Antibody data
- Antibody Data
- Antigen structure
- References [21]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 24489-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- E2F7 antibody
- Antibody type
- Polyclonal
- Description
- E2F7 antibody (Cat. #24489-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Transducin-like enhancer of split 3 protects against lipopolysaccharide-induced inflammation through DEAD-box helicase 5-activating transcription factor 1-protein phosphatase 2 regulatory subunit 5A signaling.
Competitive Sequestration of miR-1183 by lncRNA DDX11-AS1 Drives Gliomagenesis through E2F7 Activation.
Single-cell MultiOmics and spatial transcriptomics demonstrate neuroblastoma developmental plasticity.
E2F7 transcriptionally upregulates SPC24 to mediate aerobic Glycolysis and facilitate stemness of breast cancer.
PRMT1 Upregulates SIRT6 by Enhancing Arginine Methylation of E2F7 to Inhibit Vascular Smooth Muscle Cell Senescence in Aortic Dissection.
E2F1 and E2F7 regulate gastric cancer cell proliferation, respectively, through transcriptional activation and transcriptional repression of MYBL2.
A Noninvasive Nanoeyedrop Therapy for the Inhibition of Uveal Melanoma: Tetrahedral Framework Nucleic Acid-Based Bioswitchable MicroRNA Delivery System.
A miRNA-based gene therapy nanodrug synergistically enhances pro-inflammatory antitumor immunity against melanoma.
Dexmedetomidine promotes ferroptotic cell death in gastric cancer via hsa_circ_0008035/miR-302a/E2F7 axis.
HOTAIRM1 Maintained the Malignant Phenotype of tMSCs Transformed by GSCs via E2F7 by Binding to FUS.
Comprehensive Analysis of the E2F Transcription Factor Family in Human Lung Adenocarcinoma.
Comprehensive analysis to identify the RP11-478C19.2/ E2F7 axis as a novel biomarker for treatment decisions in clear cell renal cell carcinoma.
APEX2-Mediated Proximity Labeling Resolves the DDIT4-Interacting Proteome.
Long noncoding RNA LINC00284 facilitates cell proliferation in papillary thyroid cancer via impairing miR-3127-5p targeted E2F7 suppression.
LINC00174 Facilitates Proliferation and Migration of Colorectal Cancer Cells via MiR-3127-5p/ E2F7 Axis.
E2F1/2/7/8 as independent indicators of survival in patients with cervical squamous cell carcinoma.
Do You Know the Details of Your PAX8 Antibody? Monoclonal PAX8 (MRQ-50) Is Not Expressed in a Series of 45 Medullary Thyroid Carcinomas.
Integrated Bioinformatics Analysis of Master Regulators in Anaplastic Thyroid Carcinoma.
Functional interplay between E2F7 and ribosomal rRNA gene transcription regulates protein synthesis.
HOXD-AS1/miR-130a sponge regulates glioma development by targeting E2F8.
The synthetic antihyperlipidemic drug potassium piperate selectively kills breast cancer cells through inhibiting G1-S-phase transition and inducing apoptosis.
Fan D, Zhong Y, Dong Y, Du M, Huang K, Li X
Journal of advanced research 2026 Jan;79:661-677
Journal of advanced research 2026 Jan;79:661-677
Competitive Sequestration of miR-1183 by lncRNA DDX11-AS1 Drives Gliomagenesis through E2F7 Activation.
Wang J, Yang X, Lin L, Yu J, Mao J
Oncology research 2025;33(10):3023-3040
Oncology research 2025;33(10):3023-3040
Single-cell MultiOmics and spatial transcriptomics demonstrate neuroblastoma developmental plasticity.
Xu Y, Lou D, Chen P, Li G, Usoskin D, Pan J, Li F, Huang S, Hess C, Tang R, Hu X, Yu J, Arceo M, de Krijger RR, Tischler AS, Schlisio S, Ernfors P, Hu Y, Wang J
Developmental cell 2025 Sep 8;60(17):2248-2263.e11
Developmental cell 2025 Sep 8;60(17):2248-2263.e11
E2F7 transcriptionally upregulates SPC24 to mediate aerobic Glycolysis and facilitate stemness of breast cancer.
Yun W, Mao C, Yuan Y
Journal of bioenergetics and biomembranes 2025 Oct;57(4-5):303-313
Journal of bioenergetics and biomembranes 2025 Oct;57(4-5):303-313
PRMT1 Upregulates SIRT6 by Enhancing Arginine Methylation of E2F7 to Inhibit Vascular Smooth Muscle Cell Senescence in Aortic Dissection.
Wu Y, Qin X, Xiang M, Deng J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 15;39(9):e70579
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 15;39(9):e70579
E2F1 and E2F7 regulate gastric cancer cell proliferation, respectively, through transcriptional activation and transcriptional repression of MYBL2.
Wu T, Jiang F, Wu F, Zheng G, Li Y, Wu L
The Journal of biological chemistry 2025 Jan;301(1):108027
The Journal of biological chemistry 2025 Jan;301(1):108027
A Noninvasive Nanoeyedrop Therapy for the Inhibition of Uveal Melanoma: Tetrahedral Framework Nucleic Acid-Based Bioswitchable MicroRNA Delivery System.
