Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [2]
- Immunocytochemistry [1]
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Validation data
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- Product number
- H00005753-B01P - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00005753-B01P, RRID:AB_2300534
- Product name
- Mouse Polyclonal Brk Antibody
- Antibody type
- Polyclonal
- Description
- Protein A purified. PTK6 - PTK6 protein tyrosine kinase 6,
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.05 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Marine natural products-inspired phenylmethylene hydantoins with potent in vitro and in vivo antitumor activities via suppression of Brk and FAK signaling.
Optimization, pharmacophore modeling and 3D-QSAR studies of sipholanes as breast cancer migration and proliferation inhibitors.
The marine-derived sipholenol A-4-O-3',4'-dichlorobenzoate inhibits breast cancer growth and motility in vitro and in vivo through the suppression of Brk and FAK signaling.
Sallam AA, Mohyeldin MM, Foudah AI, Akl MR, Nazzal S, Meyer SA, Liu YY, El Sayed KA
Organic & biomolecular chemistry 2014 Jul 28;12(28):5295-303
Organic & biomolecular chemistry 2014 Jul 28;12(28):5295-303
Optimization, pharmacophore modeling and 3D-QSAR studies of sipholanes as breast cancer migration and proliferation inhibitors.
Foudah AI, Sallam AA, Akl MR, El Sayed KA
European journal of medicinal chemistry 2014 Feb 12;73:310-24
European journal of medicinal chemistry 2014 Feb 12;73:310-24
The marine-derived sipholenol A-4-O-3',4'-dichlorobenzoate inhibits breast cancer growth and motility in vitro and in vivo through the suppression of Brk and FAK signaling.
Akl MR, Foudah AI, Ebrahim HY, Meyer SA, El Sayed KA
Marine drugs 2014 Apr 14;12(4):2282-304
Marine drugs 2014 Apr 14;12(4):2282-304
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Brk Antibody [H00005753-B01P] - Analysis of PTK6 expression in transfected 293T cell line by PTK6 polyclonal antibody. Lane 1: PTK6 transfected lysate(49.61 KDa). Lane 2: Non-transfected lysate.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Brk Antibody [H00005753-B01P] - Analysis of PTK6 expression in human colon.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunocytochemistry/Immunofluorescence: Brk Antibody [H00005753-B01P] - Analysis of purified antibody to PTK6 on HeLa cell. (antibody concentration 10 ug/ml)