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- Antibody Data
- Antigen structure
- References [17]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 22117-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#22117-1-AP, RRID:AB_11183753
- Product name
- MYPT1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated MYPT1 antibody (Cat. #22117-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Apurinic/apyrimidinic endodeoxyribonuclease 1 (APE1) promotes stress granule formation via YBX1 phosphorylation in ovarian cancer.
Role of ZIP kinase in development of myofibroblast differentiation from HPMCs.
Differential expression of PPP1R12A transcripts, including those harbouring alternatively spliced micro-exons, in placentae from complicated pregnancies.
FDCA Attenuates Neuroinflammation and Brain Injury after Cerebral Ischemic Stroke.
Morphological and Functional Colonic Defects Caused by a Mutated Thyroid Hormone Receptor α.
Pinocembrin attenuates susceptibility to atrial fibrillation in rats with pulmonary arterial hypertension.
MYPT1 inhibits the metastasis of renal clear cell carcinoma via the MAPK8/N-cadherin pathway.
MYPT1 reduction is a pathogenic factor of erectile dysfunction.
Chlorogenic acid improves the intestinal barrier by relieving endoplasmic reticulum stress and inhibiting ROCK/MLCK signaling pathways.
MicroRNA-455-5p Contributes to Cholangiocarcinoma Growth and Mediates Galangin's Anti-Tumor Effects.
Mitotic Acetylation of Microtubules Promotes Centrosomal PLK1 Recruitment and Is Required to Maintain Bipolar Spindle Homeostasis.
Smad4 regulates the nuclear translocation of Nkx2-5 in cardiac differentiation.
RhoA/ROCK Pathway Activation is Regulated by AT1 Receptor and Participates in Smooth Muscle Migration and Dedifferentiation via Promoting Actin Cytoskeleton Polymerization.
Effects of Dexmedetomidine on the RhoA /ROCK/ Nox4 Signaling Pathway in Renal Fibrosis of Diabetic Rats.
Nicotine facilitates VSMC dysfunction through a miR-200b/RhoGDIA/cytoskeleton module.
Madagascine Induces Vasodilatation via Activation of AMPK.
MicroRNA-223 Attenuates Hypoxia-induced Vascular Remodeling by Targeting RhoB/MLC2 in Pulmonary Arterial Smooth Muscle Cells.
Mao S, Xie C, Liu Y, Zhao Y, Li M, Gao H, Xiao Y, Zou Y, Zheng Z, Gao Y, Xie J, Tian B, Wang L, Hua Y, Xu H
Cellular and molecular life sciences : CMLS 2024 Mar 4;81(1):113
Cellular and molecular life sciences : CMLS 2024 Mar 4;81(1):113
Role of ZIP kinase in development of myofibroblast differentiation from HPMCs.
Choo YY, Sakai T, Ikebe R, Jeffers A, Idell S, Tucker TA, Ikebe M
American journal of physiology. Lung cellular and molecular physiology 2024 Mar 1;326(3):L353-L366
American journal of physiology. Lung cellular and molecular physiology 2024 Mar 1;326(3):L353-L366
Differential expression of PPP1R12A transcripts, including those harbouring alternatively spliced micro-exons, in placentae from complicated pregnancies.
Frew E, Sainty R, Chappell-Maor L, Bone C, Daskeviciute D, Russell S, Buhigas C, Iglesias-Platas I, Lartey J, Monk D
Placenta 2024 Jun;151:1-9
Placenta 2024 Jun;151:1-9
FDCA Attenuates Neuroinflammation and Brain Injury after Cerebral Ischemic Stroke.
Guan X, Wei D, Liang Z, Xie L, Wang Y, Huang Z, Wu J, Pang T
ACS chemical neuroscience 2023 Oct 18;14(20):3839-3854
ACS chemical neuroscience 2023 Oct 18;14(20):3839-3854
Morphological and Functional Colonic Defects Caused by a Mutated Thyroid Hormone Receptor α.
Kim M, Kruhlak M, Hoffmann V, Zerfas P, Bishop K, Doolittle WKL, Edmondson EF, Zhu YJ, Cheng SY
Thyroid : official journal of the American Thyroid Association 2023 Feb;33(2):239-250
Thyroid : official journal of the American Thyroid Association 2023 Feb;33(2):239-250
Pinocembrin attenuates susceptibility to atrial fibrillation in rats with pulmonary arterial hypertension.
