BS8333

antibody from Bioworld Technology, Inc
Targeting: MTA3 KIAA1266
Provider product page for BS8333
Western blot
Immunohistochemistry

Antibody data

Product number
BS8333 - Provider product page
Provider
Bioworld Technology, Inc
Product name
MTA3 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human MTA3.
Description
Metastasis-associated protein 3 (MTA3) is a subunit of the Mi-2/NuRD transcriptional corepressor complex. MTA3 and the Mi-2/NuRD complex mediate repression of Snail in breast cancer cells where MTA3 works to maintain a differentiated, epithelial status. The protein is involved in gene expression regulation by covalent modifications of histone proteins. There are two known isoforms of MTA3, a short and a long form. The short isoform binds to ER and sequesters it to the cytoplasm and betters non-genomic responses, whereas the long form is found in the nucleus. MTA3 is widely expressed in with highest expression in brain, adrenal glands, ovaries and virgin mammary glands. It has been found to be expressed in higher levels in tumors than in adjacent normal tissue in the same individual.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
MTA3 protein structure - BS8333 shown in red.