancer: An in vivo validation study.
Zhai T, Mitamura T, Wang L, Kubota SI, Murakami M, Tanaka S, Watari H
Cancer medicine 2023 Apr;12(8):9697-9708
Cancer medicine 2023 Apr;12(8):9697-9708
CCL2 activates AKT signaling to promote glycolysis and chemoresistance in glioma cells.
Qian Y, Ding P, Xu J, Nie X, Lu B
Cell biology international 2022 May;46(5):819-828
Cell biology international 2022 May;46(5):819-828
Targeting CCL2-CCR4 axis suppress cell migration of head and neck squamous cell carcinoma.
Ling Z, Li W, Hu J, Li Y, Deng M, Zhang S, Ren X, Wu T, Xia J, Cheng B, Tao X
Cell death & disease 2022 Feb 17;13(2):158
Cell death & disease 2022 Feb 17;13(2):158
Identification of potential regulating effect of baicalin on NFκB/CCL2/CCR2 signaling pathway in rats with cerebral ischemia by antibody-based array and bioinformatics analysis.
Xu T, Wang X, Ma C, Ji J, Xu W, Shao Q, Liao X, Li Y, Cheng F, Wang Q
Journal of ethnopharmacology 2022 Feb 10;284:114773
Journal of ethnopharmacology 2022 Feb 10;284:114773
Eplerenone inhibits the macrophage-to-myofibroblast transition in rats with UUO-induced type 4 cardiorenal syndrome through the MR/CTGF pathway.
Han Y, Xian Y, Gao X, Qiang P, Hao J, Yang F, Shimosawa T, Chang Y, Xu Q
International immunopharmacology 2022 Dec;113(Pt A):109396
International immunopharmacology 2022 Dec;113(Pt A):109396
QKI deficiency in macrophages protects mice against JEV infection by regulating cell migration and antiviral response.
Deng L, Wang W, Bian P, Wu M, Wang L, Lei Y, Lu Z, Zhai D
Molecular immunology 2022 Aug;148:34-44
Molecular immunology 2022 Aug;148:34-44
ZC3H4 regulates infiltrating monocytes, attenuating pulmonary fibrosis through IL-10.
Liu Y, Zhang X, Wang J, Yang F, Luo W, Huang J, Chen M, Wang S, Li C, Zhang W, Chao J
Respiratory research 2022 Aug 12;23(1):204
Respiratory research 2022 Aug 12;23(1):204
Matrix metalloproteinase 11 (MMP11) in macrophages promotes the migration of HER2-positive breast cancer cells and monocyte recruitment through CCL2-CCR2 signaling.
Kang SU, Cho SY, Jeong H, Han J, Chae HY, Yang H, Sung CO, Choi YL, Shin YK, Kwon MJ
Laboratory investigation; a journal of technical methods and pathology 2022 Apr;102(4):376-390
Laboratory investigation; a journal of technical methods and pathology 2022 Apr;102(4):376-390
Curcumin alleviates inflammation in Takayasu's arteritis by blocking CCL2 overexpression in adventitial fibroblasts.
Wu S, Kong X, Wang Y, Fan X, Huang Q, Chen R, Yu W, Ma L, Sun Y, Jiang L
Clinical and experimental rheumatology 2021 Mar-Apr;39 Suppl 129(2):161-170
Clinical and experimental rheumatology 2021 Mar-Apr;39 Suppl 129(2):161-170
CCL2-CCR2 Axis Potentiates NMDA Receptor Signaling to Aggravate Neuropathic Pain Induced by Brachial Plexus Avulsion.
Xian H, Jiang Y, Zhang H, Ma SB, Zhao R, Cong R
Neuroscience 2020 Jan 15;425:29-38
Neuroscience 2020 Jan 15;425:29-38
CCL2 secreted from cancer-associated mesothelial cells promotes peritoneal metastasis of ovarian cancer cells through the P38-MAPK pathway.
Yasui H, Kajiyama H, Tamauchi S, Suzuki S, Peng Y, Yoshikawa N, Sugiyama M, Nakamura K, Kikkawa F
Clinical & experimental metastasis 2020 Feb;37(1):145-158
Clinical & experimental metastasis 2020 Feb;37(1):145-158
CCL2/CCR2 axis induces hepatocellular carcinoma invasion and epithelial-mesenchymal transition in vitro through activation of the Hedgehog pathway.
Zhuang H, Cao G, Kou C, Liu T
Oncology reports 2018 Jan;39(1):21-30
Oncology reports 2018 Jan;39(1):21-30
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 16153-1-AP(CCR2a-specific antibody) at dilution of 1:200
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CCR2-specific antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human CCR2-specific. This antibody recognizes human antigen. The CCR2-specific antibody has been validated for the following applications: ELISA, WB, IHC analysis.
