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- Antigen structure
- References [27]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 11663-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11663-1-AP, RRID:AB_2304144
- Product name
- VDAC2 antibody
- Antibody type
- Polyclonal
- Description
- VDAC2 antibody (Cat. #11663-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Biomarker Identification and Risk Prediction Model Development for Differentiated Thyroid Carcinoma Lung Metastasis Based on Primary Lesion Proteomics.
Interactome Analysis Identifies the Role of BZW2 in Promoting Endoplasmic Reticulum-Mitochondria Contact and Mitochondrial Metabolism.
The E3 ubiquitin ligase MARCH2 protects against myocardial ischemia-reperfusion injury through inhibiting pyroptosis via negative regulation of PGAM5/MAVS/NLRP3 axis.
Circular RNA EIF3I promotes papillary thyroid cancer progression by interacting with AUF1 to increase Cyclin D1 production.
Pathological convergence of APP and SNCA deficiency in hippocampal degeneration of young rats.
Interaction between PI3K and the VDAC2 channel tethers Ras-PI3K-positive endosomes to mitochondria and promotes endosome maturation.
De novo pyrimidine biosynthetic complexes support cancer cell proliferation and ferroptosis defence.
Parkin regulates amino acid homeostasis at mitochondria-lysosome (M/L) contact sites in Parkinson's disease.
STING Suppresses Mitochondrial VDAC2 to Govern RCC Growth Independent of Innate Immunity.
Mitochondria regulate intracellular coenzyme Q transport and ferroptotic resistance via STARD7.
The lncRNA BDNF-AS/WDR5/FBXW7 axis mediates ferroptosis in gastric cancer peritoneal metastasis by regulating VDAC3 ubiquitination.
Multi-mtDNA Variants May Be a Factor Contributing to Mitochondrial Function Variety in the Skin-Derived Fibroblasts of Leber's Hereditary Optic Neuropathy Patients.
Herceptin induces ferroptosis and mitochondrial dysfunction in H9c2 cells.
Temporal Analysis of Protein Ubiquitylation and Phosphorylation During Parkin-Dependent Mitophagy.
Kastor and Polluks polypeptides encoded by a single gene locus cooperatively regulate VDAC and spermatogenesis.
SPATA33 is an autophagy mediator for cargo selectivity in germline mitophagy.
Conformational change of adenine nucleotide translocase-1 mediates cisplatin resistance induced by EBV-LMP1.
SPATA33 localizes calcineurin to the mitochondria and regulates sperm motility in mice.
Identification of a new natural biflavonoids against breast cancer cells induced ferroptosis via the mitochondrial pathway.
Heat shock protein 60 regulates yolk sac erythropoiesis in mice.
Quantitative proteomics analysis of the role of tetraspanin-8 in the drug resistance of gastric cancer.
Proteomics-based identification of VDAC1 as a tumor promoter in cervical carcinoma.
Mechanistic Study of the Phytocompound, 2- β -D-Glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-tetrayne in Human T-Cell Acute Lymphocytic Leukemia Cells by Using Combined Differential Proteomics and Bioinformatics Approaches.
MYBL2 guides autophagy suppressor VDAC2 in the developing ovary to inhibit autophagy through a complex of VDAC2-BECN1-BCL2L1 in mammals.
VDAC3 gating is activated by suppression of disulfide-bond formation between the N-terminal region and the bottom of the pore.
Tumor Necrosis Factor-Associated Protein 1 (TRAP1) is Released from the Mitochondria Following 6-hydroxydopamine Treatment.
Identification of sperm head proteins involved in zona pellucida binding.
Peng X, Zhao H, Ye L, Hou F, Yi Z, Ren Y, Lu L, Chen F, Lv J, Wang Y, Cai H, Zheng X, Yang Q, Chen T
Clinical cancer research : an official journal of the American Association for Cancer Research 2024 Jul 15;30(14):3059-3072
Clinical cancer research : an official journal of the American Association for Cancer Research 2024 Jul 15;30(14):3059-3072
Interactome Analysis Identifies the Role of BZW2 in Promoting Endoplasmic Reticulum-Mitochondria Contact and Mitochondrial Metabolism.
Maio G, Smith M, Bhawal R, Zhang S, Baskin JM, Li J, Lin H
Molecular & cellular proteomics : MCP 2024 Feb;23(2):100709
Molecular & cellular proteomics : MCP 2024 Feb;23(2):100709
The E3 ubiquitin ligase MARCH2 protects against myocardial ischemia-reperfusion injury through inhibiting pyroptosis via negative regulation of PGAM5/MAVS/NLRP3 axis.
