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- Antibody Data
- Antigen structure
- References [6]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 18697-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18697-1-AP, RRID:AB_2284691
- Product name
- BRK antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated BRK antibody (Cat. #18697-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Prognostic analysis and mechanistic exploration of the autophagy-related exosome genes ITGA3, ITGB4, and PTK6 in pancreatic ductal adenocarcinoma.
PTK6 drives HNRNPH1 phase separation to activate autophagy and suppress apoptosis in colorectal cancer.
ETV4 Mediated Tumor-Associated Neutrophil Infiltration Facilitates Lymphangiogenesis and Lymphatic Metastasis of Bladder Cancer.
Genome-Wide Identification of Autophagy Prognostic Signature in Pancreatic Cancer.
The expression and prognostic value of protein tyrosine kinase 6 in early-stage cervical squamous cell cancer.
RSK promotes prostate cancer progression in bone through ING3, CKAP2, and PTK6-mediated cell survival.
Liang L, Guo P, Xiao M, Zu F, Hao G, Zhang C, Liu Q
Discover oncology 2025 Jul 1;16(1):1204
Discover oncology 2025 Jul 1;16(1):1204
PTK6 drives HNRNPH1 phase separation to activate autophagy and suppress apoptosis in colorectal cancer.
Chen B, Liu B, Chen J, Li W, Ma N, Liu J, Fan R, Hu Q, Song H, Xu Y, Jiang T, Song J
Autophagy 2025 Aug;21(8):1680-1699
Autophagy 2025 Aug;21(8):1680-1699
ETV4 Mediated Tumor-Associated Neutrophil Infiltration Facilitates Lymphangiogenesis and Lymphatic Metastasis of Bladder Cancer.
Zhang Q, Liu S, Wang H, Xiao K, Lu J, Chen S, Huang M, Xie R, Lin T, Chen X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Apr;10(11):e2205613
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Apr;10(11):e2205613
Genome-Wide Identification of Autophagy Prognostic Signature in Pancreatic Cancer.
Yu J, Lang Q, Zhong C, Wang S, Tian Y
Dose-response : a publication of International Hormesis Society 2021 Apr-Jun;19(2):15593258211023260
Dose-response : a publication of International Hormesis Society 2021 Apr-Jun;19(2):15593258211023260
The expression and prognostic value of protein tyrosine kinase 6 in early-stage cervical squamous cell cancer.
Wang XJ, Xiong Y, Ma ZB, Xia JC, Li YF
Chinese journal of cancer 2016 Jun 16;35(1):54
Chinese journal of cancer 2016 Jun 16;35(1):54
RSK promotes prostate cancer progression in bone through ING3, CKAP2, and PTK6-mediated cell survival.
Yu G, Lee YC, Cheng CJ, Wu CF, Song JH, Gallick GE, Yu-Lee LY, Kuang J, Lin SH
Molecular cancer research : MCR 2015 Feb;13(2):348-57
Molecular cancer research : MCR 2015 Feb;13(2):348-57
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- MCF7 cells were subjected to SDS PAGE followed by western blot with 18697-1-AP(PTK6 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of MCF-7 cells, using PTK6 antibody 18697-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon using 18697-1-AP(PTK6 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon using 18697-1-AP(PTK6 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
