SLC12A4

This gene encodes a member of the SLC12A transporter family. The encoded protein mediates the coupled movement of potassium and chloride ions across the plasma membrane. This gene is expressed ubiquitously. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jan 2013]

Description

Solute carrier family 12 member 4

Tissue specificity

Low tissue specificity

Subcell location

Endosomes

Predicted location

Membrane

Protein family

FDA approved drug targets
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
Transporters

Chromosome

16:q22.1 (67943474 - 67969601)

Ensembl ID

ENSG00000124067  (ver. 103.38)

Orthologs

Mouse Slc12a4: ENSMUSG00000017765

UniProt

Q9UP95

neXtProt

NX_Q9UP95

Human splice variants
Mouse splice variants