Liu S, Bi Y, Han T, Li YE, Wang Q, Wu NN, Xu C, Ge J, Hu R, Zhang Y
Cell discovery 2024 Feb 27;10(1):24
Cell discovery 2024 Feb 27;10(1):24
Circular RNA EIF3I promotes papillary thyroid cancer progression by interacting with AUF1 to increase Cyclin D1 production.
Yao X, Liu H, Wang Z, Lu F, Chen W, Feng Q, Miao Y, Zhang J, Wang Y, Chen Y, Xue L, Liu Y, Chen L, Zhang Q
Oncogene 2023 Oct;42(43):3206-3218
Oncogene 2023 Oct;42(43):3206-3218
Pathological convergence of APP and SNCA deficiency in hippocampal degeneration of young rats.
Wang Y, Miao Z, Xu C, Cai Y, Yang Y, Hu Y, Zhao M, Shao Y, Li Z, Chen J, Chen S, Wang L
Cell death & disease 2023 May 13;14(5):325
Cell death & disease 2023 May 13;14(5):325
Interaction between PI3K and the VDAC2 channel tethers Ras-PI3K-positive endosomes to mitochondria and promotes endosome maturation.
Satoh AO, Fujioka Y, Kashiwagi S, Yoshida A, Fujioka M, Sasajima H, Nanbo A, Amano M, Ohba Y
Cell reports 2023 Mar 28;42(3):112229
Cell reports 2023 Mar 28;42(3):112229
De novo pyrimidine biosynthetic complexes support cancer cell proliferation and ferroptosis defence.
Yang C, Zhao Y, Wang L, Guo Z, Ma L, Yang R, Wu Y, Li X, Niu J, Chu Q, Fu Y, Li B
Nature cell biology 2023 Jun;25(6):836-847
Nature cell biology 2023 Jun;25(6):836-847
Parkin regulates amino acid homeostasis at mitochondria-lysosome (M/L) contact sites in Parkinson's disease.
Peng W, Schröder LF, Song P, Wong YC, Krainc D
Science advances 2023 Jul 21;9(29):eadh3347
Science advances 2023 Jul 21;9(29):eadh3347
STING Suppresses Mitochondrial VDAC2 to Govern RCC Growth Independent of Innate Immunity.
Zhu Z, Zhou X, Du H, Cloer EW, Zhang J, Mei L, Wang Y, Tan X, Hepperla AJ, Simon JM, Cook JG, Major MB, Dotti G, Liu P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jan;10(3):e2203718
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jan;10(3):e2203718
Mitochondria regulate intracellular coenzyme Q transport and ferroptotic resistance via STARD7.
Deshwal S, Onishi M, Tatsuta T, Bartsch T, Cors E, Ried K, Lemke K, Nolte H, Giavalisco P, Langer T
Nature cell biology 2023 Feb;25(2):246-257
Nature cell biology 2023 Feb;25(2):246-257
The lncRNA BDNF-AS/WDR5/FBXW7 axis mediates ferroptosis in gastric cancer peritoneal metastasis by regulating VDAC3 ubiquitination.
Huang G, Xiang Z, Wu H, He Q, Dou R, Lin Z, Yang C, Huang S, Song J, Di Z, Wang S, Xiong B
International journal of biological sciences 2022;18(4):1415-1433
International journal of biological sciences 2022;18(4):1415-1433
Multi-mtDNA Variants May Be a Factor Contributing to Mitochondrial Function Variety in the Skin-Derived Fibroblasts of Leber's Hereditary Optic Neuropathy Patients.
Yao S, Zhou Q, Yang M, Li Y, Jin X, Guo Q, Yang L, Qin F, Lei B
Frontiers in molecular neuroscience 2022;15:920221
Frontiers in molecular neuroscience 2022;15:920221
Herceptin induces ferroptosis and mitochondrial dysfunction in H9c2 cells.
Sun L, Wang H, Yu S, Zhang L, Jiang J, Zhou Q
International journal of molecular medicine 2022 Feb;49(2)
International journal of molecular medicine 2022 Feb;49(2)
Temporal Analysis of Protein Ubiquitylation and Phosphorylation During Parkin-Dependent Mitophagy.
Zittlau KI, Lechado-Terradas A, Nalpas N, Geisler S, Kahle PJ, Macek B
Molecular & cellular proteomics : MCP 2022 Feb;21(2):100191
Molecular & cellular proteomics : MCP 2022 Feb;21(2):100191
Kastor and Polluks polypeptides encoded by a single gene locus cooperatively regulate VDAC and spermatogenesis.
Mise S, Matsumoto A, Shimada K, Hosaka T, Takahashi M, Ichihara K, Shimizu H, Shiraishi C, Saito D, Suyama M, Yasuda T, Ide T, Izumi Y, Bamba T, Kimura-Someya T, Shirouzu M, Miyata H, Ikawa M, Nakayama KI
Nature communications 2022 Feb 28;13(1):1071
Nature communications 2022 Feb 28;13(1):1071
SPATA33 is an autophagy mediator for cargo selectivity in germline mitophagy.
