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- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
- Immunohistochemistry [5]
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- Product number
- NBP1-84045 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-84045, RRID:AB_11037283
- Product name
- Rabbit Polyclonal SEC62 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human SEC62 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human, Canine
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Intrinsically Disordered Protein TEX264 Mediates ER-phagy.
Mammalian SRP receptor switches the Sec61 translocase from Sec62 to SRP-dependent translocation.
Systematic interrogation of 3q26 identifies TLOC1 and SKIL as cancer drivers.
Chino H, Hatta T, Natsume T, Mizushima N
Molecular cell 2019 Jun 6;74(5):909-921.e6
Molecular cell 2019 Jun 6;74(5):909-921.e6
Mammalian SRP receptor switches the Sec61 translocase from Sec62 to SRP-dependent translocation.
Jadhav B, McKenna M, Johnson N, High S, Sinning I, Pool MR
Nature communications 2015 Dec 4;6:10133
Nature communications 2015 Dec 4;6:10133
Systematic interrogation of 3q26 identifies TLOC1 and SKIL as cancer drivers.
Hagerstrand D, Tong A, Schumacher SE, Ilic N, Shen RR, Cheung HW, Vazquez F, Shrestha Y, Kim SY, Giacomelli AO, Rosenbluh J, Schinzel AC, Spardy NA, Barbie DA, Mermel CH, Weir BA, Garraway LA, Tamayo P, Mesirov JP, Beroukhim R, Hahn WC
Cancer discovery 2013 Sep;3(9):1044-57
Cancer discovery 2013 Sep;3(9):1044-57
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: SEC62 Antibody [NBP1-84045] - Analysis in human cell line A-431.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: SEC62 Antibody [NBP1-84045] - Staining of human prostate shows moderate cytoplasmic positivity in glandular cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: SEC62 Antibody [NBP1-84045] - Staining of human cerebral cortex shows strong cytoplasmic positivity in neurons.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: SEC62 Antibody [NBP1-84045] - Staining of human skeletal muscle shows weak cytoplasmic positivity in myocytes.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: SEC62 Antibody [NBP1-84045] - Staining of human endometrium shows moderate cytoplasmic positivity in glandular cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: SEC62 Antibody [NBP1-84045] - Staining of human prostate shows moderate cytoplasmic positivity in glandular cells.
