Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 15631-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15631-1-AP, RRID:AB_2120238
- Product name
- HSDL2 antibody
- Antibody type
- Polyclonal
- Description
- HSDL2 antibody (Cat. #15631-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Semaglutide Reduces Cardiomyocyte Damage Caused by High-Fat Through HSDL2.
Mitochondria-related HSDL2 is a potential biomarker in temporal lobe epilepsy by modulating astrocytic lipid metabolism.
HSDL2 links nutritional cues to bile acid and cholesterol homeostasis.
[HSDL2 overexpression promotes rectal cancer progression by regulating cancer cell cycle and promoting cell proliferation].
Cucurbitacin E inhibits cellular proliferation and induces apoptosis in melanoma by suppressing HSDL2 expression.
MiR-26a-5p regulates proliferation, apoptosis, migration and invasion via inhibiting hydroxysteroid dehydrogenase like-2 in cervical cancer cell.
HSDL2 Acts as a Promoter in Pancreatic Cancer by Regulating Cell Proliferation and Lipid Metabolism.
Ectopic expression of HSDL2 is related to cell proliferation and prognosis in breast cancer.
Proteome analysis of porcine epidemic diarrhea virus (PEDV)-infected Vero cells.
Yang L, Pan X, Pan Z, Gao H, Ban J, Chen S
Drug design, development and therapy 2024;18:5501-5515
Drug design, development and therapy 2024;18:5501-5515
Mitochondria-related HSDL2 is a potential biomarker in temporal lobe epilepsy by modulating astrocytic lipid metabolism.
Yang X, Zhang J, Wang Z, Yao Z, Yang X, Wang X, Zhao X, Xu S
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2024 Oct;21(6):e00447
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2024 Oct;21(6):e00447
HSDL2 links nutritional cues to bile acid and cholesterol homeostasis.
Samson N, Bosoi CR, Roy C, Turcotte L, Tribouillard L, Mouchiroud M, Berthiaume L, Trottier J, Silva HCG, Guerbette T, Plata-Gómez AB, Besse-Patin A, Montoni A, Ilacqua N, Lamothe J, Citron YR, Gélinas Y, Gobeil S, Zoncu R, Caron A, Morissette M, Pellegrini L, Rochette PJ, Estall JL, Efeyan A, Shum M, Audet-Walsh É, Barbier O, Marette A, Laplante M
Science advances 2024 May 31;10(22):eadk9681
Science advances 2024 May 31;10(22):eadk9681
[HSDL2 overexpression promotes rectal cancer progression by regulating cancer cell cycle and promoting cell proliferation].
Cheng Y, He X, Wang L, Xu Y, Shen M, Zhang W, Xia Y, Zhang J, Zhang M, Wang Y, Hu J, Hu J
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Apr 20;43(4):544-551
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Apr 20;43(4):544-551
Cucurbitacin E inhibits cellular proliferation and induces apoptosis in melanoma by suppressing HSDL2 expression.
Liu WB, Wang HL, Chen L, Tang B, Ke G, Wang S, Sun YQ, Ma J, Lyu DL
Chinese medicine 2022 Feb 22;17(1):28
Chinese medicine 2022 Feb 22;17(1):28
MiR-26a-5p regulates proliferation, apoptosis, migration and invasion via inhibiting hydroxysteroid dehydrogenase like-2 in cervical cancer cell.
Li M, Xiao Y, Liu M, Ning Q, Xiang Z, Zheng X, Tang S, Mo Z
BMC cancer 2022 Aug 10;22(1):876
BMC cancer 2022 Aug 10;22(1):876
HSDL2 Acts as a Promoter in Pancreatic Cancer by Regulating Cell Proliferation and Lipid Metabolism.
Han A, Xu R, Liu Y, Yin X, Lin Z, Yang W
OncoTargets and therapy 2021;14:435-444
OncoTargets and therapy 2021;14:435-444
Ectopic expression of HSDL2 is related to cell proliferation and prognosis in breast cancer.
Dong B, Yang Y, Han A, Zhang S, Lin Z, Wang Y, Piao J
Cancer management and research 2019;11:6531-6542
Cancer management and research 2019;11:6531-6542
Proteome analysis of porcine epidemic diarrhea virus (PEDV)-infected Vero cells.
Zeng S, Zhang H, Ding Z, Luo R, An K, Liu L, Bi J, Chen H, Xiao S, Fang L
Proteomics 2015 Jun;15(11):1819-28
Proteomics 2015 Jun;15(11):1819-28
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 15631-1-AP(HSDL2 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human prostate cancer using 15631-1-AP(HSDL2 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The HSDL2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HSDL2. This antibody recognizes human, mouse, rat antigen. The HSDL2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.