Zhang Y, Xu X, Hu M, Wang X, Cheng H, Zhou R
Cell death and differentiation 2021 Mar;28(3):1076-1090
Cell death and differentiation 2021 Mar;28(3):1076-1090
Conformational change of adenine nucleotide translocase-1 mediates cisplatin resistance induced by EBV-LMP1.
Zhao L, Deng X, Li Y, Hu J, Xie L, Shi F, Tang M, Bode AM, Zhang X, Liao W, Cao Y
EMBO molecular medicine 2021 Dec 7;13(12):e14072
EMBO molecular medicine 2021 Dec 7;13(12):e14072
SPATA33 localizes calcineurin to the mitochondria and regulates sperm motility in mice.
Miyata H, Oura S, Morohoshi A, Shimada K, Mashiko D, Oyama Y, Kaneda Y, Matsumura T, Abbasi F, Ikawa M
Proceedings of the National Academy of Sciences of the United States of America 2021 Aug 31;118(35)
Proceedings of the National Academy of Sciences of the United States of America 2021 Aug 31;118(35)
Identification of a new natural biflavonoids against breast cancer cells induced ferroptosis via the mitochondrial pathway.
Xie Y, Zhou X, Li J, Yao XC, Liu WL, Kang FH, Zou ZX, Xu KP, Xu PS, Tan GS
Bioorganic chemistry 2021 Apr;109:104744
Bioorganic chemistry 2021 Apr;109:104744
Heat shock protein 60 regulates yolk sac erythropoiesis in mice.
Duan Y, Wang H, Mitchell-Silbaugh K, Cai S, Fan F, Li Y, Tang H, Wang G, Fang X, Liu J, Jia N, Jing R, Ouyang K
Cell death & disease 2019 Oct 10;10(10):766
Cell death & disease 2019 Oct 10;10(10):766
Quantitative proteomics analysis of the role of tetraspanin-8 in the drug resistance of gastric cancer.
Li L, Yang D, Cui D, Li Y, Nie Z, Wang J, Liang L
International journal of oncology 2018 Feb;52(2):473-484
International journal of oncology 2018 Feb;52(2):473-484
Proteomics-based identification of VDAC1 as a tumor promoter in cervical carcinoma.
Zhang C, Ding W, Liu Y, Hu Z, Zhu D, Wang X, Yu L, Wang L, Shen H, Zhang W, Ren C, Li K, Weng D, Deng W, Ma D, Wang H
Oncotarget 2016 Aug 9;7(32):52317-52328
Oncotarget 2016 Aug 9;7(32):52317-52328
Mechanistic Study of the Phytocompound, 2- β -D-Glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-tetrayne in Human T-Cell Acute Lymphocytic Leukemia Cells by Using Combined Differential Proteomics and Bioinformatics Approaches.
Shiau JY, Yin SY, Chang SL, Hsu YJ, Chen KW, Kuo TF, Feng CS, Yang NS, Shyur LF, Yang WC, Wen TN
Evidence-based complementary and alternative medicine : eCAM 2015;2015:475610
Evidence-based complementary and alternative medicine : eCAM 2015;2015:475610
MYBL2 guides autophagy suppressor VDAC2 in the developing ovary to inhibit autophagy through a complex of VDAC2-BECN1-BCL2L1 in mammals.
Yuan J, Zhang Y, Sheng Y, Fu X, Cheng H, Zhou R
Autophagy 2015;11(7):1081-98
Autophagy 2015;11(7):1081-98
VDAC3 gating is activated by suppression of disulfide-bond formation between the N-terminal region and the bottom of the pore.
Okazaki M, Kurabayashi K, Asanuma M, Saito Y, Dodo K, Sodeoka M
Biochimica et biophysica acta 2015 Dec;1848(12):3188-96
Biochimica et biophysica acta 2015 Dec;1848(12):3188-96
Tumor Necrosis Factor-Associated Protein 1 (TRAP1) is Released from the Mitochondria Following 6-hydroxydopamine Treatment.
Shin DI, Oh YJ
Experimental neurobiology 2014 Mar;23(1):65-76
Experimental neurobiology 2014 Mar;23(1):65-76
Identification of sperm head proteins involved in zona pellucida binding.
Petit FM, Serres C, Bourgeon F, Pineau C, Auer J
Human reproduction (Oxford, England) 2013 Apr;28(4):852-65
Human reproduction (Oxford, England) 2013 Apr;28(4):852-65
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human heart tissue were subjected to SDS PAGE followed by western blot with 11663-1-AP(VDAC2 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The VDAC2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human VDAC2. This antibody recognizes human, mouse, rat antigen. The VDAC2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
