17476-1-AP
antibody from Proteintech Group
Targeting: CCR5
CC-CKR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22
Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 17476-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17476-1-AP, RRID:AB_10895966
- Product name
- CCR5 antibody
- Antibody type
- Polyclonal
- Description
- CCR5 antibody (Cat. #17476-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IHC,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Magnify is a universal molecular anchoring strategy for expansion microscopy.
Chordoma recruits and polarizes tumor-associated macrophages via secreting CCL5 to promote malignant progression.
Cancer associated fibroblast-derived CCL5 promotes hepatocellular carcinoma metastasis through activating HIF1α/ZEB1 axis.
PET-CT and RNA sequencing reveal novel targets for acupuncture-induced lowering of blood pressure in spontaneously hypertensive rats.
Targeting regulator of G protein signaling 1 in tumor-specific T cells enhances their trafficking to breast cancer.
CCR5 editing by Staphylococcus aureus Cas9 in human primary CD4(+) T cells and hematopoietic stem/progenitor cells promotes HIV-1 resistance and CD4(+) T cell enrichment in humanized mice.
Lack of susceptibility in neonatally infected rhesus macaques to simian immunodeficiency virus-induced encephalitis.
Regulation of C-C chemokine receptor 5 (CCR5) stability by Lys(197) and by transmembrane protein aptamers that target it for lysosomal degradation.
Beneficial properties of maraviroc on neuropathic pain development and opioid effectiveness in rats.
Klimas A, Gallagher BR, Wijesekara P, Fekir S, DiBernardo EF, Cheng Z, Stolz DB, Cambi F, Watkins SC, Brody SL, Horani A, Barth AL, Moore CI, Ren X, Zhao Y
Nature biotechnology 2023 Jun;41(6):858-869
Nature biotechnology 2023 Jun;41(6):858-869
Chordoma recruits and polarizes tumor-associated macrophages via secreting CCL5 to promote malignant progression.
Xu J, Shi Q, Lou J, Wang B, Wang W, Niu J, Guo L, Chen C, Yu Y, Huang Y, Guo W, Lan J, Zhu Y, Ren T, Tang X
Journal for immunotherapy of cancer 2023 Apr;11(4)
Journal for immunotherapy of cancer 2023 Apr;11(4)
Cancer associated fibroblast-derived CCL5 promotes hepatocellular carcinoma metastasis through activating HIF1α/ZEB1 axis.
Xu H, Zhao J, Li J, Zhu Z, Cui Z, Liu R, Lu R, Yao Z, Xu Q
Cell death & disease 2022 May 20;13(5):478
Cell death & disease 2022 May 20;13(5):478
PET-CT and RNA sequencing reveal novel targets for acupuncture-induced lowering of blood pressure in spontaneously hypertensive rats.
Li J, Peng C, Lai D, Fang Y, Luo D, Zhou Z, Li C, Lai X
Scientific reports 2021 May 26;11(1):10973
Scientific reports 2021 May 26;11(1):10973
Targeting regulator of G protein signaling 1 in tumor-specific T cells enhances their trafficking to breast cancer.
Huang D, Chen X, Zeng X, Lao L, Li J, Xing Y, Lu Y, Ouyang Q, Chen J, Yang L, Su F, Yao H, Liu Q, Su S, Song E
Nature immunology 2021 Jul;22(7):865-879
Nature immunology 2021 Jul;22(7):865-879
CCR5 editing by Staphylococcus aureus Cas9 in human primary CD4(+) T cells and hematopoietic stem/progenitor cells promotes HIV-1 resistance and CD4(+) T cell enrichment in humanized mice.
Xiao Q, Chen S, Wang Q, Liu Z, Liu S, Deng H, Hou W, Wu D, Xiong Y, Li J, Guo D
Retrovirology 2019 Jun 11;16(1):15
Retrovirology 2019 Jun 11;16(1):15
Lack of susceptibility in neonatally infected rhesus macaques to simian immunodeficiency virus-induced encephalitis.
Delery E, Bohannon DG, Irons DL, Allers C, Sugimoto C, Cai Y, Merino KM, Amedee AM, Veazey RS, MacLean A, Kuroda MJ, Kim WK
Journal of neurovirology 2019 Aug;25(4):578-588
Journal of neurovirology 2019 Aug;25(4):578-588
Regulation of C-C chemokine receptor 5 (CCR5) stability by Lys(197) and by transmembrane protein aptamers that target it for lysosomal degradation.
Petti LM, Marlatt SA, Luo Y, Scheideman EH, Shelar A, DiMaio D
The Journal of biological chemistry 2018 Jun 8;293(23):8787-8801
The Journal of biological chemistry 2018 Jun 8;293(23):8787-8801
Beneficial properties of maraviroc on neuropathic pain development and opioid effectiveness in rats.
Kwiatkowski K, Piotrowska A, Rojewska E, Makuch W, Jurga A, Slusarczyk J, Trojan E, Basta-Kaim A, Mika J
Progress in neuro-psychopharmacology & biological psychiatry 2016 Jan 4;64:68-78
Progress in neuro-psychopharmacology & biological psychiatry 2016 Jan 4;64:68-78
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CCR5 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human CCR5. This antibody recognizes human, mouse, rat antigen. The CCR5 antibody has been validated for the following applications: ELISA, WB analysis.