BS8721

antibody from Bioworld Technology, Inc
Targeting: ARFGAP1 ARF1GAP, bA261N11.3, FLJ10767
Provider product page for BS8721
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8721 - Provider product page
Provider
Bioworld Technology, Inc
Product name
ARFGAP1 polyclonal antibody
Antibody type
Polyclonal
Antigen
ADP-ribosylation factor GTPase-activating protein 1,ARF GAP 1 ,ADP-ribosylation factor 1 GTPase-activating protein,ARF1 GAP,ARF1-directed GTPase-activating protein,ARFGAP1,ARF1GAP
Description
ARFGAP1 (ADP-ribosylation factor GTPase activating protein 1), also known as ARF1 GAP, is a 406 amino acid protein that contains one ARF-GAP domain and localizes to the cytoplasm and the golgi apparatus. Functioning as a GTPase-activating protein (GAP), ARFGAP1 interacts with ARF1 and promotes hydrolysis of ARF1-bound GTP, an event that is required for both the dissociation of coat proteins from golgi structures and for the subsequent fusion of golgi vesicles with target compartments. When overexpressed, ARFGAP1, whose activity is inhibited by phosphatidylcholine and stimulated by phosphoinosides, can induce the redistribution of the entire golgi apparatus to the endoplasmic reticulum. Multiple isoforms of ARFGAP1 exist due to alternative splicing events.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ARFGAP1 protein structure - BS8721 shown in red.