Yi Y, Tianxin Y, Zhangchi L, Cui Z, Weiguo W, Bo Y
European journal of pharmacology 2023 Dec 5;960:176169
European journal of pharmacology 2023 Dec 5;960:176169
MYPT1 inhibits the metastasis of renal clear cell carcinoma via the MAPK8/N-cadherin pathway.
Xie Q, Liu R, Zou Z, Feng Y, Huang Y, Xu G, Sun W, Liang Y, Zhong W
FEBS open bio 2022 Nov;12(11):2083-2095
FEBS open bio 2022 Nov;12(11):2083-2095
MYPT1 reduction is a pathogenic factor of erectile dysfunction.
Zhao W, Sun J, Yao LY, Hang D, Li YQ, Chen CP, Zhou YW, Chen X, Tao T, Wei LS, Zheng YY, Ge X, Li CJ, Xin ZC, Pan Y, Wang XZ, He WQ, Zhang XN, Yao B, Zhu MS
Communications biology 2022 Jul 25;5(1):744
Communications biology 2022 Jul 25;5(1):744
Chlorogenic acid improves the intestinal barrier by relieving endoplasmic reticulum stress and inhibiting ROCK/MLCK signaling pathways.
Song L, Wu T, Zhang L, Wan J, Ruan Z
Food & function 2022 Apr 20;13(8):4562-4575
Food & function 2022 Apr 20;13(8):4562-4575
MicroRNA-455-5p Contributes to Cholangiocarcinoma Growth and Mediates Galangin's Anti-Tumor Effects.
Deng X, Zuo M, Pei Z, Xie Y, Yang Z, Zhang Z, Jiang M, Kuang D
Journal of Cancer 2021;12(15):4710-4721
Journal of Cancer 2021;12(15):4710-4721
Mitotic Acetylation of Microtubules Promotes Centrosomal PLK1 Recruitment and Is Required to Maintain Bipolar Spindle Homeostasis.
Rasamizafy SF, Delsert C, Rabeharivelo G, Cau J, Morin N, van Dijk J
Cells 2021 Jul 22;10(8)
Cells 2021 Jul 22;10(8)
Smad4 regulates the nuclear translocation of Nkx2-5 in cardiac differentiation.
Hu W, Dong A, Karasaki K, Sogabe S, Okamoto D, Saigo M, Ishida M, Yoshizumi M, Kokubo H
Scientific reports 2021 Feb 11;11(1):3588
Scientific reports 2021 Feb 11;11(1):3588
RhoA/ROCK Pathway Activation is Regulated by AT1 Receptor and Participates in Smooth Muscle Migration and Dedifferentiation via Promoting Actin Cytoskeleton Polymerization.
Qi Y, Liang X, Dai F, Guan H, Sun J, Yao W
International journal of molecular sciences 2020 Jul 29;21(15)
International journal of molecular sciences 2020 Jul 29;21(15)
Effects of Dexmedetomidine on the RhoA /ROCK/ Nox4 Signaling Pathway in Renal Fibrosis of Diabetic Rats.
Jihua C, Cai C, Xubin B, Yue Y
Open medicine (Warsaw, Poland) 2019;14:890-898
Open medicine (Warsaw, Poland) 2019;14:890-898
Nicotine facilitates VSMC dysfunction through a miR-200b/RhoGDIA/cytoskeleton module.
Liang D, Wang Z, Yan Z, Hou S, Xu W, Wang L, Shang M, Qiao Z
Scientific reports 2017 Mar 2;7:43798
Scientific reports 2017 Mar 2;7:43798
Madagascine Induces Vasodilatation via Activation of AMPK.
Chen D, Lv B, Kobayashi S, Xiong Y, Sun P, Lin Y, Genovese S, Epifano F, Hou S, Tang F, Ji Y, Yu D
Frontiers in pharmacology 2016;7:435
Frontiers in pharmacology 2016;7:435
MicroRNA-223 Attenuates Hypoxia-induced Vascular Remodeling by Targeting RhoB/MLC2 in Pulmonary Arterial Smooth Muscle Cells.
Zeng Y, Zhang X, Kang K, Chen J, Wu Z, Huang J, Lu W, Chen Y, Zhang J, Wang Z, Zhai Y, Qu J, Ramchandran R, Raj JU, Wang J, Gou D
Scientific reports 2016 Apr 28;6:24900
Scientific reports 2016 Apr 28;6:24900
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 22117-1-AP(MYPT1 antibody) at dilution of 1:3000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human heart using 22117-1-AP(MYPT1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MYPT1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human MYPT1. This antibody recognizes human,mouse,rat antigen. The MYPT1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