Jiang Z, Yang Y, Yue Z, Chen Y, Bai L, Wang R, Li S, Lin Y
ACS nano 2025 Apr 22;19(15):14756-14769
ACS nano 2025 Apr 22;19(15):14756-14769
A miRNA-based gene therapy nanodrug synergistically enhances pro-inflammatory antitumor immunity against melanoma.
Ma Y, Lin H, Wang P, Yang H, Yu J, Tian H, Li T, Ge S, Wang Y, Jia R, Leong KW, Ruan J
Acta biomaterialia 2023 Jan 1;155:538-553
Acta biomaterialia 2023 Jan 1;155:538-553
Dexmedetomidine promotes ferroptotic cell death in gastric cancer via hsa_circ_0008035/miR-302a/E2F7 axis.
Gao X, Wang XL
The Kaohsiung journal of medical sciences 2023 Apr;39(4):390-403
The Kaohsiung journal of medical sciences 2023 Apr;39(4):390-403
HOTAIRM1 Maintained the Malignant Phenotype of tMSCs Transformed by GSCs via E2F7 by Binding to FUS.
Liu L, Zhou Y, Dong X, Li S, Cheng S, Li H, Li Y, Yuan J, Wang L, Dong J
Journal of oncology 2022;2022:7734413
Journal of oncology 2022;2022:7734413
Comprehensive Analysis of the E2F Transcription Factor Family in Human Lung Adenocarcinoma.
Wang Q, Liu J, Cheang I, Li J, Chen T, Li Y, Yu B
International journal of general medicine 2022;15:5973-5984
International journal of general medicine 2022;15:5973-5984
Comprehensive analysis to identify the RP11-478C19.2/ E2F7 axis as a novel biomarker for treatment decisions in clear cell renal cell carcinoma.
Zeng K, Song G, Chen B, Gao X, Liu C, Miao J, Ruan Y, Luan Y, Chen X, Liu J, Li Q, Liu B
Translational oncology 2022 Nov;25:101525
Translational oncology 2022 Nov;25:101525
APEX2-Mediated Proximity Labeling Resolves the DDIT4-Interacting Proteome.
Naki M, Gourdomichali O, Zonke K, Kattan FG, Makridakis M, Kontostathi G, Vlahou A, Doxakis E
International journal of molecular sciences 2022 May 6;23(9)
International journal of molecular sciences 2022 May 6;23(9)
Long noncoding RNA LINC00284 facilitates cell proliferation in papillary thyroid cancer via impairing miR-3127-5p targeted E2F7 suppression.
Zhou B, Ge Y, Shao Q, Yang L, Chen X, Jiang G
Cell death discovery 2021 Jun 26;7(1):156
Cell death discovery 2021 Jun 26;7(1):156
LINC00174 Facilitates Proliferation and Migration of Colorectal Cancer Cells via MiR-3127-5p/ E2F7 Axis.
Ma Y, Li Y, Tang Y, Tang N, Wang D, Li X
Journal of microbiology and biotechnology 2021 Aug 28;31(8):1098-1108
Journal of microbiology and biotechnology 2021 Aug 28;31(8):1098-1108
E2F1/2/7/8 as independent indicators of survival in patients with cervical squamous cell carcinoma.
Yang C, Zhang ZC, Liu TB, Xu Y, Xia BR, Lou G
Cancer cell international 2020;20:500
Cancer cell international 2020;20:500
Do You Know the Details of Your PAX8 Antibody? Monoclonal PAX8 (MRQ-50) Is Not Expressed in a Series of 45 Medullary Thyroid Carcinomas.
Gucer H, Caliskan S, Kefeli M, Mete O
Endocrine pathology 2020 Mar;31(1):33-38
Endocrine pathology 2020 Mar;31(1):33-38
Integrated Bioinformatics Analysis of Master Regulators in Anaplastic Thyroid Carcinoma.
Pan Z, Li L, Fang Q, Qian Y, Zhang Y, Zhu J, Ge M, Huang P
BioMed research international 2019;2019:9734576
BioMed research international 2019;2019:9734576
Functional interplay between E2F7 and ribosomal rRNA gene transcription regulates protein synthesis.
Coutts AS, Munro S, La Thangue NB
Cell death & disease 2018 May 1;9(5):577
Cell death & disease 2018 May 1;9(5):577
HOXD-AS1/miR-130a sponge regulates glioma development by targeting E2F8.
Chen Y, Zhao F, Cui D, Jiang R, Chen J, Huang Q, Shi J
International journal of cancer 2018 Jun 1;142(11):2313-2322
International journal of cancer 2018 Jun 1;142(11):2313-2322
The synthetic antihyperlipidemic drug potassium piperate selectively kills breast cancer cells through inhibiting G1-S-phase transition and inducing apoptosis.
Fan L, Cao X, Yan H, Wang Q, Tian X, Zhang L, He X, Borjihan G, Morigen
Oncotarget 2017 Jul 18;8(29):47250-47268
Oncotarget 2017 Jul 18;8(29):47250-47268
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 24489-1-AP( E2F7 Antibody) at dilution of 1:600
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The E2F7 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human E2F7. This antibody recognizes human antigen. The E2F7 antibody has been validated for the following applications: ELISA, WB, IHC analysis.